A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA

An efficient recombination system for chromosome engineering in Escherichia coli

2000 • 1,679 citations

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

1992 • 1,651 citations

A new logic for DNA engineering using recombination in Escherichia coli

1998 • 1,199 citations

Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization

1997 • 858 citations

Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue

1997 • 664 citations

Rapid modification of bacterial artificial chromosomes by ET- recombination

1999 • 533 citations

Targeted Mutagenesis of the Endogenous Mouse Mis Gene Promoter

1999 • 431 citations

Neuron Specific Enolase, A Clinically Useful Marker for Neurons and Neuroendocrine Cells

1987 • 414 citations

Improved properties of FLP recombinase evolved by cycling mutagenesis

1998 • 406 citations

Efficient and precise engineering of a 200 kb β-globin human/bacterial artificial chromosome in E. coli DH10B using an inducible homologous recombination system

1999 • 143 citations

Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.

1998 • 118 citations

Cosmid DNA packaging in vivo

1982 • 54 citations