Hypoxic up-regulation of erythroid 5-aminolevulinate synthase
Data up to Jan 2025
Total Citations Per Year
Abstract
References (27)
Cellular adaptation to hypoxia: O2‐sensing protein hydroxylases, hypoxia‐inducible transcription factors, and O2‐regulated gene expression
2002 • 1,114 citations
Desferrioxamine induces erythropoietin gene expression and hypoxia- inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction
1993 • 740 citations
The transferrin receptor: role in health and disease
1999 • 567 citations
Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences
1995 • 553 citations
Oxygen-regulated Transferrin Expression Is Mediated by Hypoxia-inducible Factor-1
1997 • 400 citations
Identification of a Hypoxia Response Element in the Transferrin Receptor Gene
1999 • 359 citations
Role of Hypoxia-inducible Factor-1 in Transcriptional Activation of Ceruloplasmin by Iron Deficiency
2000 • 275 citations
Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs.
1994 • 273 citations
The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1)DNA recognition site
1995 • 228 citations
Enzymatic defect in "X-linked" sideroblastic anemia: molecular evidence for erythroid delta-aminolevulinate synthase deficiency.
1992 • 164 citations
Human δ-aminolevulinate synthase: Assignment of the housekeeping gene to 3p21 and the erythroid-specific gene to the X chromosome
1990 • 162 citations
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 • 147 citations
X-linked Pyridoxine-Responsive Sideroblastic Anemia Due to a Thr388-to-Ser Substitution in Erythroid 5-Aminolevulinate Synthase
1994 • 127 citations
General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia‐inducible factor 1α
1999 • 122 citations
Identification and Characterization of a Conserved Erythroid-specific Enhancer Located in Intron 8 of the Human 5-Aminolevulinate Synthase 2 Gene
1998 • 91 citations
Regulation of erythroid 5-aminolevulinate synthase expression during erythropoiesis
1999 • 88 citations
Dissecting hypoxia‐dependent and hypoxia‐independent steps in the HIF‐1α activation cascade: implications for HIF‐1α gene therapy
2001 • 83 citations
Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation
2000 • 80 citations
Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation
2000 • 76 citations
Molecular regulation of 5-aminolevulinate synthase. Diseases related to heme biosynthesis.
1990 • 66 citations
Expression of mammalian 5-aminolevulinate synthase in Escherichia coli. Overproduction, purification, and characterization.
1993 • 58 citations
The Mouse Gene for Hypoxia‐Inducible Factor‐1α
1997 • 48 citations
Transcriptional regulation of the murine erythroid-specific 5-aminolevulinate synthase gene
2000 • 41 citations
The role of the erythroid-specific delta-aminolevulinate synthase gene expression in erythroid heme synthesis
1995 • 35 citations
Oxygen tension modulates β‐globin switching in embryoid bodies
1999 • 30 citations
The role of the erythroid-specific delta-aminolevulinate synthase gene expression in erythroid heme synthesis
1995 • 26 citations
Hypoxic Upregulation of TNF Receptor Type 2 Expression Involves NF-IL-6 and Is Independent of HIF-1 or HIF-2
2001 • 19 citations