CD8+CD11b+ peripheral blood T lymphocytes contain lymphokine‐activated killer cell precursors

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1).

1981 • 1,411 citations

Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man

1981 • 871 citations

Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens.

1983 • 852 citations

A monoclonal antibody reactive with the human cytotoxic/suppressor T cell subset previously defined by a heteroantiserum termed TH2.

1980 • 719 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

Response of resting human peripheral blood natural killer cells to interleukin 2.

1984 • 616 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.

1987 • 565 citations

Natural Cytotoxic Reactivity of Human Lymphocytes Against a Myeloid Cell Line: Characterization of Effector Cells

1977 • 493 citations

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

1986 • 477 citations

A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes

1987 • 446 citations

Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.

1981 • 397 citations

Two forms of the T-cell receptor γ protein found on peripheral blood cytotoxic T lymphocytes

1987 • 391 citations

The Fc receptor for IgG on human natural killer cells: phenotypic, functional, and comparative studies with monoclonal antibodies.

1984 • 325 citations

Immunochemical Proof That a Novel Rearranging Gene Encodes the T Cell Receptor δ Subunit

1987 • 278 citations

Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.

1982 • 265 citations

Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.

1987 • 252 citations

Characterization of a phenotypically distinct subpopulation of Leu-2+ cells that suppresses T cell proliferative responses.

1983 • 251 citations

Dissection of immunoregulatory subpopulations of T lymphocytes within the helper and suppressor sublineages in man.

1982 • 246 citations

Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen.

1985 • 240 citations

Limiting dilution analysis of the cells of immune system I. The clonal basis of the immune response

1984 • 203 citations

T gamma-lymphoproliferative disease and related disorders in humans and experimental animals: a review of the clinical, cellular, and functional characteristics

1984 • 200 citations

A γ-chain complex forms a functional receptor on cloned human lymphocytes with natural killer-like activity

1987 • 199 citations

Morphologic and phenotypic features of the subpopulation of Leu-2+ cells that suppresses B cell differentiation.

1984 • 196 citations

Human lymphocyte subpopulations identified by using three-color immunofluorescence and flow cytometry analysis: correlation of Leu-2, Leu-3, Leu-7, Leu-8, and Leu-11 cell surface antigen expression.

1984 • 159 citations

T gamma-lymphoproliferative disease and related disorders in humans and experimental animals: a review of the clinical, cellular, and functional characteristics

1984 • 153 citations

Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors.

1983 • 151 citations

Regulation of B cell immunoglobulin secretion by functional subsets of T lymphocytes in man

1980 • 149 citations

Large granular lymphocytes in human peripheral blood: ultrastructural and cytochemical characterization of the granules

1982 • 136 citations

Chronic T cell lymphocytosis: a review of 21 cases

1984 • 133 citations

Leucocyte typing III : white cell differentiation antigens

1987 • 128 citations

Soluble antigen-primed inducer T cells activate antigen-specific suppressor T cells in the absence of antigen-pulsed accessory cells: phenotypic definition of suppressor-inducer and suppressor-effector cells.

1984 • 121 citations

A novel epitope of the LFA-1 antigen which can distinguish killer effector and suppressor cells in human CD8 cells

1987 • 107 citations

Lysis of human solid tumor cells by lymphokine-activated natural killer cells.

1986 • 95 citations

Characterization of cells from invaded lymph nodes in patients with solid tumors. Lymphokine requirement for tumor-specific lymphoproliferative response.

1987 • 91 citations

In vitro production of interleukin 1 by normal and malignant human B lymphocytes.

1986 • 90 citations

Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture.

1988 • 89 citations

Functional analysis of cloned germinal center CD4+ cells with natural killer cell-related features. Divergence from typical T helper cells.

1986 • 86 citations

Immunoregulatory T cell circuits in man. Alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic stimulus.

1983 • 72 citations

Rapidly expanded activated human killer cell clones have strong antitumor cell activity and have the surface phenotype of either T gamma, T-non-gamma, or null cells.

1984 • 70 citations

Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery.

1987 • 65 citations

Hematopoietic stem cells

1986 • 56 citations

Ultrastructural analysis of human natural killer cell activation

1987 • 55 citations

CD11 molecule defines two types of suppressor cells within the T8+ population

1988 • 50 citations

Limiting dilution analysis of cells of the immune system II: What can be learnt?

1984 • 42 citations

Differential expression of ecto-5' nucleotidase activity by functionally and phenotypically distinct subpopulations of human Leu-2+/T8+ lymphocytes.

1986 • 28 citations

Large granular lymphocytes from patients with expanded LGL populations acquire cytotoxic functions and release lymphokines upon in vitro activation

1986 • 28 citations

T suppressor cell growth factor and anti-CD3 antibodies stimulate reciprocal subsets of T lymphocytes.

1987 • 23 citations

Establishment of Tac-negative, interleukin-2-dependent cytotoxic cell lines from large granular lymphocytes (LGL) of patients with expanded LGL populations

1986 • 19 citations

Surface markers of human lymphokine‐activated killer cells and their precursors. Analysis at the population and clonal level

1987 • 18 citations

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