Protein kinase C activity as marker for colorectal cancer

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

1984 • 643 citations

Abnormal pattern of cell proliferation in the entire colonic mucosa of patients with colon adenoma or cancer

1987 • 311 citations

Phase 1 and phase 2 proliferative lesions of colonic epithelial cells in diseases leading to colonic cancer

1974 • 259 citations

Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures

1976 • 250 citations

Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation and reactive oxygen formation by bile acids.

1987 • 199 citations

Pattern of epithelial cell proliferation in colorectal mucosa of normal subjects and of patients with adenomatous polyps or cancer of the large bowel.

1988 • 164 citations

[24] Assay and purification of protein kinase C

1986 • 159 citations

Characterization of phorbol ester receptors and their down-modulation in GH4C1 rat pituitary cells.

1981 • 142 citations

Production of diacylglycerol, an activator of protein kinase C, by human intestinal microflora.

1990 • 132 citations

Altered levels of protein kinase C and Ca2+-dependent protein kinases in human colon carcinomas.

1987 • 126 citations

Classification and risk assessment of individuals with familial polyposis, Gardner's syndrome, and familial non-polyposis colon cancer from [3H]thymidine labeling patterns in colonic epithelial cells.

1984 • 106 citations

Study of Human Rectal Epithelial Cells <italic>In Vitro</italic>. II. H<sup>3</sup>-Thymidine Incorporation Into Polyps and Adjacent Mucosa<xref ref-type="fn" rid="FN1">2</xref>

1966 • 101 citations

Cells that overproduce protein kinase C are more susceptible to transformation by an activated H-ras oncogene.

1989 • 93 citations

Involvement of protein kinase C activation in ornithine decarboxylase gene expression in primary culture of newborn mouse epidermal cells and in skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.

1986 • 72 citations

1,2-Dimethylhydrazine-induced alterations in protein kinase C activity in the rat preneoplastic colon.

1990 • 60 citations

Subcellular distribution of protein kinase C in rat colonic epithelial cells with different proliferative activities.

1987 • 39 citations

Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas

1990 • 36 citations

Low diacylglycerol values in colonic adenomas and colorectal cancer.

1990 • 20 citations

Comparative studies on phosphorylation of synthetic peptide analogue of ribosomal protein S6 and 40‐S ribosomal subunits between Ca^{2 +}/phospholipid‐dependent protein kinase and its protease‐activated form

1987 • 20 citations

Altered protein tyrosine kinase levels in human colon carcinoma

1991 • 12 citations