Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

1987 • 236 citations

Characterization of a bipartite activator domain in transcription factor CREB

1990 • 228 citations

Cyclic AMP responsiveness of human gonadotropin-alpha gene transcription is directed by a repeated 18-base pair enhancer. Alpha-promoter receptivity to the enhancer confers cell-preferential expression.

1987 • 216 citations

Atrial natriuretic peptide inhibits renin release from juxtaglomerular cells by a cGMP-mediated process.

1986 • 213 citations

CAT vectors for analysis of eukaryotic promoters and enhancers

1986 • 184 citations

Purification of the c-fos enhancer-binding protein.

1987 • 156 citations

The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription.

1988 • 127 citations

[50] Proteases in Escherichia coli

1981 • 125 citations

alpha-Adrenergic regulation of secretion of mouse saliva rich in nerve growth factor.

1976 • 111 citations

Molecular cloning of two distinct renin genes from the DBA/2 mouse.

1982 • 90 citations

Tissue-specific regulation of renin expression in the mouse.

1987 • 90 citations

Ren-1 and Ren-2 loci are expressed in mouse kidney.

1985 • 88 citations

Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes.

1989 • 79 citations

A cAMP-responsive Element Regulates Expression of the Mouse Steroid 11β-Hydroxylase Gene

1989 • 76 citations

Tropical climatic phase lags and Earth's precession cycle

1986 • 55 citations

Hypersecretion of submandibular saliva in male mice: Trophic response in small intestine

1983 • 48 citations

Evidence for a cAMP-dependent nuclear factor capable of interacting with a specific region of a eukaryotic gene.

1988 • 17 citations

Electron microscopic immunostaining of nerve growth factor: Secretagogue stimulated submandibular glands

1987 • 10 citations