Bystander Cells and Prognosis in Hodgkin Lymphoma

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments]

1994 • 6,495 citations

World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

2002 • 4,781 citations

Report of the Committee on Hodgkin's Disease Staging Classification.

1971 • 4,212 citations

World Health Organization Classification of Neoplastic Diseases of the Hematopoietic and Lymphoid Tissues: Report of the Clinical Advisory Committee Meeting—Airlie House, Virginia, November 1997

1999 • 3,357 citations

A Prognostic Score for Advanced Hodgkin's Disease

1998 • 1,694 citations

Mast cells

1997 • 1,636 citations

Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting.

1989 • 1,597 citations

Characterization of single-nucleotide polymorphisms in coding regions of human genes

1999 • 1,531 citations

Combination Chemotherapy in the Treatment of Advanced Hodgkin's Disease

1970 • 1,450 citations

Chemotherapy of Advanced Hodgkin's Disease with MOPP, ABVD, or MOPP Alternating with ABVD

1992 • 1,159 citations

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

1997 • 1,091 citations

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

1999 • 937 citations

Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells

1982 • 878 citations

[Hodgkin's disease].

1988 • 829 citations

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

1997 • 780 citations

Journal of the National Cancer Institute

1958 • 779 citations

The pathology and nomenclature of Hodgkin's disease.

1972 • 762 citations

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

1996 • 749 citations

Establishment of an immature mast cell line from a patient with mast cell leukemia

1988 • 749 citations

Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP

1975 • 749 citations

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.

1994 • 691 citations

Thyroid Diseases after Treatment of Hodgkin's Disease

1991 • 571 citations

Lung Cancer Following Chemotherapy and Radiotherapy for Hodgkin's Disease

2002 • 548 citations

Breast Cancer After Treatment of Hodgkin's Disease

1993 • 547 citations

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

1993 • 541 citations

The role of cytokines in classical Hodgkin lymphoma

2002 • 514 citations

Natural history of Hodgkin's disease as related to its pathologic picture

1966 • 513 citations

On Some Morbid Appearances of the Absorbent Glands and Spleen

1832 • 500 citations

Epidemiology of Hodgkin's Disease

1973 • 492 citations

Curability of Advanced Hodgkin's Disease with Chemotherapy

1980 • 466 citations

Twenty years of MOPP therapy for Hodgkin's disease.

1986 • 446 citations

A Transplantable Mast-Cell Neoplasm in the Mouse

1957 • 438 citations

Mechanism of membrane damage mediated by human eosinophil cationic protein

1986 • 415 citations

Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.

1989 • 411 citations

Mast cells in innate immunity

2000 • 403 citations

High Expression of the CC Chemokine TARC in Reed-Sternberg Cells

1999 • 379 citations

The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis.

1995 • 378 citations

Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells.

1997 • 347 citations

Concordance for Hodgkin's Disease in Identical Twins Suggesting Genetic Susceptibility to the Young-Adult Form of the Disease

1995 • 335 citations

High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells

1996 • 328 citations

Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells.

1996 • 324 citations

The World Health Organization Classification of Neoplasms of the Hematopoietic and Lymphoid Tissues: Report of the Clinical Advisory Committee Meeting – Airlie House, Virginia, November, 1997

2000 • 324 citations

Monoclonal antibodies distinguish between storage and secreted forms of eosinophil cationic protein

1984 • 319 citations

Stanford V and Radiotherapy for Locally Extensive and Advanced Hodgkin's Disease: Mature Results of a Prospective Clinical Trial

2002 • 309 citations

Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines

1994 • 303 citations

The Radical Radiotherapy of Regionally Localized Hodgkin's Disease

1962 • 303 citations

Antibacterial properties of eosinophil major basic protein and eosinophil cationic protein.

