Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1999 • 8,261 citations

Ghrelin induces adiposity in rodents

2000 • 3,915 citations

A role for ghrelin in the central regulation of feeding

2001 • 3,415 citations

A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans

2001 • 2,865 citations

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

1996 • 2,844 citations

Circulating Ghrelin Levels Are Decreased in Human Obesity

2001 • 1,999 citations

Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans¹

2000 • 1,794 citations

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

2003 • 1,617 citations

The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion

2000 • 1,521 citations

Ghrelin Causes Hyperphagia and Obesity in Rats

2001 • 1,121 citations

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1996 • 1,020 citations

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

1999 • 1,000 citations

Ghrelin Stimulates Gastric Acid Secretion and Motility in Rats

2000 • 875 citations

Deletion of Ghrelin Impairs neither Growth nor Appetite

2003 • 631 citations

Co-Localization of Growth Hormone Secretagogue Receptor and NPY mRNA in the Arcuate Nucleus of the Rat

1999 • 592 citations

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

2003 • 572 citations

The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis

2001 • 564 citations

Food Fails to Suppress Ghrelin Levels in Obese Humans

2002 • 517 citations

Neither Agouti-Related Protein nor Neuropeptide Y Is Critically Required for the Regulation of Energy Homeostasis in Mice

2002 • 421 citations

Ghrelin Acts in the Central Nervous System to Stimulate Gastric Acid Secretion

2001 • 384 citations

Ciliary Neurotrophic Factor and Stress Stimuli Activate the Jak-STAT Pathway in Retinal Neurons and Glia

2000 • 259 citations

Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus

2002 • 257 citations

Agouti-Related Peptide, Neuropeptide Y, and Somatostatin-Producing Neurons Are Targets for Ghrelin Actions in the Rat Hypothalamus

2003 • 229 citations

Delayed Short-Term Secretory Regulation of Ghrelin in Obese Animals: Evidenced by a Specific RIA for the Active Form of Ghrelin

2002 • 215 citations

RAPID COMMUNICATIONS: Mutations in the Preproghrelin/Ghrelin Gene Associated with Obesity in Humans

2001 • 213 citations

GH-Releasing Peptide-2 Increases Fat Mass in Mice Lacking NPY: Indication for a Crucial Mediating Role of Hypothalamic Agouti-Related Protein

2002 • 151 citations

Ghrelin, Macronutrient Intake and Dietary Preferences in Long–Evans Rats

2002 • 131 citations

Ghrelin Gene: Identification of Missense Variants and a Frameshift Mutation in Extremely Obese Children and Adolescents and Healthy Normal Weight Students

2002 • 123 citations

Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice

2003 • 95 citations

Deleted Work

1955 • 0 citations