The role of hinge domain in heterodimerization and specific DNA recognition by nuclear receptors

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Role of CBP/P300 in nuclear receptor signalling

1996 • 935 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Zinc fingers: Gilt by association

1988 • 799 citations

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

1988 • 705 citations

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

1996 • 702 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

Structural determinants of nuclear receptor assembly on DNA direct repeats

1995 • 561 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

MINIREVIEW: The Steroid Receptor Superfamily: More Excitement Predicted for the Future

1990 • 489 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Identification of a Novel Thyroid Hormone Receptor Expressed in the Mammalian Central Nervous System

1987 • 429 citations

Thyroid hormone receptor α isoforms generated by alternative splicing differentially activate myosin HC gene transcription

1988 • 425 citations

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

1996 • 410 citations

A novel protein complex that interacts with the vitamin D₃ receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

1998 • 391 citations

Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).

1992 • 354 citations

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

1987 • 347 citations

A Domain Containing Leucine-Zipper-Like Motifs Mediate Novelin VivoInteractions between the Thyroid Hormone and Retinoic Acid Receptors

1989 • 293 citations

Identification of a Rat c-erbAα-Related Protein Which Binds Deoxyribonucleic Acid but does not Bind Thyroid Hormone

1988 • 254 citations

Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.

1988 • 237 citations

RIP-140 Interacts with Multiple Nuclear Receptors by Means of Two Distinct Sites

1996 • 132 citations

Defining a minimal estrogen receptor DNA binding domain

1993 • 124 citations

Resistance to Thyroid Hormone Caused by Two Mutant Thyroid Hormone Receptors β, R243Q and R243W, with Marked Impairment of Function That Cannot Be Explained by Alteredin Vitro3,5,3′-Triiodothyroinine Binding Affinity¹

1997 • 106 citations

Inhibition of Nuclear Receptor Signalling by Poly(ADP-Ribose) Polymerase

1999 • 95 citations

A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes.

1987 • 87 citations

Characterization of Site-Specific Polyclonal Antibodies to c-erbA Peptides Recognizing Human Thyroid Hormone Receptors α1, α2, and β and native 3,5,3′- Triiodothyronine Receptor, and Study of Tissue Distribution of the Antigen

1990 • 74 citations

Ligand-binding and heterodimerization activities of a conserved region in the ligand-binding domain of the thyroid hormone receptor.

1991 • 54 citations

A point mutation (Ala229 to Thr) in the hinge domain of the c-erbA beta thyroid hormone receptor gene in a family with generalized thyroid hormone resistance.

1992 • 52 citations

The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.

1990 • 50 citations

An Essential Role of Domain D in the Hormone-Binding Activity of Human β1 Thyroid Hormone Nuclear Receptor

1991 • 49 citations

The avian erythroblastosis virus erbA oncogene encodes a DNA-binding protein exhibiting distinct nuclear and cytoplasmic subcellular localizations

1988 • 47 citations

Functional Interaction between Oct-1 and Retinoid X Receptor

1999 • 42 citations

Ligand-dependent Heterodimerization of Thyroid Hormone Receptor and Retinoid X Receptor

1997 • 35 citations

The Differential Hormone-dependent Transcriptional Activation of Thyroid Hormone Receptor Isoforms Is Mediated by Interplay of Their Domains

1997 • 34 citations

Purification and characterization of rat liver nuclear thyroid hormone receptors.

1987 • 34 citations

A Novel Multifunctional Motif in the Amino-terminal A/B Domain of T3Rα Modulates DNA Binding and Receptor Dimerization

1998 • 26 citations

A Zebrafish Ftz-F1 (Fushi Tarazu Factor 1) Homologue Requires Multiple Subdomains in the D and E Regions for Its Transcriptional Activity

2000 • 18 citations

Structure of the hormone binding domain of human .beta.1 thyroid hormone nuclear receptor: Is it an .alpha./.beta. barrel?

1993 • 16 citations