Targeting T cell responses by selective chemokine receptor expression

Dendritic cells and the control of immunity

1998 • 14,345 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

1993 • 1,427 citations

Follicular B Helper T Cells Express Cxc Chemokine Receptor 5, Localize to B Cell Follicles, and Support Immunoglobulin Production

2000 • 1,379 citations

Cxc Chemokine Receptor 5 Expression Defines Follicular Homing T Cells with B Cell Helper Function

2000 • 1,188 citations

A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen

1996 • 1,125 citations

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

2003 • 1,058 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

NKT cells: facts, functions and fallacies

2000 • 875 citations

The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

1999 • 839 citations

Gamma/Delta Cells

1993 • 819 citations

CCL27–CCR10 interactions regulate T cell–mediated skin inflammation

2002 • 773 citations

γδ T cells: functional plasticity and heterogeneity

2002 • 773 citations

Visualization of Specific B and T Lymphocyte Interactions in the Lymph Node

1998 • 762 citations

Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining

2002 • 758 citations

The unconventional lifestyle of NKT cells

2002 • 756 citations

Chemokines and the Tissue-Specific Migration of Lymphocytes

2002 • 692 citations

Lymphocyte Trafficking and Regional Immunity

1999 • 686 citations

Lymphocyte Cc Chemokine Receptor 9 and Epithelial Thymus-Expressed Chemokine (Teck) Expression Distinguish the Small Intestinal Immune Compartment

2000 • 620 citations

Subspecialization of Cxcr5+ T Cells

2001 • 590 citations

Distinct Functional Lineages of Human Vα24 Natural Killer T Cells

2002 • 567 citations

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

2002 • 558 citations

The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.

1991 • 557 citations

Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

1990 • 533 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

CXCL13 Is Required for B1 Cell Homing, Natural Antibody Production, and Body Cavity Immunity

2002 • 521 citations

Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: The multistep model confirmed and refined

1995 • 520 citations

CC Chemokine Receptor (CCR)4 and the CCR10 Ligand Cutaneous T Cell–attracting Chemokine (CTACK) in Lymphocyte Trafficking to Inflamed Skin

2001 • 502 citations

Human G Protein–Coupled Receptor Gpr-9-6/Cc Chemokine Receptor 9 Is Selectively Expressed on Intestinal Homing T Lymphocytes, Mucosal Lymphocytes, and Thymocytes and Is Required for Thymus-Expressed Chemokine–Mediated Chemotaxis

1999 • 492 citations

Rapid Acquisition of Tissue-specific Homing Phenotypes by CD4+ T Cells Activated in Cutaneous or Mucosal Lymphoid Tissues

2002 • 490 citations

In Vivo–Activated Cd4 T Cells Upregulate Cxc Chemokine Receptor 5 and Reprogram Their Response to Lymphoid Chemokines

1999 • 482 citations

Rules of chemokine receptor association with T cell polarization in vivo

2001 • 472 citations

Molecular Mechanisms of Lymphocyte Homing to Peripheral Lymph Nodes

1998 • 469 citations

Prominence of γδ T cells in the ruminant immune system

1991 • 427 citations

The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules

2000 • 420 citations

Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype.

1999 • 359 citations

Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes.

1994 • 350 citations

CCR7 Expression and Memory T Cell Diversity in Humans

2001 • 342 citations

Rapid leukocyte integrin activation by chemokines

2002 • 341 citations

The Role of Thymus-Expressed Chemokine and Its Receptor CCR9 on Lymphocytes in the Regional Specialization of the Mucosal Immune System

2000 • 336 citations

Cytokines and chemoattractants in allergic inflammation

2002 • 330 citations

CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells

2003 • 328 citations

Cutting Edge: The Orphan Chemokine Receptor G Protein-Coupled Receptor-2 (GPR-2, CCR10) Binds the Skin-Associated Chemokine CCL27 (CTACK/ALP/ILC)

2000 • 327 citations

A Role for CCR9 in T Lymphocyte Development and Migration

2002 • 321 citations

Chemokine Up-Regulation and Activated T Cell Attraction by Maturing Dendritic Cells

1999 • 315 citations

CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa

2002 • 313 citations

Intestinal dendritic cells increase T cell expression of α4β7 integrin

2002 • 309 citations

Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis

1999 • 306 citations

The Role of Chemokines in the Microenvironmental Control of T versus B Cell Arrest in Peyer's Patch High Endothelial Venules

2000 • 298 citations

Cutting Edge: Activation of NK T Cells by CD1d and α-Galactosylceramide Directs Conventional T Cells to the Acquisition of a Th2 Phenotype

1999 • 296 citations

Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among Vα24+Vβ11+ NKT cell subsets with distinct cytokine-producing capacity

2002 • 293 citations

Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

2001 • 291 citations

Differential expression of homing-associated adhesion molecules by T cell subsets in man.

