Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: Peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Microtubule-Associated Proteins: Their Potential Role in Determining Neuronal Morphology

1988 • 599 citations

Microtubule-Associated Proteins

1986 • 559 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence

1984 • 378 citations

Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2, in rat brain

1984 • 326 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture

1980 • 306 citations

Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum.

1985 • 301 citations

Microcentrifuge desalting: A rapid, quantitative method for desalting small amounts of protein

1980 • 294 citations

Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.

1979 • 284 citations

Differential expression of distinct microtubule-associated proteins during brain development.

1985 • 255 citations

A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2)

1981 • 243 citations

Heterogeneity of microtubule-associated protein 2 during rat brain development.

1984 • 236 citations

Structure and phosphorylation of microtubule-associated protein 2 (MAP 2).

1980 • 235 citations

Interactions between neurofilaments and microtubule-associated proteins: a possible mechanism for intraorganellar bridging.

1982 • 222 citations

Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase.

1984 • 213 citations

Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.

1987 • 212 citations

Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems.

1983 • 198 citations

Ca²⁺, Calmodulin‐Dependent Regulation of Microtubule Formation via Phosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin, and Comparison with the Cyclic AMP‐Dependent Phosphorylation

1985 • 183 citations

Troponin C-like proteins (calmodulins) from mammalian smooth muscle and other tissues

1979 • 177 citations

Regulation by steroid hormones of phosphorylation of specific protein common to several target organs.

1976 • 160 citations

Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases.

1984 • 153 citations

Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.

1984 • 151 citations

Extensive cAMP-dependent and cAMP-independent phosphorylation of microtubule-associated protein 2.

1983 • 146 citations

Ontogeny of microtubule-associated protein 2 in rat cerebellum: Differential expression of the doublet polypeptides

1984 • 144 citations

Regional distribution of calcium- and cyclic adenosine 3':5'- monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems

1983 • 143 citations

Regional distribution of calcium- and cyclic adenosine 3':5'- monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems

1983 • 136 citations

Phosphorylation of tubulin and microtubule-associated proteins by the purified insulin receptor kinase.

1985 • 104 citations

Phosphorylation of microtubule-associated protein 2 by calmodulin-dependent protein kinase (Kinase II) which occurs only in the brain tissues

1982 • 103 citations

Calcium/phospholipid-dependent kinase recognizes sites in microtubule-associated protein 2 which are phosphorylated in living brain and are not accessible to other kinases.

1986 • 95 citations

Purified protein kinase C phosphorylates microtubule-associated protein 2.

1986 • 82 citations

Phosphorylation of Microtubule‐Associated Protein 2 at Distinct Sites by Calmodulin‐Dependent and Cyclic‐AMP‐Dependent Kinases

1985 • 76 citations

Disassembly of microtubules by the action of calmodulin-dependent protein kinase (kinase II) which occurs only in the brain tissues

1983 • 72 citations

Possibility of shape conformers of the protein inhibitor of the cyclic adenosine monophosphate-dependent protein kinase

1979 • 71 citations

Electrophoretic separation of nervous system proteins on exponential gradient polyacrylamide gels

1975 • 71 citations

Microheterogeneity of microtubule-associated proteins, MAP-1 and MAP-2, and differential phosphorylation of individual subcomponents.

1985 • 52 citations

Partial Sequence of MAP2 in the Region of a Shared Epitope with Alzheimer Neuronbrillary Tangles

1988 • 50 citations

Regulation of the interaction of actin filaments with microtubule-associated protein 2 by calmodulin-dependent protein kinase II

1988 • 40 citations

Stoichiometry of microtubule-associated protein (MAP2): tubulin and the localisation of the phosphorylation and cysteine residues along the MAP2 primary sequence

1984 • 39 citations

The sites at which brain microtubule-associated protein 2 is phosphorylated in vivo differ from those accessible to cAMP-dependent kinase in vitro.

1985 • 37 citations