Role of lysophosphatidylcholine in T-lymphocyte activation: involvement of phospholipase A2 in signal transduction through protein kinase C.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

Changes of free calcium levels with stages of the cell division cycle

1985 • 591 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications.

1991 • 316 citations

Regulation of protein kinase C by lysophospholipids. Potential role in signal transduction.

1988 • 270 citations

Protein kinase C and T cell activation

1990 • 183 citations

Phorbol ester and neomycin dissociate bradykinin receptor-mediated arachidonic acid release and polyphosphoinositide hydrolysis in Madin-Darby canine kidney cells. Evidence that bradykinin mediates noninterdependent activation of phospholipases A2 and C.

1988 • 167 citations

Activation of resting human T cells requires prolonged stimulation of protein kinase C.

1990 • 99 citations

Platelet activation by simultaneous actions of diacylglycerol and unsaturated fatty acids.

1992 • 65 citations

Metabolic rate of membrane-permeant diacylglycerol and its relation to human resting T-lymphocyte activation.

1991 • 58 citations

Lysophosphatidylcholine as a possible second messenger synergistic to diacylglycerol and calcium ion for T-lymphocyte activation

1991 • 50 citations

Lysophosphatidylcholine induces mast cell secretion and protein kinase C activation

1991 • 30 citations