Folding of peptide fragments comprising the complete sequence of proteins

Investigation of exchange processes by two-dimensional NMR spectroscopy

1979 • 4,720 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins^*

1967 • 3,423 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

1983 • 2,327 citations

Structure determination of a tetrasaccharide: transient nuclear Overhauser effects in the rotating frame

1984 • 1,650 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

The Solubility of Amino Acids and Two Glycine Peptides in Aqueous Ethanol and Dioxane Solutions

1971 • 1,417 citations

INTERMEDIATES IN THE FOLDING REACTIONS OF SMALL PROTEINS

1990 • 1,133 citations

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

1975 • 1,108 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR

1988 • 823 citations

Polypeptide secondary structure determination by nuclear magnetic resonance observation of short proton-proton distances

1984 • 756 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Folding and association of proteins

1987 • 697 citations

Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra

1982 • 585 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

[27] Circular dichroism and optical rotatory dispersion of proteins and polypeptides

1973 • 547 citations

Experimental studies of protein folding and unfolding

1979 • 535 citations

Characterization of a Helical Protein Designed from First Principles

1988 • 533 citations

Defining Solution Conformations of Small Linear Peptides

1991 • 528 citations

Calibration of the methanol and glycol nuclear magnetic resonance thermometers with a static thermistor probe

1968 • 519 citations

Occurrence and role ofcis peptide bonds in protein structures

1990 • 516 citations

Structure of oxidized poplar plastocyanin at 1·6 Å resolution

1983 • 508 citations

Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding

1988 • 463 citations

Transient folding intermediates characterized by protein engineering

1990 • 446 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 437 citations

Protein folding: local structures, domains, subunits, and assemblies

1991 • 432 citations

Structure of myohemerythrin in the azidomet state at resolution

1987 • 377 citations

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

1990 • 372 citations

Obtaining high-fidelity powder spectra in anisotropic media: Phase-cycled Hahn echo spectroscopy

1983 • 358 citations

Structural principles of the globular organization of protein chains. A stereochemical theory of globular protein secondary structure

1974 • 355 citations

Crystal Structures of an Antibody to a Peptide and Its Complex with Peptide Antigen at 2.8 Å

1990 • 352 citations

Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance

1983 • 336 citations

Improved techniques for homonuclear rotating-frame and isotropic mixing experiments

1987 • 335 citations

Simulations of the Folding of a Globular Protein

1990 • 322 citations

Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

1986 • 321 citations

Nature of the charged-group effect on the stability of the C-peptide helix.

1985 • 313 citations

Helix-coil transition of the isolated amino terminus of ribonuclease

1971 • 310 citations

Folding of Polypeptide Chains in Proteins: A Proposed Mechanism for Folding

1971 • 309 citations

Circular dichroism studies of distorted α-helices, twisted β-sheets, and β-turns

1988 • 282 citations

The X‐Pro peptide bond as an nmr probe for conformational studies of flexible linear peptides

1976 • 270 citations

Demonstration by NMR of folding domains in lysozyme

1991 • 246 citations

The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn

1985 • 225 citations

Molecular dynamics simulations of the unfolding of an .alpha.-helical analog of ribonuclease A S-peptide in water

1991 • 217 citations

Detection and characterization of a folding intermediate in barnase by NMR

1990 • 212 citations

Persistence of the .alpha.-helix stop signal in the S-peptide in trifluoroethanol solutions

1989 • 212 citations

Water-Inserted α-Helical Segments Implicate Reverse Turns as Folding Intermediates

1989 • 210 citations

A helix stop signal in the isolated S-peptide of ribonuclease A

1984 • 189 citations

Optical activity of polypeptides and proteins

1972 • 188 citations

Circular Dichroism and Its Empirical Application to Biopolymers

1985 • 186 citations

Diffusion–collision model for protein folding

1979 • 183 citations

Early folding intermediate of ribonuclease A.

1990 • 180 citations

Dynamic Monte Carlo simulations of a new lattice model of globular protein folding, structure and dynamics

1991 • 170 citations

The influence of long-range interactions on the structure of myoglobin

1968 • 169 citations

Tilden Lecture. Structure and electron-transfer reactivity of the blue copper protein plastocyanin

1985 • 168 citations

Folding of peptide fragments comprising the complete sequence of proteins

1992 • 168 citations

Theoretical study of the contribution of aromatic side chains to the circular dichroism of basic bovine pancreatic trypsin inhibitor

1989 • 168 citations

SENSITIVE CRITERIA FOR THE CRITICAL SIZE FOR HELIX FORMATION IN OLIGOPEPTIDES

1969 • 163 citations

An Experimental Approach to the Study of the Folding of Staphylococcal Nuclease

1969 • 156 citations

Thermodynamics and mechanism of .alpha. helix initiation in alanine and valine peptides

1991 • 154 citations

Proton NMR studies of the solution conformations of an analog of the C-peptide of ribonuclease A

1989 • 154 citations

Protein-solvent interactions and protein conformation

1970 • 146 citations

Local structures in unfolded lysozyme and correlation with secondary structures in the native conformation: Helix‐forming or ‐breaking propensity of peptide segments

1991 • 139 citations

Solution conformational preferences of immunogenic peptides derived from the principal neutralizing determinant of the HIV-1 envelope glycoprotein gp120

1991 • 138 citations

Unfolding of an α‐helix in water

1991 • 134 citations

Hydrophobic clustering in nonnative states of a protein: Interpretation of chemical shifts in NMR spectra of denatured states of lysozyme

1991 • 132 citations

The Physical Basis for Induction of Protein-Reactive Antipeptide Antibodies

1988 • 130 citations

Crystal structure of plastocyanin from a green alga, Enteromorpha prolifera

1990 • 126 citations

High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin

1991 • 108 citations

Mechanisms of protein and polypeptide helix initiation

1975 • 107 citations

How does protein synthesis give rise to the 3D‐structure?

