HIV-1 Protease Inhibitors Are Substrates for theMDR1 Multidrug Transporter

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

1990 • 1,063 citations

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

1995 • 984 citations

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein.

1989 • 606 citations

GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTER

1995 • 469 citations

Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor

1996 • 411 citations

HIV‐1, macrophages, glial cells, and cytokines in AIDS nervous system disease

1991 • 359 citations

Role of Mononuclear Phagocytes in the Pathogenesis of Human Immunodeficiency Virus Infection

1990 • 277 citations

P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

1997 • 249 citations

Brain Microvascular and Astrocyte Localization of P‐Glycoprotein

1997 • 146 citations

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

1992 • 114 citations

Molecular Biology of Membrane Transport Disorders

1996 • 110 citations

Photoaffinity probes for the alpha 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein.

1990 • 108 citations

Decreased biotolerability for ivermectin and cyclosporin a in mice exposed to potent P‐glycoprotein inhibitors

1995 • 73 citations

Heterogeneity in P‐glycoprotein (multidrug resistance) activity among murine peripheral T cells: Correlation with surface phenotype and effector function

1994 • 34 citations