Regulatory Role of Peritoneal NK1.1+αβ T Cells in IL-12 Production DuringSalmonellaInfection

Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

1995 • 2,437 citations

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

1993 • 1,704 citations

Antibodies to interleukin 12 abrogate established experimental colitis in mice.

1995 • 1,338 citations

MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function

1997 • 1,326 citations

Requirement for V _α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

1997 • 1,226 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

1994 • 1,044 citations

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

1997 • 937 citations

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

1994 • 862 citations

CD1d1 Mutant Mice Are Deficient in Natural T Cells That PromptlyProduce IL-4

1997 • 612 citations

Impaired NK1+ T Cell Development and Early IL-4 Production in CD1-Deficient Mice

1997 • 494 citations

A Subset of CD4 ⁺ Thymocytes Selected by MHC Class I Molecules

1994 • 464 citations

Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production.

1995 • 372 citations

CD40 Ligand Is Required for Protective Cell-Mediated Immunity to Leishmania major

1996 • 332 citations

Activation events during thymic selection.

1992 • 326 citations

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice.

1994 • 304 citations

Protective Role of CD40 in Leishmania major Infection at Two Distinct Phases of Cell-Mediated Immunity

1996 • 302 citations

An NK1.1+ CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor V beta family.

1992 • 270 citations

NK1.1⁺ CD4⁺ CD8‐ thymocytes with specific lymphokine secretion

1993 • 265 citations

Predominant expression of invariant V_α14⁺ TCR α chain in NK1.1⁺ T cell populations

1995 • 243 citations

Mouse NK1.1+ T cells: a new family of T cells

1996 • 236 citations

Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes.

1987 • 230 citations

The role of interleukin 12 in the immune response, disease and therapy

1994 • 221 citations

IL-12, But Not IFN-γ, Plays a Major Role in Sustaining the Chronic Phase of Colitis in IL-10-Deficient Mice

1998 • 201 citations

IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection.

1996 • 158 citations

Cutting Edge: Critical Role of NK1+ T Cells in IL-12-Induced Immune Responses In Vivo

1998 • 136 citations

Induction of IFN-γ-producing CD4+ natural killer T cells byMycobacterium bovis bacillus Calmette Guérin

1999 • 126 citations

Murine thymic CD4+ T cell subsets: a subset (Thy0) that secretes diverse cytokines and overexpresses the V beta 8 T cell receptor gene family.

1992 • 115 citations

A pivotal role of IL-12 in T^h1-dependent mouse liver injury

1996 • 101 citations

Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice.

1991 • 101 citations

Induction of gamma/delta T cells in murine salmonellosis by an avirulent but not by a virulent strain of Salmonella choleraesuis.

1992 • 98 citations

Induction of interleukin‐12 p40 transcript by CD40 ligation via activation of nuclear factor‐xB

1997 • 79 citations

Regulation of transforming growth factor‐β production by interleukin‐12

1997 • 77 citations

The role of γδ T cells in priming macrophages to produce tumor necrosis factor‐α

1995 • 74 citations

Evidence of correlation between 50-kilobase plasmid of Salmonella choleraesuis and its virulence

1988 • 74 citations

Expression of an unusual T cell receptor (TCR)-V beta repertoire by Ly-6C+ subpopulations of CD4+ and/or CD8+ thymocytes. Evidence for a developmental relationship between Ly-6C+ thymocytes and CD4-CD8-TCR-alpha beta+ thymocytes.

1991 • 59 citations

Mice deficient in gamma delta T cells are resistant to lethal infection with Salmonella choleraesuis

1995 • 38 citations

Predominant appearance of NK1.1+ T cells producing IL-4 may be involved in the increased susceptibility of mice with the beige mutation during Salmonella infection.

1997 • 30 citations

Different appearance of gamma delta T cells during salmonellosis between Ityr and Itys mice.

1993 • 29 citations

Early appearance of T cell receptor αβ⁺ CD4⁻ CD8⁻ T cells with a skewed variable region repertoire after infection with Listeria monocytogenes

1995 • 22 citations

Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1 beta production in human myeloid leukemia cell lines and peripheral blood mononuclear cells

1994 • 22 citations

Diversity of V gamma gene segments rearranged to the J gamma 4 gene in mice.

1995 • 6 citations