1991 • 107 citations

Local interactions in bends of proteins.

1977 • 104 citations

Formation of local structures in protein folding

1989 • 102 citations

Design and characterization of peptides with amphiphilic β‐strand structures

1985 • 98 citations

The dynamics of the helix‐coil transition in poly‐α, <scp>L</scp>‐glutamic acid

1964 • 97 citations

Computer Simulations of Globular Protein Folding and Tertiary Structure

1989 • 97 citations

Nanosecond timescale folding dynamics of a pentapeptide in water

1991 • 95 citations

Conformational preferences of synthetic peptides derived from the immunodominant site of the circumsporozoite protein of Plasmodium falciparum by proton NMR

1990 • 89 citations

Three-Dimensional Solution Structure of Plastocyanin from the Green Alga Scenedesmus obliquus

1988 • 87 citations

Structure of the binuclear iron complex in metazidohaemerythrin from Themiste dyscritum at 2.2. Å resolution

1981 • 86 citations

Secondary structure of the Arg‐Gly‐Asp recognition site in proteins involved in cell‐surface adhesion

1988 • 83 citations

Current Research in Protein Chemistry

1990 • 83 citations

The second translation of the genetic message: protein folding and assembly

1985 • 77 citations

Conformational analysis of COOH-terminal segments of human C3a. Evidence of ordered conformation in an active 21-residue peptide.

1984 • 77 citations

Comparison of lattice Monte Carlo dynamics and Brownian dynamics folding pathways of α-helical hairpins

1991 • 76 citations

Surface amino acids as sites of temperature-sensitive folding mutations in the P22 tailspike protein.

1988 • 74 citations

Complete assignment of the 1H nuclear magnetic resonance spectrum of French bean plastocyanin

1988 • 67 citations

Beta poly(l-lysine): A model system for biological self-assembly

1974 • 56 citations

¹H‐NMR assignment and secondary structure of a Herpes simplex virus glycoprotein D‐1 antigenic domain

1986 • 55 citations

Characterisation of a Local Structure in the Synthetic Parathyroid Hormone Fragment 1-34 by 1H Nuclear-Magnetic-Resonance Techniques

1978 • 54 citations

Dynamic Monte Carlo simulations of globular protein folding/unfolding pathways

1990 • 54 citations

Mapping the anatomy of the immunodominant domain of the human immunodeficiency virus gp41 transmembrane protein: peptide conformation analysis using monoclonal antibodies and proton nuclear magnetic resonance spectroscopy

1991 • 52 citations

Folding of a peptide corresponding to the .alpha.-helix in bovine pancreatic trypsin inhibitor

1989 • 52 citations

Conformation of a T cell stimulating peptide in aqueous solution

1989 • 50 citations

Structural studies with the uveopathogenic peptide M derived from retinal S-antigen

1990 • 48 citations

The primary structure of myohemerythrin

1976 • 47 citations

Theoretical evidence for destabilization of an .alpha.-helix by water insertion: molecular dynamics of hydrated decaalanine

1990 • 44 citations

The C-peptide Helix from Ribonuclease A Considered as an Autonomous Folding Unit

1987 • 44 citations

Helix–coil transition kinetics in aqueous poly(α,<scp>L</scp>‐glutamic acid)

1975 • 41 citations

Relative effects of primary and tertiary structure on helix formation in myoglobin and α-lactalbumin

1971 • 41 citations

Tendamistat (12–26) fragment

1991 • 35 citations

The amino acid sequence of plastocyanin from French bean (Phaseolus vulgaris)

1974 • 33 citations

Location of an .alpha.-helix in fragment 96-133 from bovine somatotropin by proton NMR spectroscopy

1988 • 32 citations

Dynamic monte carlo simulations of globular protein folding

1990 • 28 citations

Detection of the helix-coil transition of polypeptides by ultrasonic absorption measurements in the megahertz range. Case of poly-L-glutamic acid

1972 • 24 citations

Reduced tendency to form a .beta. turn in peptides from the P22 tailspike protein correlates with a temperature-sensitive folding defect

1990 • 23 citations

Synthesis and physicochemical characterization of major fragments of human leukocyte interferon .alpha.1

1984 • 16 citations

T-cell antigenic peptides from sperm whale myoglobin fold as amphipathic helices: a possible determinant for immunodominance?

1989 • 14 citations

Immunogenic peptides corresponding to the dominant antigenic region alanine-597 to cysteine-619 in the transmembrane protein of simian immunodeficiency virus have a propensity to fold in aqueous solution

1992 • 13 citations

Synthesis and solubility properties of peptide fragments of human hemoglobin α‐chain (123‐136)

1988 • 10 citations

THE H-HELIX OF MYOGLOBIN AS A POTENTIAL INDEPENDENT PROTEIN FOLDING DOMAIN

1990 • 8 citations

Advances in protein design international workshop 1988

1990 • 7 citations

Tests Of Isolated β–Sheet Formation In A Cyclic Peptide From BPTI

1990 • 3 citations

Sensitive Criteria For the Critical Size For Helix Formation in Oligopeptides

1970 • 1 citations

Deleted Work

1955 • 0 citations