Differential expression of the alternatively spliced exons of murine CD45 in T_h1 and T_h2 cell clones

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

1987 • 966 citations

Human naive and memory T cells

1988 • 793 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

The isolation and characterization of the human helper inducer T cell subset.

1985 • 708 citations

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.

1983 • 654 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Surface Antigen Expression and Immunoglobulin Gene Rearrangement During Mouse pre‐B Cell Development

1983 • 490 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

1987 • 327 citations

Antigens displayed on murine B lymphocyte precursors.

1981 • 299 citations

Molecular and antigenic heterogeneity of the rat leukocyte‐common antigen from thymocytes and T and B lymphocytes

1985 • 286 citations

Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.

1982 • 265 citations

Structural variants of human T200 glycoprotein (leukocyte-common antigen).

1987 • 239 citations

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1989 • 237 citations

Role of interleukin 1 in the activation of T lymphocytes.

1988 • 231 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Cloned, Ia-restricted T cells that do not produce interleukin 4(IL 4)/B cell stimulatory factor 1(BSF-1) fail to help antigen-specific B cells.

1987 • 209 citations

Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation.

1989 • 185 citations

Autocrine growth of CD4+ T cells. Differential effects of IL-1 on helper and inflammatory T cells.

1988 • 183 citations

Antigen-specific activation of effector macrophages by IFN-gamma producing (TH1) T cell clones. Failure of IL-4-producing (TH2) T cell clones to activate effector function in macrophages.

1989 • 183 citations

Distinct functional phenotypes of cloned Ia-restricted helper T cells.

1985 • 171 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

Cloned helper T cells can kill B lymphoma cells in the presence of specific antigen: Ia restriction and cognate vs. noncognate interactions in cytolysis

1984 • 152 citations

Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule.

1981 • 148 citations

Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC.

1990 • 130 citations

The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype.

1989 • 125 citations

Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis.

1985 • 122 citations

B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing.

1987 • 105 citations

Murine CD4+ T cell subsets defined.

1988 • 102 citations

Human T cell subsets

1987 • 85 citations

Alternative use of 5' exons in the specification of Ly-5 isoforms distinguishing hematopoietic cell lineages.

1987 • 82 citations

Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies.

1989 • 72 citations

Prevention of Diabetes in NOD Mice by Injection of Autoreactive T-Lymphocytes

1989 • 60 citations

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens.

1987 • 51 citations

Developmental sequence of T200 antigen modifications in murine T cells.

1987 • 44 citations

T200 alternate exon use in murine lymphoid cells determined by reverse transcription-polymerase chain reaction.

1989 • 37 citations

CD45R gives immunofluorescence and transduces signals on mouse T cells

1988 • 30 citations

A chicken leukocyte common antigen: biochemical characterization and ontogenetic study

1987 • 28 citations

Prevention of diabetes in NOD mice by injection of autoreactive T-lymphocytes

1989 • 26 citations

Anti-cd45ra antibodies increase the proliferation of mouse t cells to phytohemagglutinin through the interleukin 2/interleukin 2 receptor pathway

1989 • 24 citations