Endocrine effects of IGF-I on normal and transformed breast epithelial cells: potential relevance to strategies for breast cancer treatment and prevention

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

1995 • 4,419 citations

Nutritional Regulation of the Insulin-Like Growth Factors*

1994 • 1,537 citations

Intrauterine Growth Retardation and Postnatal Growth Failure Associated with Deletion of the Insulin-Like Growth Factor I Gene

1996 • 1,094 citations

Cell Proliferation in Carcinogenesis

1990 • 1,063 citations

Octreotide

1996 • 956 citations

Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index

1994 • 696 citations

Insulin-like growth factor binding proteins and their role in controlling IGF actions

1997 • 510 citations

Diet, Body Size, and Breast Cancer

1993 • 497 citations

Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.

1985 • 495 citations

Genetic errors, cell proliferation, and carcinogenesis.

1991 • 477 citations

Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation.

1995 • 439 citations

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

1993 • 399 citations

Birthweight as a risk factor for breast cancer

1996 • 376 citations

Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice.

1989 • 334 citations

Endocrine Control of Mammary-Gland Development and Function in the C3H/He Crgl Mouse<xref ref-type="fn" rid="FN1">2</xref>

1958 • 281 citations

Sequence-Function Relationships Within the Expanding Family of Prolactin, Growth Hormone, Placental Lactogen, and Related Proteins in Mammals*

1996 • 280 citations

Height and weight in relation to breast cancer morbidity and mortality. A prospective study of 570,000 women in Norway

1989 • 280 citations

Plasma insulin-like growth factor-1 (IGF-1) concentrations in human breast cancer

1993 • 276 citations

Effect of Tamoxifen on Serum Insulinlike Growth Factor I Levels in Stage I Breast Cancer Patients

1990 • 264 citations

Risk of breast cancer associated with atypical hyperplasia of lobular and ductal types.

1997 • 246 citations

Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor.

1989 • 233 citations

Estradiol and Antiestrogens Regulate a Growth Inhibitory Insulin-like Growth Factor Binding Protein 3 Autocrine Loop in Human Breast Cancer Cells

1996 • 225 citations

Total calories, body weight, and tumor incidence in mice.

1987 • 222 citations

Insulin‐like growth‐factor‐binding protein 3 is decreased in early‐stage operable pre‐menopausal breast cancer

1995 • 219 citations

Receptors for epidermal growth factor and insulin-like growth factor I and their relation to steroid receptors in human breast cancer.

1988 • 208 citations

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

1995 • 190 citations

Adjuvant Therapy of Cancer

1978 • 173 citations

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression.

1996 • 164 citations

Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation.

1996 • 160 citations

In vitro and in vivo studies of antagonistic effects of human growth hormone analogs.

1994 • 143 citations

Receptor-Associated Resistance to Growth Hormone-Releasing Factor in Dwarf "Little" Mice

1986 • 133 citations

Breast cancer incidence according to weight and height in two cities of the Netherlands and in Aichi prefecture, Japan

1977 • 129 citations

In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen.

1993 • 123 citations

Intact and amino-terminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development.

1992 • 114 citations

Regulation of Insulin-Like Growth Factor-Binding Protein (IGFBP) Expression by Breast Cancer Cells: Use of IGFBP-1 as as Inhibitor of Insulin-like Growth Factor Action

1992 • 107 citations

NON-LACTOGENIC EFFECTS OF GROWTH HORMONE ON GROWTH AND INSULIN-LIKE GROWTH FACTOR-I MESSENGER RIBONUCLEIC ACID OF RAT MAMMARY GLAND

1990 • 105 citations

Influence of tamoxifen on plasma levels of insulin-like growth factor I and insulin-like growth factor binding protein I in breast cancer patients.

1992 • 103 citations

Synthesis and biological activities of highly potent antagonists of growth hormone-releasing hormone.

1994 • 97 citations

Body height and risk of breast cancer. A prospective study of 23,831 Norwegian women

1990 • 92 citations

Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas.

1994 • 85 citations

Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780.

1996 • 83 citations

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice

1992 • 82 citations

Mechanism of Action of Prolactin in the Control of Mammary Gland Function

1980 • 76 citations

Characterization of insulin-like growth factor I (IGF-I) receptors of human breast cancer cells

1988 • 76 citations

Insulin-like growth factors (IGFs) and IGF binding proteins-1, -2, and -3 in newborn serum: relationships to fetoplacental growth at term

1996 • 75 citations

The insulin-like growth factor system as a target in breast cancer

1994 • 68 citations

A role for insulin-like growth factor binding protein 5 in the antiproliferative action of the antiestrogen ICI 182780.

1996 • 66 citations

Tamoxifen attenuates pulsatile growth hormone secretion: mediation in part by somatostatin.

1992 • 65 citations

Adjuvant therapy of cancer VII

1994 • 63 citations

Prolactin and Growth Hormone Levels in Different Inbred Strains of Mice: Patterns in Association with Estrous Cycle, Time of Day, and Perphenazine Stimulation

1975 • 62 citations

Induction of mammary adenocarcinomas in metallothionein promoter‐human growth hormone transgenic mice

1991 • 56 citations

Enhancement of Tamoxifen-Induced Suppression of Insulin-Like Growth Factor I Gene Expression and Serum Level by a Somatostatin Analogue

1994 • 54 citations

The effect of endocrine therapy with medroxyprogesterone acetate, 4‐hydroxyandrostenedione or tamoxifen on plasma concentrations of insulin‐like growth factor (IGF)‐I, IGF‐II and IGFBP‐1 in women with advanced breast cancer

1992 • 52 citations

Suppression of serum insulin-like growth factor-1 levels in breast cancer patients during adjuvant tamoxifen therapy

1993 • 51 citations

Influence of tamoxifen, aminoglutethimide and goserelin on human plasma IGF-I levels in breast cancer patients

1992 • 48 citations

Direct effects of tamoxifen on growth hormone secretion by pituitary cells in vitro

1992 • 45 citations

Hypophysectomy in Treatment of Disseminated Breast Cancer

1962 • 39 citations

Growth factor binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors from rats subject to chronic caloric restriction.

1989 • 37 citations

Antiestrogen treatment of breast cancer: an overview.

1982 • 37 citations

Reproductive performance and fetal growth in female mice from lines divergently selected on the basis of plasma IGF-1 concentrations

1989 • 36 citations

Co-Expression of Bovine Growth Hormone (GH) and Human GH Antagonist Genes in Transgenic Mice

1997 • 28 citations

Serum, pituitary and urine concentrations of prolactin and growth hormone in eight strains of mice with varying incidence of mammary tumors

1979 • 26 citations

Effects of Hypophysectomy in Man

1956 • 26 citations

Incidence and mortality of breast cancer related to body height and living conditions during childhood and adolescence

1992 • 24 citations

Breast carcinoma and skeletal formation

1992 • 14 citations

Epidemiology of familial predisposition for breast cancer in Japan.

1982 • 11 citations

Endocrine Management of Metastatic Breast Cancer

1956 • 6 citations

Deleted Work

1955 • 0 citations