Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Statistical principles in experimental design.

1962 • 27,228 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

1991 • 982 citations

Nitric oxide synthase: Aspects concerning structure and catalysis

1994 • 865 citations

ROLE OF REVERSIBLE OXIDATION-REDUCTION OF ENZYME THIOLS-DISULFIDES IN METABOLIC REGULATION

1985 • 840 citations

Nitric oxide synthase is a cytochrome P-450 type hemoprotein

1992 • 617 citations

NO+, NO , and NO− Donation by S-Nitrosothiols: Implications for Regulation of Physiological Functions by S-Nitrosylation and Acceleration of Disulfide Formation

1995 • 601 citations

The Nitric Oxide Synthase Family of Proteins

1994 • 465 citations

Nitric oxide and lung disease.

1993 • 445 citations

Negative feedback regulation of endothelial cell function by nitric oxide.

1993 • 371 citations

Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical.

1992 • 344 citations

Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding.

1993 • 302 citations

Reaction of nitric oxide with heme proteins and model compounds of hemoglobin

1987 • 252 citations

N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.

1989 • 245 citations

Neuronal Nitric Oxide Synthase Self-inactivates by Forming a Ferrous-Nitrosyl Complex during Aerobic Catalysis

1995 • 195 citations

Inhibition by nitric oxide of the repair protein, O⁶-DNA-methyltransferase

1994 • 195 citations

Cysteine 184 of endothelial nitric oxide synthase is involved in heme coordination and catalytic activity.

1994 • 117 citations

Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment.

1991 • 110 citations

Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide

1995 • 97 citations

Cysteine 99 of Endothelial Nitric Oxide Synthase (NOS-III) Is Critical for Tetrahydrobiopterin-Dependent NOS-III Stability and Activity

1995 • 86 citations

Oxidation of critical cysteine residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin.

1994 • 84 citations

Methylene blue competes with paraquat for reduction by flavo-enzymes resulting in decreased superoxide production in the presence of heme proteins

1988 • 78 citations

Acrolein-Induced Injury to Cultured Pulmonary Artery Endothelial Cells

1993 • 57 citations

Sulfhydryl-disulfide modulation and the role of disulfide oxidoreductases in regulation of the catalytic activity of nitric oxide synthase in pulmonary artery endothelial cells.

1995 • 52 citations

Nitric oxide preferentially stimulates auto‐ADP‐ribosylation of glyceraldehyde‐3‐phosphate dehydrogenase compared to alcohol or lactate dehydrogenase

1993 • 36 citations

Effect of nitric oxide gas on the generation of nitric oxide by isolated blood vessels: implications for inhalation therapy

1994 • 33 citations

Sulfhydryl-depleting agents, but not deferoxamine, modulate EDRF action in cultured pulmonary arterial cells

1993 • 11 citations