The folding mechanism of larger model proteins: role of native structure.

Principles of protein folding — A perspective from simple exact models

1995 • 1,532 citations

Protein Folding Intermediates: Native-State Hydrogen Exchange

1995 • 980 citations

How does a protein fold?

1994 • 947 citations

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

1992 • 719 citations

Knowledge-based potentials for proteins

1995 • 619 citations

Kinetics of Protein Folding

1994 • 572 citations

Engineering of stable and fast-folding sequences of model proteins.

1993 • 543 citations

Levinthal's paradox.

1992 • 495 citations

Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions

1990 • 485 citations

Specific Nucleus as the Transition State for Protein Folding: Evidence from the Lattice Model

1994 • 478 citations

Cooperativity in protein-folding kinetics.

1993 • 470 citations

Protein folding dynamics: The diffusion‐collision model and experimental data

1994 • 444 citations

Proteins with selected sequences fold into unique native conformation

1994 • 395 citations

Folding of peptide fragments comprising the complete sequence of proteins

1992 • 391 citations

Structure of proteins: packing of alpha-helices and pleated sheets.

1977 • 333 citations

De novo design of the hydrophobic cores of proteins

1995 • 301 citations

Implications of thermodynamics of protein folding for evolution of primary sequences

1990 • 279 citations

Impact of Local and Non-local Interactions on Thermodynamics and Kinetics of Protein Folding

1995 • 271 citations

Theoretical studies of protein folding and unfolding

1995 • 261 citations

Protein folding and stability: the pathway of folding of barnase

1993 • 242 citations

Molecular collapse: The rate-limiting step in two-state cytochrome c folding

1996 • 234 citations

Early steps in cytochrome c folding probed by time-resolved circular dichroism and fluorescence spectroscopy

1992 • 219 citations

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

1994 • 218 citations

Protein structure prediction by threading methods: Evaluation of current techniques

1995 • 211 citations

Is Burst Hydrophobic Collapse Necessary for Protein Folding?

1995 • 152 citations

Extracting information on folding from the amino acid sequence: Accurate predictions for protein regions with preferred conformation in the absence of tertiary interactions

1992 • 110 citations

The Refolding of Human Lysozyme: A Comparison with the Structurally Homologous Hen Lysozyme

1994 • 110 citations

A kinetic explanation for the rearrangement pathway of BPTI folding

1995 • 79 citations

Determination of the conformation of folding initiation sites in proteins by computer simulation

1995 • 46 citations

How are close residues of protein structures distributed in primary sequence?

1995 • 31 citations