1989 • 295 citations

Epidemiologic patterns of Hodgkin's Disease

1971 • 293 citations

The management of stage I--II Hodgkin's disease with irradiation alone or combined modality therapy: the Stanford experience

1982 • 291 citations

Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription

2001 • 287 citations

Clonal Deleterious Mutations in the Iκbα Gene in the Malignant Cells in Hodgkin's Lymphoma

2000 • 287 citations

Neutrophil Recruitment by Tumor Necrosis Factor from Mast Cells in Immune Complex Peritonitis

1992 • 285 citations

Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease

1999 • 284 citations

Ventilation of Operating-theatres

1964 • 275 citations

A new leukemia cell line with philadelphia chromosome characterized as basophil precursors

1985 • 261 citations

Hodgkin's Disease and Allied Disorders

1939 • 260 citations

Phenotypic Characterization of the Human Mast‐Cell Line HMC‐1

1994 • 259 citations

Tumour-associated eosinophilia: a review.

1981 • 255 citations

The significance of mediastinal involvement in early stage Hodgkin's disease

1978 • 248 citations

Influence of more extensive radiotherapy and adjuvant chemotherapy on long-term outcome of early-stage Hodgkin's disease: a meta-analysis of 23 randomized trials involving 3,888 patients. International Hodgkin's Disease Collaborative Group.

1998 • 246 citations

Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor.

1987 • 245 citations

Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein.

1986 • 242 citations

High risk of breast carcinoma after irradiation of young women with Hodgkin's disease

1997 • 232 citations

Hodgkin's Disease: A clinicopathologic study of 659 cases

1982 • 228 citations

Stimulation of basophil and rat mast cell histamine release by eosinophil granule-derived cationic proteins.

1984 • 227 citations

A Study of Survivals in Hodgkin's Disease Treated Radiologically

1950 • 223 citations

Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia

1990 • 220 citations

Rare Occurrence of Classical Hodgkin's Disease as a T Cell Lymphoma

2000 • 217 citations

1 The epidemiology of Hodgkin's disease

1996 • 215 citations

Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed-Sternberg cells of classic Hodgkin disease

2000 • 214 citations

Radioimmunoassay of human eosinophil cationic protein (ECP) by an improved method. Establishment of normal levels in serum and turnover in vivo

1991 • 204 citations

Tumor Necrosis Factor Receptor-associated Factor (TRAF) 5 and TRAF2 Are Involved in CD30-mediated NFκB Activation

1997 • 204 citations

Hodgkin's disease: Complications of therapy and excess mortality

1997 • 204 citations

Whole-body positron emission tomography using 18F-fluorodeoxyglucose compared to standard procedures for staging patients with Hodgkin's disease.

2001 • 202 citations

Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

2001 • 200 citations

BEACOPP, a new dose-escalated and accelerated regimen, is at least as effective as COPP/ABVD in patients with advanced-stage Hodgkin's lymphoma: interim report from a trial of the German Hodgkin's Lymphoma Study Group.

1998 • 199 citations

Eosinophil cationic protein/RNase 3 is another RNase A-family ribonuclease with direct antiviral activity

1998 • 194 citations

Eosinophil infiltration of human colonic carcinomas as a prognostic indicator.

1983 • 193 citations

Frequent expression of interleukin-10 by Epstein-Barr virus-harboring tumor cells of Hodgkin's disease

1996 • 193 citations

Hodgkin's Disease in Siblings

1977 • 184 citations

REVIEW OF BRITISH NATIONAL LYMPHOMA INVESTIGATION STUDIES OF HODGKIN'S DISEASE AND DEVELOPMENT OF PROGNOSTIC INDEX

1985 • 184 citations

Tissue eosinophilia correlates strongly with poor prognosis in nodular sclerosing Hodgkin's disease, allowing for known prognostic factors

2000 • 184 citations

In vitro killing of microfilariae of Brugia pahangi and Brugia malayi by eosinophil granule proteins.

1990 • 180 citations

MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease.

1985 • 178 citations

Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease

1995 • 175 citations

Interleukin-9 expression in human malignant lymphomas: unique association with Hodgkin's disease and large cell anaplastic lymphoma

1991 • 173 citations

Alternating versus hybrid MOPP and ABVD combinations in advanced Hodgkin's disease: ten-year results.

1996 • 173 citations

Cytochemical, immunologic, chromosomal, and molecular genetic analysis of a novel cell line derived from Hodgkin's disease

1986 • 171 citations

Radiation therapy versus combination chemotherapy in the treatment of early-stage Hodgkin's disease: seven-year results of a prospective randomized trial.

