Critical Roles of a Cyclic AMP Responsive Element and an E-box in Regulation of Mouse Renin Gene Expression

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Morphology, physiology, and molecular biology of renin secretion

1990 • 610 citations

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

1995 • 578 citations

A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos

1998 • 502 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Molecular biology of the renin-angiotensin system.

1993 • 403 citations

Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.

1988 • 391 citations

Transcription Factors Responsive to cAMP

1995 • 379 citations

Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei.

1988 • 276 citations

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1990 • 221 citations

Cell Signaling Switches HOX-PBX Complexes from Repressors to Activators of Transcription Mediated by Histone Deacetylases and Histone Acetyltransferases

2000 • 198 citations

The Adenovirus Major Late Transcription Factor Activates the Rat γ-Fibrinogen Promoter

1987 • 177 citations

Control of a Genetic Regulatory Network by a Selector Gene

2001 • 172 citations

Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct.

1990 • 163 citations

The major late transcription factor binds to and activates the mouse metallothionein I promoter.

1987 • 160 citations

Upstream Stimulatory Factor Binding to the E-box at −65 Is Required for Insulin Regulation of the Fatty Acid Synthase Promoter

1997 • 151 citations

Signal transduction and gene control: the cAMP pathway.

1992 • 142 citations

Cellular control of renin secretion

2005 • 124 citations

Expression of Murine Renin Genes during Fetal Development

1990 • 119 citations

Structure, expression, and regulation of the murine renin genes.

1991 • 115 citations

Role of Proximal Promoter Elements in Regulation of Renin Gene Transcription

1996 • 113 citations

Evidence that the transcription factor USF is a component of the human beta-globin locus control region heteromeric protein complex.

1993 • 88 citations

LXRα functions as a cAMP-responsive transcriptional regulator of gene expression

2000 • 83 citations

Identification of the promoter sequences involved in the cell specific expression of the rat somatostatin gene

1987 • 82 citations

Transactivation of the Human Renin Promoter by the Cyclic AMP/Protein Kinase A Pathway Is Mediated by Both cAMP-responsive Element Binding Protein-1 (CREB)-dependent and CREB-independent Mechanisms in Calu-6 Cells

1997 • 73 citations

Juxtaglomerular Cells

1963 • 68 citations

Retinoic Acid-mediated Activation of the MouseRenin Enhancer

2001 • 68 citations

Expression of a renin/GFP transgene in mouse embryonic, extra-embryonic, and adult tissues

2000 • 65 citations

Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice

1990 • 65 citations

An Abd-B Class HOX·PBX Recognition Sequence Is Required for Expression from the Mouse Ren-1 Gene

2001 • 60 citations

Transcriptional Regulation of the Transforming Growth Factor-β2 Promoter by cAMP-responsive Element-binding Protein (CREB) and Activating Transcription Factor-1 (ATF-1) Is Modulated by Protein Kinases and the Coactivators p300 and CREB-binding Protein

1999 • 60 citations

Participation of upstream stimulator factor (USF) in cadmium-induction of the mouse metallothionein-I gene

1998 • 60 citations

Conserved Enhancer Elements in Human and Mouse Renin Genes Have Different Transcriptional Effects in As4.1 Cells

1997 • 59 citations

Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor

1991 • 55 citations

Binding of Upstream Stimulatory Factor and a Cell-specific Activator to the Calcitonin/Calcitonin Gene-related Peptide Enhancer

1997 • 55 citations

A HOX complex, a repressor element and a 50 bp sequence confer regional specificity to a DPP-responsive enhancer

2001 • 48 citations

Allele-specific Expression of the Murine Ren-1 Genes

1989 • 47 citations

Species-Specific Differences in Positive and Negative Regulatory Elements in the Renin Gene Enhancer

1999 • 47 citations

Inhibition of the Transcription of CYP1A1 Gene by the Upstream Stimulatory Factor 1 in Rabbits

1997 • 45 citations

Transcription of the Transforming Growth Factor-β2 Gene Is Dependent on an E-box Located between an Essential cAMP Response Element/Activating Transcription Factor Motif and the TATA Box of the Gene

1996 • 42 citations

Gs protein mutations and pituitary tumors: Functional correlates and possible therapeutic implications

1996 • 38 citations

Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression.

1993 • 38 citations

Close physical linkage of the murine Ren-1 and Ren-2 loci

1988 • 38 citations

Physical characterization of genetic rearrangements at the mouse renin loci.

1990 • 35 citations

Upstream Stimulatory Factor 1 Regulates Osteopontin Expression in Smooth Muscle Cells

1999 • 34 citations

Mechanism of cAMP regulation of renin gene transcription by proximal promoter.

1994 • 34 citations

Differential activation of the SMαA promoter in smooth vs. skeletal muscle cells by bHLH factors

1999 • 30 citations

Downregulation of Renin Gene Expression by Interleukin-1

1997 • 24 citations

Transcriptional activation of the F1F0 ATP synthase α-subunit initiator element by USF2 is mediated by p300

1999 • 23 citations

Upstream stimulatory factor 2 stimulates transcription through an initiator element in the mouse cytochrome c oxidase subunit Vb promoter

2000 • 20 citations

Cloning and Characterization of the 5′-Flanking Region for the Human Topoisomerase III Gene

1998 • 16 citations

Interleukin-1 inhibits renin gene expression in As4.1 cells but not in native juxtaglomerular cells

1998 • 15 citations

Gs protein mutations and the pathogenesis and function of pituitary tumors

1996 • 13 citations