1990 • 270 citations

Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells.

1996 • 265 citations

Expression of the G-protein--coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells

1994 • 260 citations

CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa

2002 • 258 citations

Cutting Edge: Developmental Switches in Chemokine Responses During T Cell Maturation

1999 • 247 citations

Expression of the Chemokine Receptors CCR4, CCR5, and CXCR3 by Human Tissue-Infiltrating Lymphocytes

2002 • 244 citations

CD1d-restricted Help To B Cells By Human Invariant Natural Killer T Lymphocytes

2003 • 242 citations

A Common Mucosal Chemokine (Mucosae-Associated Epithelial Chemokine/CCL28) Selectively Attracts IgA Plasmablasts

2003 • 238 citations

Chemokines in rapid leukocyte adhesion triggering and migration

2002 • 237 citations

Integrating Conflicting Chemotactic Signals

1999 • 220 citations

CD1d-restricted Human Natural Killer T Cells Are Highly Susceptible to Human Immunodeficiency Virus 1 Infection

2002 • 217 citations

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

1989 • 217 citations

Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells

1989 • 215 citations

Expression of the G-protein--coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells

1994 • 214 citations

The Role of β7 Integrins in CD8 T Cell Trafficking During an Antiviral Immune Response

1999 • 211 citations

C-C Chemokine Receptor 4 Expression Defines a Major Subset of Circulating Nonintestinal Memory T Cells of Both Th1 and Th2 Potential

2001 • 205 citations

Cutting Edge: CCR7+ and CCR7− Memory T Cells Do Not Differ in Immediate Effector Cell Function

2002 • 204 citations

Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls

1999 • 196 citations

A fundamental subdivision of circulating lymphocytes defined by adhesion to mucosal addressin cell adhesion molecule-1. Comparison with vascular cell adhesion molecule-1 and correlation with beta 7 integrins and memory differentiation.

1996 • 191 citations

Pivotal Role of Dendritic Cell–derived CXCL10 in the Retention of T Helper Cell 1 Lymphocytes in Secondary Lymph Nodes

2002 • 186 citations

Differential expression of the chemokine receptors by the Th1- and Th2-type effect or populations within circulating CD4+ T cells

2000 • 182 citations

Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo

1999 • 179 citations

Lymphocyte subsets show marked differences in their distribution between blood and the afferent and efferent lymph of peripheral lymph nodes.

1988 • 179 citations

Differential Chemotactic Behavior of Developing T Cells in Response to Thymic Chemokines

1998 • 169 citations

Monocyte Chemoattractant Protein-1-Dependent Increase of Vα14 NKT Cells in Lungs and Their Roles in Th1 Response and Host Defense in Cryptococcal Infection

2001 • 158 citations

Identification of two distinct subsets of bovine γδ T cells with unique cell surface phenotype and tissue distribution

1997 • 154 citations

Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells

2002 • 152 citations

Activated Murine B Lymphocytes and Dendritic Cells Produce a Novel CC Chemokine which Acts Selectively on Activated T Cells

1998 • 151 citations

Expression of mucosal homing receptor alpha4beta7 by circulating CD4+ cells with memory for intestinal rotavirus.