1991 • 171 citations

18FDG-PET following treatment as valid predictor for disease-free survival in Hodgkin’s lymphoma

2001 • 171 citations

Prognostic factors among 185 adults with newly diagnosed advanced Hodgkin's disease treated with alternating potentially noncross-resistant chemotherapy and intermediate-dose radiation therapy.

1990 • 168 citations

Eosinophils from patients with blood eosinophilia express transforming growth factor beta 1

1991 • 168 citations

Relationship of histopathologic features to survival and relapse in nodular sclerosing Hodgkin's disease. A study of 1659 patients

1989 • 165 citations

Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways.

1995 • 164 citations

Hodgkin's disease: Establishment and characterization of four in vitro cell lines

1981 • 162 citations

Chemokines, cytokines and their receptors in Hodgkin's lymphoma cell lines and tissues

2002 • 160 citations

Prognostic significance of mediastinal involvement in Hodgkin's disease treated with curative radiotherapy

1980 • 157 citations

Establishment and characteristics of two unique cell lines from patients with lymphosarcoma

1974 • 154 citations

BEACOPP: An intensified chemotherapy regimen in advanced Hodgkin's disease

1997 • 153 citations

Biology of Hodgkin's lymphoma

2002 • 152 citations

Hodgkin/Reed-Sternberg Cells Induce Fibroblasts to Secrete Eotaxin, a Potent Chemoattractant for T Cells and Eosinophils

1999 • 152 citations

Human eosinophils synthesize and secrete interleukin-6, in vitro

1992 • 152 citations

Phase III Randomized Intergroup Trial of Subtotal Lymphoid Irradiation Versus Doxorubicin, Vinblastine, and Subtotal Lymphoid Irradiation for Stage IA to IIA Hodgkin’s Disease

2001 • 148 citations

Epstein-Barr virus DNA is abundant and monoclonal in the Reed-Sternberg cells of Hodgkin's disease: association with mixed cellularity subtype and Hispanic American ethnicity

1994 • 147 citations

Arginine-rich cationic proteins of human eosinophil granules: comparison of the constituents of eosinophilic and neutrophilic leukocytes.

1977 • 147 citations

Whole-body positron emission tomography using 18F-fluorodeoxyglucose for initial staging of patients with Hodgkin's disease

2001 • 145 citations

Risk of Hodgkin's Disease and Other Cancers After Infectious Mononucleosis

2000 • 144 citations

Thoracic irradiation in hodgkin's disease: disease control and long-term complications

1990 • 142 citations

Differential Chemokine Expression in Tissues Involved by Hodgkin’s Disease: Direct Correlation of Eotaxin Expression and Tissue Eosinophilia

1999 • 142 citations

The Transcription Factor PU.1, Necessary for B-Cell Development Is Expressed in Lymphocyte Predominance, But Not Classical Hodgkin’s Disease

2001 • 142 citations

Activated Cytotoxic T Cells as Prognostic Marker in Hodgkin's Disease

1997 • 138 citations

Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line

1996 • 137 citations

Adverse clinical outcome in Hodgkin's disease is associated with loss of retinoblastoma protein expression, high Ki67 proliferation index, and absence of Epstein-Barr virus-latent membrane protein 1 expression.

1997 • 132 citations

Epidemiology of Hodgkin's disease

1972 • 130 citations

Problems in Hodgkin’s Disease Management

1999 • 128 citations

Late Medical Complications and Fatigue in Hodgkin’s Disease Survivors

2001 • 128 citations

Prognostic factors in 454 cases of Hodgkin's disease.

1971 • 127 citations

Differential Chemokine Expression in Tissues Involved by Hodgkin’s Disease: Direct Correlation of Eotaxin Expression and Tissue Eosinophilia

1999 • 125 citations

Hodgkin's disease derived cell lines HDLM-2 and L-428: Comparison of morphology, immunological and isoenzyme profiles

1986 • 119 citations

Hodgkin's and Non-Hodgkin's Lymphomas.

1981 • 116 citations

Interleukin-9 and its receptor: involvement in mast cell differentiation and T cell oncogenesis

1995 • 116 citations

Phagocytic and Tumor Necrosis Factor Alpha Response of Human Mast Cells following Exposure to Gram-Negative and Gram-Positive Bacteria

1998 • 116 citations

Extended versus involved fields irradiation combined with MOPP chemotherapy in early clinical stages of Hodgkin's disease.

