Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Excitotoxity and the NMDA receptor

1987 • 1,053 citations

Blockade of "NMDA" Receptors Disrupts Experience-Dependent Plasticity of Kitten Striate Cortex

1987 • 920 citations

Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists

1990 • 905 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

Anatomical organization of excitatory amino acid receptors and their pathways

1987 • 877 citations

A new type of glutamate receptor linked to inositol phospholipid metabolism

1987 • 743 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

Glutamate activates multiple single channel conductances in hippocampal neurons

1987 • 691 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Microtubule-Associated Proteins: Their Potential Role in Determining Neuronal Morphology

1988 • 599 citations

Microtubule-Associated Proteins

1986 • 559 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

The current excitement in long term potentiation

1988 • 538 citations

Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice

1984 • 531 citations

N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.

1987 • 529 citations

Brief bursts of high-frequency stimulation produce two types of structural change in rat hippocampus.

1980 • 474 citations

Long-lasting morphological changes in dendritic spines of dentate granular cells following stimulation of the entorhinal area

1977 • 450 citations

Coupling of Inositol Phospholipid Metabolism with Excitatory Amino Acid Recognition Sites in Rat Hippocampus

1986 • 444 citations

Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo

1988 • 437 citations

Microtubule-associated proteins and the stimulation of tubulin assembly in vitro

1976 • 434 citations

Light and electron microscopic studies of the distribution of microtubule‐associated protein 2 in rat brain: A difference between dendritic and axonal cytoskeletons

1984 • 424 citations

Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence

1984 • 378 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.

1989 • 318 citations

MAP2 is localized to the dendrites of hippocampal neurons which develop in culture

1984 • 313 citations

Fractionation of Brain Microtubule‐Associated Proteins

1978 • 310 citations

Sustained Dendritic Gradients of Ca ²⁺ Induced by Excitatory Amino Acids in CA1 Hippocampal Neurons

1988 • 301 citations

NMDA receptor antagonists disrupt the retinotectal topographic map

1989 • 293 citations

Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau

1989 • 281 citations

Synaptic correlates of associative potentiation/depression: an ultrastructural study in the hippocampus

1983 • 278 citations

The impact of postsynaptic calcium on synaptic transmission — its role in long-term potentiation

1989 • 274 citations

The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro

1987 • 268 citations

A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization

1983 • 265 citations

Structure and phosphorylation of microtubule-associated protein 2 (MAP 2).

1980 • 235 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution

1986 • 229 citations

Electrophysiology of isolated mammalian CNS preparations

1982 • 226 citations

Interactions between neurofilaments and microtubule-associated proteins: a possible mechanism for intraorganellar bridging.

1982 • 222 citations

Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase.

1984 • 213 citations

A glutamate receptor regulates Ca2+ mobilization in hippocampal neurons.

1988 • 210 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus

1984 • 209 citations

Ketamine—xylazine anaesthesia blocks consolidation of ocular dominance changes in kitten visual cortex

1987 • 206 citations

Ca²⁺, Calmodulin‐Dependent Regulation of Microtubule Formation via Phosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin, and Comparison with the Cyclic AMP‐Dependent Phosphorylation

1985 • 183 citations

MAP2 is a component of crossbridges between microtubules and neurofilaments in the neuronal cytoskeleton: quick-freeze, deep-etch immunoelectron microscopy and reconstitution studies

1988 • 182 citations

Excitatory Amino Acid Agonist‐Antagonist Interactions at 2‐Amino‐4‐Phosphonobutyric Acid‐Sensitive Quisqualate Receptors Coupled to Phosphoinositide Hydrolysis in Slices of Rat Hippocampus

1988 • 181 citations

Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II

1989 • 175 citations

Dephosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin by Calcineurin

1985 • 173 citations

The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay

1986 • 172 citations

Molecular Aspects of Cellular Regulation

1986 • 168 citations

Microtubule assembly using the microtubule‐associated protein MAP‐2 prepared in defined states of phosphorylation with protein kinase and phosphatase

1983 • 163 citations

Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus

1988 • 147 citations

Extensive cAMP-dependent and cAMP-independent phosphorylation of microtubule-associated protein 2.

1983 • 146 citations

Ontogeny of microtubule-associated protein 2 in rat cerebellum: Differential expression of the doublet polypeptides

1984 • 144 citations

The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.

1987 • 138 citations

Regional distribution of calcium- and cyclic adenosine 3':5'- monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems

1983 • 136 citations

Ontogenetic changes in the cyclic adenosine 3',5'-monophosphate- stimulatable phosphorylation of cat visual cortex proteins, particularly of microtubule-associated protein 2 (MAP 2): effects of normal and dark rearing and of the exposure to light

1985 • 132 citations

Calcium‐Induced Inactivation of Microtubule Formation in Brain Extracts

1978 • 126 citations

Microtubule-associated protein 2 and tubulin are differently distributed in the dendrites of developing neurons

1986 • 125 citations

Dephosphorylation of Microtubule Proteins by Brain Protein Phosphatases 1 and 2A, and Its Effect on Microtubule Assembly

1988 • 119 citations

Interaction of microtubule-associated protein 2 with actin filaments

1986 • 119 citations

Phosphorylation of Microtubule-Associated Proteins (MAPs) and pH of the Medium Control Interaction between MAPs and Actin Filaments1

1981 • 117 citations

Phosphorylation of tubulin and microtubule-associated proteins by the purified insulin receptor kinase.

1985 • 104 citations

Calcium/phospholipid-dependent kinase recognizes sites in microtubule-associated protein 2 which are phosphorylated in living brain and are not accessible to other kinases.

1986 • 95 citations

Distribution of MAP 2 in dendritic spines and its colocalization with actin

1989 • 95 citations

Numerous phosphates of microtubule-associated protein 2 in living rat brain.

1987 • 87 citations

Colocalization of microtubule-associated protein 1A and microtubule-associated protein 2 on neuronal microtubules in situ revealed with double-label immunoelectron microscopy.

1987 • 84 citations

Purified protein kinase C phosphorylates microtubule-associated protein 2.

1986 • 82 citations

Phosphorylation of Microtubule‐Associated Protein 2 at Distinct Sites by Calmodulin‐Dependent and Cyclic‐AMP‐Dependent Kinases

1985 • 76 citations

Disassembly of microtubules by the action of calmodulin-dependent protein kinase (kinase II) which occurs only in the brain tissues

1983 • 72 citations

Fura-2 measurements of cultured rat Purkinje neurons show dendritic localization of Ca2+ influx

1989 • 66 citations

Amino acid receptors and uptake systems in the mammalian central nervous system.

1988 • 61 citations

Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms

1989 • 52 citations

Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms

1989 • 44 citations

Regulation of the interaction of actin filaments with microtubule-associated protein 2 by calmodulin-dependent protein kinase II

1988 • 40 citations

The sites at which brain microtubule-associated protein 2 is phosphorylated in vivo differ from those accessible to cAMP-dependent kinase in vitro.

1985 • 37 citations

Evidence for the presence of high‐M_r microtubule‐associated proteins and their Ca²⁺‐dependent proteolysis in synaptosomal cytosol

1982 • 30 citations