Correlation between protein kinase C activity and histopathological criteria in human colorectal adenoma

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The evolution of cancer of the colon and rectum

1975 • 2,120 citations

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

1979 • 1,139 citations

The National Polyp Study

1990 • 820 citations

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

1984 • 643 citations

Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine.

1980 • 568 citations

The phorbol ester receptor: a phospholipid-regulated protein kinase

1985 • 522 citations

[The role of protein kinase C in cell surface signal transduction and tumor promotion].

1986 • 508 citations

Abnormal pattern of cell proliferation in the entire colonic mucosa of patients with colon adenoma or cancer

1987 • 311 citations

Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene

1987 • 303 citations

The evolution of cancer of the colon and rectum

2010 • 234 citations

Characterization of phorbol ester receptors and their down-modulation in GH4C1 rat pituitary cells.

1981 • 142 citations

Altered levels of protein kinase C and Ca2+-dependent protein kinases in human colon carcinomas.

1987 • 126 citations

Growth factors, oncogenes, and multistage carcinogenesis

1987 • 121 citations

Altered protein kinase C activity in biopsies of human colonic adenomas and carcinomas.

1991 • 117 citations

Tyrosine kinase activity in breast cancer, benign breast disease, and normal breast tissue.

1989 • 105 citations

Cells that overproduce protein kinase C are more susceptible to transformation by an activated H-ras oncogene.

1989 • 93 citations

1,2-Dimethylhydrazine-induced alterations in protein kinase C activity in the rat preneoplastic colon.

1990 • 60 citations

Protein kinase C activity as marker for colorectal cancer

1991 • 45 citations

Altered protein tyrosine kinase levels in human colon carcinoma

1991 • 12 citations

Cells That Overproduce Protein Kinase C Are More Susceptible to Transformation by an Activated H-ras Oncogene

1989 • 11 citations