5-Lipoxygenase Binds Calcium

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Measurement of protein-binding phenomena by gel filtration

1962 • 1,275 citations

Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins

1994 • 1,113 citations

Detection of Calcium Binding Proteins by 45Ca Autoradiography on Nitrocellulose Membrane after Sodium Dodecyl Sulfate Gel Electrophoresis1

1984 • 772 citations

5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes.

1993 • 397 citations

Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187.

1988 • 323 citations

Crystal Structure of a Calcium-Phospholipid Binding Domain from Cytosolic Phospholipase A2

1998 • 268 citations

5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation.

1995 • 192 citations

Ca2+ Signaling and Intracellular Ca2+ Binding Proteins

1996 • 138 citations

Translocation and Leukotriene Synthetic Capacity of Nuclear 5-Lipoxygenase in Rat Basophilic Leukemia Cells and Alveolar Macrophages

1995 • 133 citations

Isolation and characterization of a cDNA clone encoding rat 5-lipoxygenase.

1988 • 132 citations

Kinetic mechanism of guinea pig neutrophil 5-lipoxygenase.

1986 • 114 citations

Reversible translocation of 5-lipoxygenase in mast cells upon IgE/antigen stimulation.

1993 • 97 citations

Investigation of the mechanism of non‐turnover‐dependent inactivation of purified human 5‐lipoxygenase

1992 • 77 citations

Ca2(+)-induced conformational changes and location of Ca2+ transport sites in sarcoplasmic reticulum Ca2(+)-ATPase as detected by the use of proteolytic enzyme (V8).

1990 • 67 citations

Reversible membrane association of neutrophil 5-lipoxygenase is accompanied by retention of activity and a change in substrate specificity.

1992 • 65 citations

Mutations at the C-Terminal Isoleucine and Other Potential Iron Ligands of 5-Lipoxygenase

1995 • 63 citations

Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors.

1991 • 49 citations

The involvement of extracellular calcium in the formation of 5‐lipoxygenase metabolites by human polymorphonuclear leukocytes

1991 • 44 citations

Interactions of proteins with polymeric materials

1956 • 41 citations

Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages

1998 • 34 citations

Interfacial kinetic reaction of human 5‐lipoxygenase

1994 • 25 citations

Polymorphonuclear leukocytes

2009 • 3 citations