γδ T cells: functional plasticity and heterogeneity

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells

1998 • 1,134 citations

γδ Cells: A Right Time and a Right Place for a Conserved Third Way of Protection

2000 • 1,107 citations

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

1999 • 1,006 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Regulation of Cutaneous Malignancy by γδ T Cells

2001 • 945 citations

IMGT, the international ImMunoGeneTics database

2000 • 877 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

1995 • 672 citations

Modulation of Epithelial Cell Growth by Intraepithelial γδ T Cells

1994 • 644 citations

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1990 • 611 citations

Specificity and function of T cells bearing γδ receptors

1988 • 570 citations

Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

1990 • 533 citations

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1993 • 528 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

Recognition of cluster of differentiation 1 antigens by human CD4−CD8>− cytolytic T lymphocyte

1989 • 521 citations

Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire.

1990 • 510 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen

1993 • 426 citations

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

1986 • 423 citations

The nature of major histocompatibility complex recognition by γδ T cells

1994 • 407 citations

Diversity, rearrangement, and expression of murine T cell gamma genes

1986 • 405 citations

MICA Engagement by Human Vγ2Vδ2 T Cells Enhances Their Antigen-Dependent Effector Function

2001 • 394 citations

Evidence for an Interferon-Inducible Gene, Ifi202, in the Susceptibility to Systemic Lupus

2001 • 371 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Recognition of Self Antigens by Skin-Derived T Cells with Invariant γδ Antigen Receptors

1991 • 358 citations

Recognition by Human V _γ 9/V _δ 2 T Cells of a GroEL Homolog on Daudi Burkitt's Lymphoma Cells

1990 • 357 citations

IMGT, the international ImMunoGeneTics database

1999 • 347 citations

Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes

1996 • 315 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

Biological Insights into TCRγδ+ and TCRαβ+ Intraepithelial Lymphocytes Provided by Serial Analysis of Gene Expression (SAGE)

2001 • 267 citations

T Cell Responses Modulated Through Interaction Between CD8αα and the Nonclassical MHC Class I Molecule, TL

2001 • 257 citations

Resident pulmonary lymphocytes expressing the γ/δ T-cell receptor

1989 • 253 citations

Chemokine expression by intraepithelial gamma delta T cells. Implications for the recruitment of inflammatory cells to damaged epithelia.

1996 • 250 citations

Structure of a human γδ T-cell antigen receptor

2001 • 243 citations

Late dominance of the inflammatory process in murine influenza by gamma/delta + T cells.

1990 • 213 citations

Immunoregulatory Functions of γδ T Cells

1998 • 201 citations

Immune protection and control of inflammatory tissue necrosis by gamma delta T cells.

1994 • 189 citations

Immunoregulatory functions for murine intraepithelial lymphocytes: gamma/delta T cell receptor-positive (TCR+) T cells abrogate oral tolerance, while alpha/beta TCR+ T cells provide B cell help.

1992 • 186 citations

A Population of Murine γδ T Cells That Recognize an Inducible MHC Class Ib Molecule

2000 • 183 citations

Specific recognition of staphylococcal enterotoxin A by human T cells bearing receptors with the Vγ9 region

1990 • 175 citations

Essential Requirement of Antigen Presentation by Monocyte Lineage Cells for the Activation of Primary Human γδ T Cells by Aminobisphosphonate Antigen

2001 • 174 citations

T Cell Receptor–γ/δ Cells Protect Mice from Herpes Simplex Virus Type 1–induced Lethal Encephalitis

1997 • 173 citations

Heat shock protein Hsp60-reactive gamma delta cells: a large, diversified T-lymphocyte subset with highly focused specificity.

1992 • 172 citations

Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.

1989 • 168 citations

Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile

2001 • 165 citations

Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell.

1994 • 164 citations

Differential function of intestinal intraepithelial lymphocyte subsets.

1992 • 160 citations

Propagation and regulation of systemic autoimmunity by gammadelta T cells.

1996 • 155 citations

Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia.

1993 • 150 citations

Disease-specific changes in gammadelta T cell repertoire and function in patients with pulmonary tuberculosis.

1996 • 140 citations

Structure and Specificity of a Class II MHC Alloreactive γδ T Cell Receptor Heterodimer

1989 • 133 citations

Role of gamma delta T cells in murine collagen-induced arthritis.

1993 • 126 citations

Crucial role of TCR gamma chain junctional region in prenyl pyrophosphate antigen recognition by gamma delta T cells.

1998 • 122 citations

Gamma delta T cells can recognize nonclassical MHC in the absence of conventional antigenic peptides.

1994 • 122 citations

CD1c as a target recognition structure for human T lymphocytes: Analysis with peripheral blood γ/δ cells

1990 • 120 citations

Downmodulation of the Inflammatory Response to Bacterial Infection by γδ T Cells Cytotoxic for Activated Macrophages

2000 • 118 citations

Conservation of T Cell Receptor Conformation in Epidermal γδ Cells with Disrupted Primary V _γ Gene Usage

1998 • 117 citations

Control of natural killer cell-mediated innate resistance against the intracellular pathogen Listeria monocytogenes by gamma/delta T lymphocytes

1996 • 111 citations

Crucial Role of TCRγ Chain Junctional Region in Prenyl Pyrophosphate Antigen Recognition by γδ T Cells

1998 • 107 citations

Apoptosis of Fashigh CD4+ Synovial T Cells by Borrelia-reactive Fas-ligandhigh γδ T Cells in Lyme Arthritis

1996 • 106 citations

In vivo cytokine production in murine listeriosis. Evidence for immunoregulation by gamma delta+ T cells.