1985 • 115 citations

Localization of the guinea pig eosinophil major basic protein to the core of the granule

1978 • 113 citations

Enhancement of factor XII dependent reactions by eosinophil cationic protein

1979 • 111 citations

Eosinophil granule proteins activate human heart mast cells.

1996 • 110 citations

Serum levels of soluble CD30 are elevated in the majority of untreated patients with Hodgkin's disease and correlate with clinical features and prognosis.

1994 • 110 citations

CASES OF SARCOMA AND OF HODGKIN'S DISEASE TREATED BY EXPOSURES TO X-RAYS—A PRELIMINARY REPORT.

1902 • 105 citations

A numerical prognostic index for clinical use in identification of poor-risk patients with Hodgkin's disease at diagnosis

1991 • 101 citations

Interaction between host T cells and Reed–Sternberg cells in Hodgkin lymphomas

2000 • 100 citations

The pathologic and clinical heterogeneity of lymphocyte-depleted Hodgkin's disease.

1986 • 99 citations

The Importance of the Eosinophil in Head and Neck Cancer

1992 • 98 citations

Social class and age at diagnosis of Hodgkin's disease: new epidemiologic evidence for the "two-disease hypothesis".

1982 • 98 citations

Problems in Hodgkin’s Disease Management

1999 • 95 citations

Serum Level of the Soluble Form of the CD30 Molecule Identifies Patients With Hodgkin's Disease at High Risk of Unfavorable Outcome

1998 • 94 citations

Morphologic, immunologic, enzymehistochemical and chromosomal analysis of a cell line derived from Hodgkin's disease. Evidence for a B-cell origin of sternberg-reed cells

1985 • 93 citations

Mast cells and tumors. The specific enhancement of tumor proliferation in vitro.

1985 • 92 citations

Mast cell-tumor cell interactions: for or against tumour growth and metastasis?

1997 • 92 citations

Inducible loss of NF-κB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes

2000 • 92 citations

Infiltration of eosinophils in Hodgkin's disease involved lymph nodes predicts prognosis

1993 • 89 citations

Purification and characterization of a new cationic protein--eosinophil protein-X (EPX)--from granules of human eosinophils.

1983 • 89 citations

Interleukin 9 is expressed by primary and cultured Hodgkin and Reed-Sternberg cells.

1992 • 89 citations

Mortality in Relation to Histologic Type in Hodgkin’s Disease

1956 • 88 citations

The cytotoxic eosinophil cationic protein (ECP) has ribonuclease activity

1986 • 87 citations

Identification of interleukin-2 in human peripheral blood eosinophils.

1996 • 85 citations

Eosinophil cationic protein alters proteoglycan metabolism in human lung fibroblast cultures.

1992 • 84 citations

Treatment outcome in Hodgkin's disease in patients above the age of 60: A population-based study

1991 • 84 citations

Immunohistochemical evidence of a role for transforming growth factor beta in the pathogenesis of nodular sclerosing Hodgkin's disease.

1990 • 84 citations

ChlVPP/EVA Hybrid Versus the Weekly VAPEC-B Regimen for Previously Untreated Hodgkin’s Disease

2002 • 83 citations

Tumor Necrosis Factor Receptor-Associated Factor 1 Is Overexpressed in Reed-Sternberg Cells of Hodgkin’s Disease and Epstein-Barr Virus-Transformed Lymphoid Cells

1999 • 83 citations

Purification and characterization of eosinophil cationic protein from normal human eosinophils

1988 • 81 citations

Human eosinophils express messenger RNA encoding RANTES and store and release biologically active RANTES protein

1996 • 81 citations

Stage I to IIB Hodgkin's disease: the combined experience at Stanford University and the Joint Center for Radiation Therapy.

1987 • 80 citations

Epstein–barr virus in hodgkin disease relation to age and subtype

1993 • 80 citations

Influence of mediastinal adenopathy on site and frequency of relapse in patients with Hodgkin's disease.