1997 • 149 citations

Separable effector T cell populations specialized for B cell help or tissue inflammation

2001 • 138 citations

Chemoattractant receptor cross talk as a regulatory mechanism in leukocyte adhesion and migration

1997 • 128 citations

Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus

2002 • 124 citations

Understanding the function of CD1-restricted T cells

2003 • 123 citations

Immune Surveillance and Effector Functions of CCR10+ Skin Homing T Cells

2002 • 121 citations

T cell immunity in lymphoid and non-lymphoid tissues

2002 • 117 citations

Differential distribution of γδT-cell receptor lymphocyte subpopulations in blood and spleen of young and adult cattle

1994 • 112 citations

Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus

2002 • 104 citations

Cutting Edge: Induction of Follicular Homing Precedes Effector Th Cell Development

2001 • 103 citations

A homing receptor-bearing cortical thymocyte subset: Implications for thymus cell migration and the nature of cortisone-resistant thymocytes

1984 • 102 citations

CCR7 Ligands, SLC/6Ckine/Exodus2/TCA4 and CKβ-11/MIP-3β/ELC, Are Chemoattractants for CD56+CD16−NK Cells and Late Stage Lymphoid Progenitors

1999 • 101 citations

T-cell subsets: Chemokine receptors guide the way

1998 • 99 citations

Immediate Early Effector Functions of Virus-Specific CD8+CCR7+ Memory Cells in Humans Defined by HLA and CC Chemokine Ligand 19 Tetramers

2003 • 97 citations

T Cell Accumulation in B Cell Follicles Is Regulated by Dendritic Cells and Is Independent of B Cell Activation

2003 • 95 citations

Co-stimulation and selection for T-cell help for germinal centres: the role of CD28 and OX40

2000 • 93 citations

HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV replication and cell death

2000 • 91 citations

The chemokine/chemokine-receptor family: potential and progress for therapeutic intervention

2000 • 85 citations

Circulating CD3+/T cell receptor V gamma 3+ fetal murine thymocytes home to the skin and give rise to proliferating dendritic epidermal T cells.

1991 • 84 citations

Expression of the Mucosal Homing Receptor α₄β₇Correlates with the Ability of CD8⁺Memory T Cells To Clear Rotavirus Infection

1998 • 83 citations

In Vivo Differentiated Cytokine-Producing CD4+ T Cells Express Functional CCR7

2002 • 82 citations

Chemokines in autoimmune diseases

2000 • 73 citations

Transendothelial chemotaxis of human αβ and γδ T lymphocytes to chemokines

1998 • 68 citations

Natural Killer T Cells Restricted by the Monomorphic MHC Class 1b CD1d1 Molecules Behave Like Inflammatory Cells

2002 • 68 citations

A circulating bovine gamma delta T cell subset, which is found in large numbers in the spleen, accumulates inefficiently in an artificial site of inflammation: correlation with lack of expression of E-selectin ligands and L-selectin.

1999 • 67 citations

Pivotal role of CCL25 (TECK)-CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes

2002 • 61 citations

Bovine γδ T Cell Subsets Express Distinct Patterns of Chemokine Responsiveness and Adhesion Molecules: A Mechanism for Tissue-Specific γδ T Cell Subset Accumulation

2002 • 59 citations

α4β7 independent pathway for CD8+ T cell–mediated intestinal immunity to rotavirus

2000 • 59 citations

A Circulating Bovine γδ T Cell Subset, Which Is Found in Large Numbers in the Spleen, Accumulates Inefficiently in an Artificial Site of Inflammation: Correlation with Lack of Expression of E-Selectin Ligands and L-Selectin

1999 • 50 citations

Involvement of CCL25 (TECK) in the generation of the murine small-intestinal CD8? ?+CD3+ intraepithelial lymphocyte compartment

2002 • 50 citations

Preferential tissue localization of bovine γδ T cell subsets defined by anti-T cell receptor for antigen antibodies

1998 • 45 citations

Regulatory role of peritoneal NK1.1+ alpha beta T cells in IL-12 production during Salmonella infection.

1999 • 42 citations

Life-span, recirculation, and transformation of lymphocytes.

1966 • 42 citations

Regulatory Role of Peritoneal NK1.1+αβ T Cells in IL-12 Production DuringSalmonellaInfection

1999 • 37 citations

Chemokines as organizers of primary and secondary lymphoid organs

2003 • 36 citations

Human milk lymphocytes bearing the gamma/delta T-cell receptor are mostly delta TCS1-positive cells.

1991 • 36 citations

Antigen-induced selective sequestration of T lymphocytes: role of the major histocompatibility complex.

1980 • 26 citations

Early appearance of T cell receptor αβ⁺ CD4⁻ CD8⁻ T cells with a skewed variable region repertoire after infection with Listeria monocytogenes

1995 • 22 citations

Selective compartmentalization of γσ‐T lymphocytes in human breastmilk

1997 • 19 citations