1996 • 106 citations

Involvement of the Fas/Fas ligand pathway in activation-induced cell death of mycobacteria-reactive human gamma delta T cells: a mechanism for the loss of gamma delta T cells in patients with pulmonary tuberculosis.

1998 • 105 citations

Primary gamma delta cell clones can be defined phenotypically and functionally as Th1/Th2 cells and illustrate the association of CD4 with Th2 differentiation.

1998 • 105 citations

Developmentally regulated fetal thymic and extrathymic T-cell receptor gamma delta gene expression.

1990 • 99 citations

Collagen-induced arthritis development requires αβ T cells but not γδ T cells: studies with T cell-deficient (TCR mutant) mice

1999 • 98 citations

Extrathymic origin of human gamma delta T cells during fetal development.

1996 • 97 citations

Selection is not required to produce invariant T-cell receptor γ-gene junctional sequences

1993 • 94 citations

The importance of gd T cells in the resolution of pathogen‐induced inflammatory immune responses

2000 • 93 citations

A murine CD4-, CD8- T cell receptor-gamma delta T lymphocyte clone specific for herpes simplex virus glycoprotein I.

1992 • 89 citations

Depletion of a γδ T Cell Subset Can Increase Host Resistance to a Bacterial Infection

2000 • 86 citations

Heat shock protein Hsp60-reactive γδ cells: a large, diversified Tlymphocyte subset withhighly focused specificity.

1992 • 85 citations

Involvement of the Fas/Fas Ligand Pathway in Activation-Induced Cell Death of Mycobacteria-Reactive Human γδ T Cells: A Mechanism for the Loss of γδ T Cells in Patients with Pulmonary Tuberculosis

1998 • 82 citations

Primary γδ Cell Clones Can Be Defined Phenotypically and Functionally as Th1/Th2 Cells and Illustrate the Association of CD4 with Th2 Differentiation

1998 • 79 citations

Cytokine Production by Vγ⁺-T-Cell Subsets Is an Important Factor Determining CD4⁺-Th-Cell Phenotype and Susceptibility of BALB/c Mice to Coxsackievirus B3-Induced Myocarditis

2001 • 79 citations

Nomenclature for T-cell receptor (TCR) gene segments of the immune system

1995 • 78 citations

Plasma Membrane Expression of Heat Shock Protein 60 In Vivo in Response to Infection

1999 • 76 citations

Dual antigenic recognition by cloned human gamma delta T cells.

1992 • 75 citations

The Generation of Human γδ T Cell Repertoires During Fetal Development

1998 • 73 citations

The generation of human gammadelta T cell repertoires during fetal development.

1998 • 72 citations

Evidence that the same gamma delta T cells respond during infection-induced and autoimmune inflammation.

1997 • 72 citations

Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at positions 152 and 156.

1990 • 71 citations

Functional gamma delta T-lymphocyte defect associated with human immunodeficiency virus infections.

1997 • 71 citations

Functional γδ T-lymphocyte Defect Associated with Human Immunodeficiency Virus Infections

1997 • 64 citations

Bias in the gamma delta T cell response to Listeria monocytogenes. V delta 6.3+ cells are a major component of the gamma delta T cell response to Listeria monocytogenes.

1996 • 60 citations

Cytokine profiles of bronchoalveolar lavage cells from mice with influenza pneumonia: consequences of CD4+ and CD8+ T cell depletion.

1993 • 57 citations

In vivo response of murine gamma delta T cells to a heat shock protein-derived peptide.

1993 • 55 citations

Lyme arthritis synovial gamma delta T cells respond to Borrelia burgdorferi lipoproteins and lipidated hexapeptides.

1998 • 54 citations

Generation of human gammadelta T-cell repertoires.

1999 • 54 citations

Two waves of gamma delta T cells expressing different V delta genes are recruited into schistosome-induced liver granulomas.

1995 • 52 citations

Structural requirements for peptides that stimulate a subset of gamma delta T cells.

1994 • 45 citations

Development of Dendritic Epidermal T Cells with a Skewed Diversity of γδTCRs in Vδ1-Deficient Mice

2000 • 43 citations

T Cell Receptor Specificity Is Critical for the Development of Epidermal γδ T Cells

2001 • 43 citations

Specificity of human T lymphocytes expressing a γ/δ T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a γ/δ clone

1989 • 43 citations

Lyme Arthritis Synovial γδ T Cells Respond toBorrelia burgdorferiLipoproteins and Lipidated Hexapeptides

1998 • 42 citations

Extent of γδ T cell involvement in the pneumonia caused by sendai virus

1992 • 38 citations

Specificity of Human T Lymphocytes Expressing a γ/δT Cell Antigen Receptor. Recognition of a Polymorphic Determinant of HLA Class I Molecules by a γ/δ+ Clone

1991 • 24 citations

Modulation of experimental allergic encephalomyelitis in mice by immunization with a peptide specific for the γδ T cell receptor

1997 • 23 citations

Gene transfer studies of T cell receptor-gamma delta recognition. Specificity for staphylococcal enterotoxin A is conveyed by V gamma 9 alone.

1994 • 21 citations

Generation of Human γδ T-Cell Repertoires

1999 • 20 citations

Activation of γδ T cells by mycobacterial antigens in rheumatoid arthritis

1999 • 16 citations

Selective response of gamma delta T-cell hybridomas to orthomyxovirus-infected cells

1996 • 11 citations