1982 • 78 citations

Supradiaphragmatic hodgkin's disease: Significance of large mediastinal masses

1980 • 78 citations

Ultrastructural immunogold localization of tumor necrosis factor-alpha to the matrix compartment of eosinophil secondary granules in patients with idiopathic hypereosinophilic syndrome.

1993 • 77 citations

Eosinophils are the major source of transforming growth factor-beta 1 in nodular sclerosing Hodgkin's disease.

1993 • 77 citations

Stanford-Kaiser Permanente G1 study for clinical stage I to IIA Hodgkin's disease: subtotal lymphoid irradiation versus vinblastine, methotrexate, and bleomycin chemotherapy and regional irradiation.

1997 • 77 citations

CD30 ligand expression in nonmalignant and Hodgkin's disease-involved lymphoid tissues.

1996 • 76 citations

Assessment of bone marrow histology in Hodgkin's disease: correlation with clinical factors

1982 • 74 citations

Reevaluation of prognostic significance of symptoms in Hodgkin's disease

1985 • 71 citations

Cultivated H-RS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95

2000 • 71 citations

Immunoperoxidase and enzyme-histochemical demonstration of human skin tryptase in cutaneous mast cells in normal and mastocytoma skin

1988 • 70 citations

Epstein-Barr Virus Distribution in Hodgkin's Disease in an Unselected Swedish Population

1999 • 69 citations

The achievements of the EORTC Lymphoma Group

2002 • 69 citations

The Bactericidal/Permeability-Increasing Protein (BPI) Is Present in Specific Granules of Human Eosinophils

1998 • 68 citations

Late complications after Hodgkin's disease

1996 • 67 citations

Brief chemotherapy (Stanford V) and adjuvant radiotherapy for bulky or advanced Hodgkin's disease: An update

1996 • 66 citations

Mast cells, eosinophils and fibrosis

1997 • 66 citations

The disappearance of prognostic factors in Hodgkin's disease

2002 • 65 citations

Histopathologic grading of nodular sclerosis hodgkin's disease: Lack of prognostic significance in 254 surgically staged patients

1994 • 65 citations

Frequent expression of IL-7 gene transcripts in tumor cells of classical Hodgkin's disease.

1995 • 63 citations

Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines.

1994 • 62 citations

Effects of interleukin (IL)‐13 on immediate‐early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL‐4

1995 • 62 citations

Long-Term Complications of Laparotomy in Hodgkinʼs Disease

1994 • 62 citations

Infiltration of Th1 and Th2 lymphocytes around Hodgkin and Reed‐Sternberg (H&RS) cells in Hodgkin disease: Relation with expression of CXC and CC chemokines on H&RS cells

2002 • 62 citations

A novel domain in the CD30 cytoplasmic tail mediates NFkappaB activation.

1998 • 59 citations

The PACE (population-adjusted clinical epidemiology) strategy: a new approach to multi-centred clinical research

1997 • 58 citations

Rapidly Alternating COPP/ABV/IMEP Is Not Superior to Conventional Alternating COPP/ABVD in Combination With Extended-Field Radiotherapy in Intermediate-Stage Hodgkin's Lymphoma: Final Results of the German Hodgkin's Lymphoma Study Group Trial HD5

2002 • 57 citations

Hodgkin disease: pharmacologic intervention of the CD40-NFκB pathway by a protease inhibitor

2000 • 57 citations

A randomised study of adjuvant chemotherapy after mantle radiotherapy in supradiaphragmatic Hodgkin's disease PS IA-IIB: A report from the Manchester lymphoma group

1984 • 55 citations

Abundant expression of transforming growth factor-β1 and -β2 by Hodgkin's reed-sternberg cells and by reactive T lymphocytes in Hodgkin's disease

1993 • 55 citations

Untitled

1997 • 54 citations

Biological markers may add to prediction of outcome achieved by the international prognostic score in Hodgkin's disease

2000 • 54 citations

Mast cell accumulation at sites of murine tumor implantation: implications for angiogenesis and tumor metastasis.

