The mechanism of action of α-naphthoflavone as an inhibitor of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions

1980 • 827 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

STUDIES ON THE MECHANISM OF ACTION OF THE CHLORINATED DIBENZO‐p‐DIOXINS AND RELATED COMPOUNDS*

1979 • 336 citations

Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements

1987 • 323 citations

The Regulation of Cytochrome P-450 Gene Expression

1986 • 283 citations

The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1987 • 251 citations

Alpha-Naphthoflavone: An Inhibitor of Hydrocarbon Cytotoxicity and Microsomal Hydroxylase

1969 • 185 citations

The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

1982 • 184 citations

Autoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P₁450 gene

1985 • 174 citations

The examination and quantitation of tissue cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using hydroxylapatite

1982 • 168 citations

Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme induction and immunotoxicity

1987 • 120 citations

2,2′,4,4′,5,5′-Hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL6J mice

1989 • 105 citations

Dose-response immunotoxicities of commercial polychlorinated biphenyls (PCBs) and their interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1989 • 96 citations

Immunosuppressive activities of polychlorinated dibenzofuran congeners: Quantitative structure-activity relationships and interactive effects

1988 • 95 citations

Aroclor 1254 as an antagonist of the teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin

1987 • 91 citations

Comparative antiestrogenic activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8-trichlorodibenzofuran in the female rat

1988 • 86 citations

6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities.

1988 • 73 citations

Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies.

1989 • 58 citations

6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6 mice

1989 • 57 citations

Dioxin-Inducible Enhancer Region Upstream from the Mouse P₁450 Gene and Interaction with a Heterologous SV40 Promoter

1986 • 53 citations

Polychlorinated dibenzofurans as 2,3,7,8-tcdd antagonists: In vitro inhibition of monooxygenase enzyme induction

1986 • 50 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced porphyria in genetically inbred mice: Partial antagonism and mechanistic studies

1989 • 46 citations

1-amino-3,7,8-trichlorodibenzo-P-dioxin: A specific antagonist for TCDD-induced myelotoxicity

1986 • 30 citations

Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: Mechanistic studies using radiolabeled congeners

1989 • 30 citations

Metabolism of α-naphthoflavone by rat, mouse, rabbit, and hamster liver microsomes

1984 • 10 citations