Isoform‐specific associations of CD45 with accessory molecules in human T lymphocytes

Selected methods in cellular immunology

1981 • 1,915 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Selected methods in cellular immunology

1980 • 747 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

1990 • 647 citations

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

1991 • 532 citations

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1989 • 509 citations

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1990 • 466 citations

T cell antigen receptor activation pathways: The tyrosine kinase connection

1991 • 442 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn)

1991 • 395 citations

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

1987 • 327 citations

Protein-tyrosine phosphatases: The other side of the coin

1989 • 308 citations

T-cell memory: the connection between function, phenotype and migration pathways

1991 • 271 citations

T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates

1989 • 258 citations

Is T-cell memory maintained by crossreactive stimulation?

1990 • 253 citations

The synergy between naive and memory T cells during activation

1991 • 247 citations

Structural variants of human T200 glycoprotein (leukocyte-common antigen).

1987 • 239 citations

CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.

1988 • 223 citations

Tyrosine phosphorylation of phospholipase C induced by membrane immunoglobulin in B lymphocytes.

1991 • 205 citations

Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex.

1988 • 180 citations

Antibodies to common leukocyte antigen p220 influence human T cell proliferation by modifying IL 2 receptor expression.

1985 • 164 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck.

1990 • 142 citations

Characterization of CD45 and CD45R monoclonal antibodies using transfected mouse cell lines that express individual human leukocyte common antigens.

1988 • 140 citations

Association of CD2 and CD45 on human T lymphocytes

1990 • 139 citations

Molecular associations on the T cell surface correlate with immunological memory

1990 • 130 citations

Human CD8+ T lymphocytes can be divided into CD45RA+ and CD45RO+ cells with different requirements for activation and differentiation.

1991 • 118 citations

T cell receptor tyrosine phosphorylation. Variable coupling for different activating ligands.

1987 • 90 citations

CD45-protein tyrosine phosphatase cross-linking inhibits T cell receptor CD3-mediated activation in human T cells.

1989 • 85 citations

Alternative use of 5' exons in the specification of Ly-5 isoforms distinguishing hematopoietic cell lineages.

1987 • 82 citations

CD45 cross-linking regulates phospholipase C activation and tyrosine phosphorylation of specific substrates in CD3/Ti-stimulated T cells.

1991 • 74 citations

Fc receptor triggering induces expression of surface activation antigens and release of platelet-activating factor in large granular lymphocytes.

1986 • 65 citations

A second signal for T cell mitogenesis provided by monoclonal antibodies CD45 (T200)

1987 • 64 citations

Interaction between the CD45 antigen and phytohemagglutinin. Inhibitory effect on the lectininduced T cell proliferation by anti‐CD45 monoclonal antibody

1987 • 57 citations

Basal Synthesis of Heat Shock Protein 70 Increases with Age in Rat Kidneys

1997 • 53 citations

Differential expression of the alternatively spliced exons of murine CD45 in T_h1 and T_h2 cell clones

1991 • 51 citations

CD8⁺CD11b⁺ peripheral blood T lymphocytes contain lymphokine‐activated killer cell precursors

1989 • 43 citations

Anti-cd45ra antibodies increase the proliferation of mouse t cells to phytohemagglutinin through the interleukin 2/interleukin 2 receptor pathway

1989 • 24 citations

[42] Use of fluorescent antibodies in the study of lymphoid cell membrane molecules

1984 • 23 citations

Association of CD2 and T200 (CD45) in mouse T lymphocytes

1990 • 23 citations