1994 • 54 citations

Comparison of intracellular bactericidal activities of human neutrophils and eosinophils

1978 • 53 citations

A population-based study of intensive multi-agent chemotherapy with or without autotransplant for the highest risk Hodgkin's disease patients identified by the Scotland and Newcastle Lymphoma Group (SNLG) prognostic index. A Scotland and Newcastle Lymphoma Group study (SNLG HD III)

2002 • 53 citations

Characterization of the Peroxidase in Human Eosinophils

1980 • 53 citations

ABVD versus Stanford V versus MEC in unfavourable Hodgkin's lymphoma: results of a randomised trial

2002 • 52 citations

Selective peripheral blood eosinophilia associated with survival advantage in Hodgkin's disease (BNLI Report No 31). British National Lymphoma Investigation.

1987 • 51 citations

Sequence Variation at Two Eosinophil-Associated Ribonuclease Loci in Humans

2000 • 51 citations

Five years' experience with Ch1VPP: Effective low-toxicity combination chemotherapy for Hodgkin's disease

1982 • 51 citations

A Numerical Prognostic Index for Clinical use in Identification of Poor-Risk Patients with Hodgkin's Disease at Diagnosis

1992 • 51 citations

High numbers of active caspase 3–positive Reed-Sternberg cells in pretreatment biopsy specimens of patients with Hodgkin disease predict favorable clinical outcome

2002 • 50 citations

Prognostic factors in Hodgkin's disease stage IV

1988 • 49 citations

Presentation of Hodgkin's disease as an endobronchial lesion

1984 • 49 citations

Hodgkin disease: prognostic factors and treatment strategies

2000 • 49 citations

Polymorphism of the eosinophil cationic protein‐gene is related to the expression of allergic symptoms

2002 • 48 citations

Reassessment of prognostic factors in stage IIIA and IIIB Hodgkin's disease treated with MOPP and radiotherapy

1981 • 47 citations

Tissue Eosinophilia in Relation to Immunopathological and Clinical Characteristics in Hodgkin's Disease

2001 • 47 citations

Prognostic factors in Hodgkin's disease

1996 • 47 citations

Interleukin-6, but not interleukin-4, is expressed by Reed-Sternberg cells in Hodgkin's disease with or without histologic features of Castleman's disease.

1992 • 47 citations

Stem cell factor‐dependent human cord blood derived mast cells express α‐ and β‐tryptase, heparin and chondroitin sulphate

1996 • 47 citations

Tumour burden as the main indicator of prognosis in Hodgkin's disease

1992 • 46 citations

Prognosis of bulky Hodgkin's disease treated with chemotherapy alone or combined with radiotherapy.

1985 • 44 citations

Eosinophil Cationic Protein

2001 • 43 citations

Hypereosinophilic syndrome in Hodgkin's disease with increased granulocyte-macrophage colony-stimulating factor

1995 • 42 citations

An analysis of prognostic factors in early stage Hodgkin's disease

1986 • 42 citations

Improved survival in Hodgkin's disease

1976 • 42 citations

Epidemiology and histopathology of Hodgkin's disease in Finland

1977 • 42 citations

Production of multiple cytokines by Hodgkin's disease derived cell lines

1992 • 38 citations

MOPP chemotherapy versus extended-field radiotherapy in the management of pathological stages I-IIA Hodgkin's disease.

1989 • 38 citations

Treatment of Hodgkin's Disease: The Swedish National Care Programme Experience

1996 • 37 citations

Immunoelectron microscopic localization of catalase in human eosinophilic leukocytes.

1982 • 37 citations

The eosinophil granule proteins in serum, but not the oxidative metabolism of the blood eosinophils, are increased in cancer

1997 • 37 citations

Prognostic factors in Hodgkin's lymphoma

2002 • 36 citations

Prognostic Factors in Hodgkin's Disease

1977 • 35 citations

Bulky mediastinal Hodgkin's disease management and prognosis

1984 • 35 citations

Local eosinophilia in stroma of tumors related to prognosis.

1984 • 35 citations

A polymorphism in the hMSH2 gene (gIVS12-6T>C) associated with non-Hodgkin lymphomas

2002 • 35 citations

Long-Term Results From MOPPEBVCAD Chemotherapy With Optional Limited Radiotherapy in Advanced Hodgkin's Disease

1998 • 34 citations

TNF-alpha and IL-6 induce differentiation in the human basophilic leukaemia cell line KU812.

