The function of leak and kuzbanian during growth cone and cell migration

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

Slit Proteins Bind Robo Receptors and Have an Evolutionarily Conserved Role in Repulsive Axon Guidance

1999 • 1,155 citations

Slit Is the Midline Repellent for the Robo Receptor in Drosophila

1999 • 930 citations

Roundabout Controls Axon Crossing of the CNS Midline and Defines a Novel Subfamily of Evolutionarily Conserved Guidance Receptors

1998 • 882 citations

RETRACTED: A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion

1999 • 686 citations

Mutations affecting growth cone guidance in drosophila: Genes necessary for guidance toward or away from the midline

1993 • 677 citations

The Embryonic Development of Drosophila melanogaster

1997 • 661 citations

Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding

1999 • 558 citations

cAMP-Dependent Growth Cone Guidance by Netrin-1

1997 • 550 citations

Regulated Cleavage of a Contact-Mediated Axon Repellent

2000 • 522 citations

Directional guidance of neuronal migration in the olfactory system by the protein Slit

1999 • 517 citations

Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis

1997 • 516 citations

slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.

1990 • 499 citations

Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1

1999 • 478 citations

Genetic analysis of growth cone guidance in drosophila: Fasciclin II functions as a neuronal recognition molecule

1991 • 464 citations

Repulsive Axon Guidance

2000 • 434 citations

Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian

1999 • 413 citations

Calcium signalling in the guidance of nerve growth by netrin-1

2000 • 380 citations

Slit proteins: key regulators of axon guidance, axonal branching, and cell migration

2000 • 356 citations

KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

1996 • 331 citations

Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

1998 • 328 citations

Short-Range and Long-Range Guidance by Slit and Its Robo Receptors

2000 • 301 citations

Dosage-Sensitive and Complementary Functions of Roundabout and Commissureless Control Axon Crossing of the CNS Midline

1998 • 300 citations

Molecular basis of semaphorin-mediated axon guidance

2000 • 300 citations

The Mouse SLIT Family: Secreted Ligands for ROBO Expressed in Patterns That Suggest a Role in Morphogenesis and Axon Guidance

1999 • 288 citations

slit: An EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system

1988 • 281 citations

Phospholipase C-γ and Phosphoinositide 3-Kinase Mediate Cytoplasmic Signaling in Nerve Growth Cone Guidance

1999 • 281 citations

The Conserved Immunoglobulin Superfamily Member SAX-3/Robo Directs Multiple Aspects of Axon Guidance in C. elegans

1998 • 280 citations

Selecting a Longitudinal Pathway

2000 • 275 citations

commissureless Controls Growth Cone Guidance across the CNS Midline in Drosophila and Encodes a Novel Membrane Protein

1996 • 260 citations

Chemorepulsion of Neuronal Migration by Slit2 in the Developing Mammalian Forebrain

1999 • 250 citations

Structural features of a superfamily of zinc-endopeptidases: the metzincins

1995 • 236 citations

Short-Range and Long-Range Guidance by Slit and Its Robo Receptors

2000 • 230 citations

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

2000 • 216 citations

Crossing the Midline

2000 • 192 citations

Chimeric Axon Guidance Receptors

1999 • 190 citations

The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila

1996 • 183 citations

DCC and netrins

1998 • 137 citations

Control of cell behaviour by signalling through Eph receptors and ephrins

2000 • 135 citations

Axon repulsion from the midline of the Drosophila CNS requires slit function

1999 • 132 citations

Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo

2000 • 116 citations

Commissure Formation in the Embryonic CNS ofDrosophila

1999 • 112 citations

Complex Proteolytic Processing Acts on Delta, a Transmembrane Ligand for Notch, duringDrosophilaDevelopment

1998 • 103 citations

Semaphorin Signaling

1999 • 87 citations

Commissure formation in the embryonic CNS of Drosophila II. Function of the different midline cells

1999 • 64 citations

CNS midline cells in Drosophila induce the differentiation of lateral neural cells

1997 • 42 citations

Calmodulin and Son of sevenless dependent signaling pathways regulate midline crossing of axons in the Drosophila CNS

2000 • 41 citations

Effects ofroundabouton Growth Cone Dynamics, Filopodial Length, and Growth Cone Morphology at the Midline and throughout the Neuropile

1999 • 39 citations

Axon guidance: Netrin receptors are revealed

1997 • 27 citations