Molecular associations on the T cell surface correlate with immunological memory

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Human naive and memory T cells

1988 • 793 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Selected methods in cellular immunology

1980 • 747 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

1988 • 716 citations

The isolation and characterization of the human helper inducer T cell subset.

1985 • 708 citations

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.

1983 • 654 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

1985 • 550 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1989 • 509 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Perturbation of the T4 molecule transmits a negative signal to T cells.

1985 • 335 citations

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

1987 • 327 citations

Differential activation requirements for virgin and memory T cells.

1988 • 271 citations

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1989 • 237 citations

CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.

1988 • 223 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen.

1986 • 159 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.

1985 • 145 citations

The role of CD4 in T-cell activation: accessory molecule or co-receptor?

1989 • 134 citations

The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype.

1989 • 125 citations

Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies.

1989 • 103 citations

Alternative use of 5' exons in the specification of Ly-5 isoforms distinguishing hematopoietic cell lineages.

1987 • 82 citations

Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies.

1989 • 72 citations

A second signal for T cell mitogenesis provided by monoclonal antibodies CD45 (T200)

1987 • 64 citations

CD45R gives immunofluorescence and transduces signals on mouse T cells

1988 • 30 citations

Anti-cd45ra antibodies increase the proliferation of mouse t cells to phytohemagglutinin through the interleukin 2/interleukin 2 receptor pathway

1989 • 24 citations

[42] Use of fluorescent antibodies in the study of lymphoid cell membrane molecules

1984 • 23 citations

The required interaction between monocytes and peripheral blood T lymphocytes (T‐PBL) upon activation via CD2 or CD3. Role of HLA class I molecules from accessory cells and the differential response of T‐PBL subsets

1988 • 20 citations

Clonal Expansion and Differentiation to Effector Function in Normal CD4 T Cell Subpopulations

1989 • 3 citations