1994 • 32 citations

ABUNDANT EXPRESSION OF CHEMOKINES IN MALIGNANT AND INFECTIVE HUMAN LYMPHADENOPATHIES

1999 • 32 citations

Immortalization of Mouse Bone Marrow-Derived Mast Cells with Ad12-SV40 Virus

1993 • 31 citations

Notre Methode De Roentgentherapie De La Lymphogranulomatoses (Hodgkin): Resultats Eloignes

1931 • 31 citations

Hodgkin’s disease in a national and hospital population: trends over 20 years

1997 • 31 citations

Eosinophil granule proteins inhibit substance P-induced histamine release from human skin mast cells

1994 • 31 citations

Tumor cell concentration and tumor burden in relation to histopathologic subtype and other prognostic factors in early stage Hodgkin's disease

1990 • 30 citations

A Systematic Overview of Chemotherapy Effects in Hodgkin's Disease

2001 • 29 citations

Blood eosinophilia in hodgkin's disease: A follow‐up of 25 cases in Venezuela

1992 • 29 citations

Lymphocyte abnormalities predicting a poor prognosis in Hodgkin's disease. A long-term follow-up

1991 • 29 citations

Prognostic Importance of Pruritus in Hodgkin's Disease

1978 • 29 citations

Soluble vascular cell adhesion molecule‐1 (sVCAM‐1) is an independent prognostic marker in Hodgkin's disease

1998 • 29 citations

A quantitative study of eosinophil polymorphs in Hodgkin's disease.

1984 • 28 citations

Soluble ICAM-1 in Hodgkin's Disease: A Promising Independent Predicitive Marker for Survial

1995 • 27 citations

[The combination of epirubicin, bleomycin, vinblastine and prednisone (EBVP) before radiotherapy in localized stages of Hodgkin's disease. Phase II trials].

1987 • 27 citations

Weekly VAPEC-B chemotherapy for high grade non-Hodgkin's lymphoma: Results of treatment in 184 patients

1994 • 27 citations

Clinical Relevance of Positron Emission Tomography (PET) in Treatment Control and Relapse of Hodgkin's Disease

2001 • 26 citations

Treatment of early and intermediate stages of supradiaphragmatic Hodgkin's disease: The Swedish National Care Programme Experience

1994 • 26 citations

Time Trends and Sex Patterns in Hodgkin’s Disease Incidence in Canada, 1970–1995

2000 • 26 citations

A quantitative study of mast cells in Hodgkin's disease.

1984 • 26 citations

Ultrastructural immunogold localization of interleukin 5 to the crystalloid core compartment of eosinophil secondary granules in patients with atopic asthma.

1996 • 26 citations

Identification and characterization of an Epstein-Barr virus-specific T-cell response in the pathologic tissue of a patient with Hodgkin's disease.

1995 • 25 citations

Treatment of early-stage Hodgkin's disease.

1999 • 25 citations

Lack of prognostic value of histopathologic parameters in Hodgkin's disease, nodular sclerosis type. A study of 123 patients with limited stage disease who had undergone laparotomy and were treated with radiation therapy.

1992 • 24 citations

The Treatment of Hodgkin's Disease.

1970 • 23 citations

Eosinophil cationic protein inhibits immunoglobulin production and proliferation in vitro in human plasma cells

1992 • 23 citations

Laparotomy Versus No Laparotomy in the Management of Early-Stage, Favorable-Prognosis Hodgkin's Disease: A Decision Analysis

1999 • 23 citations

Transactions of the pathological society of London

1854 • 22 citations

Polymorphisms within glutathione S-transferase genes in pediatric non-Hodgkin's lymphoma.

2002 • 21 citations

Late relapse after treatment for clinical Stage I and II Hodgkin's disease

1997 • 21 citations

Treatment outcome in patients younger than 60 years with advanced stages (IIB–IV) of Hodgkin's disease: the Swedish National Health Care Programme experience

2000 • 21 citations

Is Hodgkin's disease an infectious disease?

