Lysophosphatidylcholine as a possible second messenger synergistic to diacylglycerol and calcium ion for T-lymphocyte activation

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers

1988 • 512 citations

Protein kinase C and T cell activation

1990 • 183 citations

The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies.

1987 • 153 citations

Diacylglycerol kinase from pig brain. Purification and phospholipid dependencies.

1983 • 135 citations

Human T cell activation by phorbol esters and diacylglycerol analogues.

1989 • 84 citations

Activation signals in human lymphocytes. Incorporation of polyunsaturated fatty acids into plasma membrane phospholipids regulates IL-2 synthesis via sustained activation of protein kinase C.

1989 • 79 citations

Purification and characterization of membrane-bound and cytosolic forms of diacylglycerol kinase from rat brain.

1990 • 57 citations

Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol

1987 • 38 citations

Activation signals in human lymphocytes: Interleukin 2 synthesis and expression of high affinity interleukin 2 receptors require differential signalling for the activation of protein kinase C

1990 • 24 citations

Activation of human T cells with the physiological regulator of protein kinase C

1988 • 18 citations

Induction of Responsiveness to Interleukin 2 in Mouse Lymphocytes by Synergistic Action of Ionophore A 23187 and Diacylglycerol

1987 • 7 citations