Cysteine 184 of endothelial nitric oxide synthase is involved in heme coordination and catalytic activity.

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1991 • 15,563 citations

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Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

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Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

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Nitric oxide synthase structure and mechanism

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Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.

1992 • 1,004 citations

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

1991 • 982 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.

1993 • 845 citations

Nitric oxide synthase is a cytochrome P-450 type hemoprotein

1992 • 617 citations

Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.

1992 • 616 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase.

1992 • 477 citations

Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein.

1991 • 458 citations

Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer.

1993 • 411 citations

Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide.

1992 • 368 citations

Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical.

1992 • 344 citations

Evidence for a bidomain structure of constitutive cerebellar nitric oxide synthase.

1994 • 201 citations

Brain nitric oxide synthase is a haemoprotein

1992 • 151 citations

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Heme coordination and structure of the catalytic site in nitric oxide synthase.

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Novel exogenous heme-dependent expression of mammalian cytochrome P450 using baculovirus

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Identification and characterization of human immunodeficiency virus type 1 gag-pol fusion protein in transfected mammalian cells

1991 • 32 citations