1994 • 21 citations

Chemotherapy of Hodgkin’s lymphoma with alternating cycles of COPP (cyclophosphamide, vincristin, procarbazine, prednisone) and ABVD (doxorubicin, bleomycin, vinblastine and dacarbazine). Results of the HD1 and HD3 trials of the German Hodgkin Study Group

1989 • 20 citations

New treatments for Hodgkin’s disease

2002 • 18 citations

Current clinical trials for the treatment of advanced‐stage Hodgkin's disease: BEACOPP

2002 • 18 citations

Prognostic Significance of Large Mediastinal Involvement in Hodgkin's Disease

1983 • 18 citations

The Alcohol‐intolerance Syndrome in Hodgkin's Disease

1959 • 18 citations

Eosinophil Predominance in Hodgkin's Disease

1977 • 18 citations

Mast cell reactivity in lymphoma: a preliminary communication.

1992 • 17 citations

Clinical drug‐resistant nodular sclerosing Hodgkin's lymphoma is associated with decreased bcl‐2 expression in the surrounding lymphocytes and with increased bcl‐2 expression in the Reed–Sternberg cells

2000 • 17 citations

British National Lymphoma Investigation: Pilot Studies of Neoadjuvant Chemotherapy in Clinical Stage Ia and IIa Hodgkin's Disease

2001 • 16 citations

High molecular weight transforming growth factor beta is excreted in the urine in active nodular sclerosing Hodgkin's disease.

1992 • 15 citations

Epidemiological Study of Hodgkin’s Disease in Cuba and Sweden

1990 • 15 citations

Immune deficiency in family members of patients with Hodgkin's disease

1990 • 15 citations

The Johns Hopkins Hospital Reports.

1897 • 13 citations

Monocytes, but not macrophages, produce the eosinophil cationic protein

2001 • 13 citations

Cultivated H-RS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95

2000 • 13 citations

The Original Illustrations of Hodgkin's Disease

1968 • 13 citations

Incidence and clinical importance of bone marrow eosinophilia in Hodgkin's disease (BNLI Report No 29). British National Lymphoma Investigation.

1987 • 13 citations

A population‐based study of the outcome for patients with first relapse of Hodgkin's lymphoma

2002 • 12 citations

Increased blood clearance rate of indium-111 oxine-labeled autologous CD4+ blood cells in untreated patients with Hodgkin's disease

1990 • 11 citations

Late sequelae of treatment of Hodgkin's disease

1997 • 11 citations

Inhibition of ongoing immunoglobulin production by eosinophil cationic protein

1992 • 10 citations

Monocytes, but not macrophages, produce the eosinophil cationic protein

2001 • 10 citations

Long-term outcome of treatment for ann arbor Stage I Hodgkin's disease: Prognostic factors for survival and freedom from progression

1997 • 10 citations

IS THE ALCOHOL-INTOLERANCE SYNDROME IN HODGKIN'S DISEASE DISAPPEARING?

1972 • 9 citations

Early-stage hodgkin’s disease

2001 • 7 citations

The Second International Symposium on Hodgkin's Disease. Workshop I: Review on prognostic factors.

1992 • 7 citations

Summary of informal discussion on the prognostic and therapeutic implications of staging in Hodgkin's disease.

1971 • 7 citations

Polymorphic tumor necrosis factors microsatellite TNFa4 is associated with resistance of Hodgkin lymphoma to chemotherapy and with replapses after therapy.

2002 • 6 citations

Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Etoposide (CHOPE) for Advanced-Stage Hodgkin's Disease: CALGB 8856

2001 • 6 citations

Eosinophil cationic protein : expression levels and polymorphisms.

2002 • 6 citations

7a Management of early stage Hodgkin's disease: the role of radiation therapy and/or chemotherapy

1996 • 4 citations

Serum Levels of Soluble CD 30 and Their Relationship to Tumour Burden and Prognosis in Patients with Hodgkin's Disease

1997 • 2 citations

Thomas Hodgkin: Social activist

2000 • 2 citations

Hodgkin's disease: a clinicopathologic study.

1995 • 2 citations

Hodgkin Lymphoma : Studies of Advanced Stages, Relapses and the Relation to Non-Hodgkin Lymphomas

2002 • 2 citations

Alcohol-induced pain in tuberculous adenitis.

1993 • 2 citations

Signal Transduction in Mast Cell Migration

2001 • 1 citations

THIS WEEK IN SCIENCE

1992 • 1 citations

[Mastocytosis--two diseases with different physiopathology].

2002 • 1 citations