Ligand-binding and heterodimerization activities of a conserved region in the ligand-binding domain of the thyroid hormone receptor.

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome

1988 • 1,007 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Evidence That the Leucine Zipper Is a Coiled Coil

1989 • 869 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

1989 • 614 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

COUP transcription factor is a member of the steroid receptor superfamily

1989 • 480 citations

Identification of a Novel Thyroid Hormone Receptor Expressed in the Mammalian Central Nervous System

1987 • 429 citations

MINIREVIEW: Interactions Among a Subfamily of Nuclear Hormone Receptors: The Regulatory Zipper Model

1990 • 428 citations

Contrasting developmental and tissue-specific expression of alpha and beta thyroid hormone receptor genes.

1990 • 308 citations

A Domain Containing Leucine-Zipper-Like Motifs Mediate Novelin VivoInteractions between the Thyroid Hormone and Retinoic Acid Receptors

1989 • 293 citations

Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.

1989 • 261 citations

Identification of a Rat c-erbAα-Related Protein Which Binds Deoxyribonucleic Acid but does not Bind Thyroid Hormone

1988 • 254 citations

Xenopus laevis alpha and beta thyroid hormone receptors.

1990 • 244 citations

Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.

1988 • 237 citations

Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor.

1988 • 225 citations

Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element

1989 • 219 citations

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

1990 • 192 citations

3,5,3′-Triiodothyronine (T₃) Receptor-Auxiliary Protein (TRAP) Binds DNA and Forms Heterodimers with the T₃Receptor

1991 • 130 citations

Characterization of a Third Human Thyroid Hormone Receptor Coexpressed with Other Thyroid Hormone Receptors in Several Tissues

1988 • 110 citations

Thyroid Hormone Receptor Mutations that Interfere with Transcriptional Activation also Interfere with Receptor Interaction with a Nuclear Protein

1991 • 93 citations

A 22-amino-acid peptide restores DNA-binding activity to dimerization-defective mutants of the estrogen receptor.

1990 • 89 citations

Thyroid Hormone Receptors Form Distinct Nuclear Protein-Dependent and Independent Complexes with a Thyroid Hormone Response Element

1990 • 82 citations

3,5,3′-Triiodothyronine Receptor Auxiliary Protein (TRAP) Enhances Receptor Binding by Interactions within the Thyroid Hormone Response Element

1991 • 73 citations

The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.

1990 • 50 citations