Transfer of dendritic cells (DC)ex vivostimulated with interferon-gamma (IFN-γ) down-modulates autoimmune diabetes in non-obese diabetic (NOD) mice

Dendritic cells and the control of immunity

1998 • 14,345 citations

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

1997 • 1,536 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

1995 • 1,120 citations

The Pathogenesis of Insulin-Dependent Diabetes Mellitus

1994 • 1,077 citations

Prediction of Type I Diabetes in First-Degree Relatives Using a Combination of Insulin, GAD, and ICA512bdc/IA-2 Autoantibodies

1996 • 788 citations

The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD

1997 • 685 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1987 • 576 citations

The Murine Autoimmune Diabetes Model: NOD and Related Strains

1992 • 498 citations

Acceleration of Diabetes in Young Nod Mice with a CD4 ⁺ Islet-specific T Cell Clone

1990 • 385 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

Immunohistochemical Characterization of Monocytes-Macrophages and Dendritic Cells Involved in the Initiation of the Insulitis and β-Cell Destruction in NOD Mice

1994 • 331 citations

Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion.

1996 • 330 citations

The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus

1989 • 318 citations

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

1993 • 254 citations

Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal study.

1985 • 237 citations

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer.

1992 • 224 citations

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse.

1987 • 222 citations

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders.

1996 • 217 citations

Migration patterns of dendritic cells in the mouse. Traffic from the blood, and T cell-dependent and -independent entry to lymphoid tissues.

1988 • 215 citations

Indium-111 tropolone, a new high-affinity platelet label: preparation and evaluation of labeling parameters.

1981 • 168 citations

Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C.

1993 • 162 citations

Defective maturation and function of antigen-presenting cells in type 1 diabetes

1995 • 147 citations

Dendritic cells hold promise for immunotherapy

1997 • 135 citations

Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expression

1991 • 130 citations

Dendritic cells are the most efficient in presenting endogenous naturally processed self-epitopes to class II-restricted T cells.

1995 • 125 citations

Prevention of overt diabetes and insulitis in NOD mice by a single BCG vaccination

1990 • 124 citations

Anti‐α/β T cell receptor monoclonal antibody provides an efficient therapy for autoimmune diabetes in nonobese diabetic (NOD) mice

1991 • 89 citations

Breaking self-tolerance in nonobese diabetic mice.

1996 • 88 citations

Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?

1996 • 78 citations

Induction of autoimmunity with dendritic cells: Studies on thyroiditis in mice

1988 • 66 citations

Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element.

1987 • 63 citations

A T-cell dormant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant.

1992 • 57 citations

Paradoxical Antidiabetogenic Effect of γ-Interferon in DP-BB Rats

1998 • 38 citations

Autoimmunity to the GM2-1 Islet Ganglioside Before and at the Onset of Type I Diabetes

1996 • 28 citations

Thyroglobulin-treated blood dendritic cells induce IgG anti-thyroglobulin antibody in vitro in Hashimoto's thyroiditis

1986 • 17 citations

Insulin-dependent diabetes mellitus

1991 • 16 citations

Activated killer monocytes: preclinical model systems.

1989 • 7 citations