Induction of antigen-specific human CD4+ T cell anergy by peripheral blood DC2 precursors

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood

1999 • 2,255 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

1999 • 1,912 citations

Induction of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells

2000 • 1,577 citations

Antigen-Specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells

2001 • 1,384 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Induction of tolerance by IL-10-treated dendritic cells.

1997 • 1,263 citations

Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization

2000 • 804 citations

Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

1995 • 756 citations

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood

1996 • 696 citations

Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.

1994 • 626 citations

Models of T cell anergy: is there a common molecular mechanism?

1996 • 575 citations

Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation.

1993 • 569 citations

Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells

2000 • 560 citations

Mobilizing Dendritic Cells for Tolerance, Priming, and Chronic Inflammation

1999 • 474 citations

Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors

1997 • 432 citations

Flt3-Ligand and Granulocyte Colony-Stimulating Factor Mobilize Distinct Human Dendritic Cell Subsets In Vivo

2000 • 419 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Human peripheral blood contains two distinct lineages of dendritic cells

1999 • 380 citations

COSTIMULATORY MOLECULE-DEFICIENT DENDRITIC CELL PROGENITORS (MHC CLASS II+, CD80dim, CD86-) PROLONG CARDIAC ALLOGRAFT SURVIVAL IN NONIMMUNOSUPPRESSED RECIPIENTS12

1996 • 378 citations

A CD1a+/CD11c+ Subset of Human Blood Dendritic Cells Is a Direct Precursor of Langerhans Cells

1999 • 334 citations

Type I IFN Modulates Innate and Specific Antiviral Immunity

2000 • 276 citations

Survival, Maturation, and Function of CD11c− and CD11c+ Peripheral Blood Dendritic Cells Are Differentially Regulated by Cytokines

1999 • 242 citations

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer.

1992 • 224 citations

Culture of bone marrow cells in GM-CSF plus high doses of lipopolysaccharide generates exclusively immature dendritic cells which induce alloantigen- specific CD4 T cell anergyin vitro

2000 • 122 citations

Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo.

1995 • 121 citations

Dendritic cells: development, function and potential use for cancer immunotherapy

1999 • 105 citations

Transfer of dendritic cells (DC)ex vivostimulated with interferon-gamma (IFN-γ) down-modulates autoimmune diabetes in non-obese diabetic (NOD) mice

1999 • 102 citations

Plasmacytoid T cells: A cell population normally present in the reactive lymph node

1988 • 82 citations

Highly restricted TCR-alpha beta usage by autoreactive human T cell clones specific for DNA topoisomerase I: recognition of an immunodominant epitope.

1997 • 61 citations

Mechanisms of central and peripehral T‐cell tolerance: lessons from experimental models of multiple sclerosis

1999 • 58 citations

Analysis of Soluble and Cell Surface Factors Regulating Anti-DNA Topoisomerase I Autoantibody Production Demonstrates Synergy Between Th1 and Th2 Autoreactive T Cells

2000 • 37 citations

Dendritic cells in experimental allergic encephalomyelitis and multiple sclerosis

1999 • 36 citations

Detection of Anti-DNA Topoisomerase I Antibody by an Enzyme-Linked Immunosorbent Assay Using Overlapping Recombinant Polypeptides

1995 • 30 citations