Metabolic rate of membrane-permeant diacylglycerol and its relation to human resting T-lymphocyte activation.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

1983 • 705 citations

Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers

1988 • 512 citations

Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications.

1991 • 316 citations

Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.

1985 • 234 citations

The nature of protein kinase C activation by physically defined phospholipid vesicles and diacylglycerols.

1985 • 228 citations

Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.

1985 • 218 citations

Protein kinase C and T cell activation

1990 • 183 citations

The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies.

1987 • 153 citations

The stereospecific activation of protein kinase C

1984 • 135 citations

Failure of 1-oleoyl-2-acetylglycerol to mimic the cell-differentiating action of 12-O-tetradecanoylphorbol 13-acetate in HL-60 cells.

1985 • 125 citations

Activation of resting human T cells requires prolonged stimulation of protein kinase C.

1990 • 99 citations

Human T cell activation by phorbol esters and diacylglycerol analogues.

1989 • 84 citations

Isolation of protein kinase C subspecies from a preparation of human T lymphocytes

1988 • 60 citations

Multiple doses of diacylglycerol and calcium ionophore are necessary to activate AP-1 enhancer activity and induce markers of macrophage differentiation.

1990 • 60 citations

Disparate effects of activators of protein kinase C on HL-60 promyelocytic leukemia cell differentiation.

1987 • 60 citations

Stereospecificity of diacylglycerol for stimulus-response coupling in platelets

1986 • 58 citations

T cell activation induced by anti-CD3 antibodies requires prolonged stimulation of protein kinase C

1989 • 35 citations

Activation signals in human lymphocytes: Interleukin 2 synthesis and expression of high affinity interleukin 2 receptors require differential signalling for the activation of protein kinase C

1990 • 24 citations

Activation of human T cells with the physiological regulator of protein kinase C

1988 • 18 citations

Induction of Responsiveness to Interleukin 2 in Mouse Lymphocytes by Synergistic Action of Ionophore A 23187 and Diacylglycerol

1987 • 7 citations