T Cells Can Be Activated by Peptides That Are Unrelated in Sequence to Their Selecting Peptide

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Evidence for a differential avidity model of T cell selection in the thymus

1994 • 679 citations

Depletion of CD4 ⁺ T Cells in Major Histocompatibility Complex Class II-Deficient Mice

1991 • 673 citations

Human T-cell receptor variable gene segment families

1995 • 663 citations

T-cell-receptor affinity and thymocyte positive selection

1996 • 620 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide

1994 • 497 citations

The Repertoire of T Cells Shaped by a Single MHC/Peptide Ligand

1996 • 417 citations

Structures of an MHC Class II Molecule with Covalently Bound Single Peptides

1996 • 369 citations

Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors

1991 • 366 citations

Mice Lacking H2-M Complexes, Enigmatic Elements of the MHC Class II Peptide-Loading Pathway

1996 • 337 citations

H2-M Mutant Mice Are Defective in the Peptide Loading of Class II Molecules, Antigen Presentation, and T Cell Repertoire Selection

1996 • 331 citations

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.

1993 • 326 citations

Two better cell lines for making hybridomas expressing specific T cell receptors.

1989 • 300 citations

Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

1993 • 266 citations

On the complexity of self

1991 • 261 citations

Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor

1992 • 221 citations

Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture.

1993 • 221 citations

The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules.

1994 • 196 citations

Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes.

1992 • 189 citations

A novel MHC class II epitope expressed in thymic medulla but not cortex

1989 • 175 citations

Comparison of peptides bound to spleen and thymus class II.

1993 • 168 citations

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides.

1993 • 166 citations

Mouse T-cell receptor variable gene segment families

1995 • 138 citations

Diversity of Endogenous Epitopes Bound to MHC Class II Molecules Limited by Invariant Chain

1994 • 116 citations

Positive Selection of T Cells Induced by Viral Delivery of Neopeptides to the Thymus

1997 • 108 citations

Induction of MHC-restricted specificity and tolerance in the thymus

1986 • 82 citations

The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire.

1995 • 64 citations

Cell surface expression of class II MHC proteins bound by a single peptide.

1995 • 63 citations

Permissive recognition during positive selection

1996 • 52 citations

Failure to find holes in the T-cell repertoire

1987 • 51 citations

A disease-related epitope of Torpedo acetylcholine receptor. Residues involved in I-Ab binding, self-nonself discrimination, and TCR antagonism.

1994 • 47 citations

The pigeon cytochrome c-specific T cell response of low responder mice. I. Identification of antigenic determinants on fragment 1 to 65.

1986 • 35 citations

Determination of amino acids on agretopes of pigeon cytochrome c‐related peptides specifically bound to I‐A allelic products

1994 • 29 citations