Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice.

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

Estrogenic Regulation of Growth and Polypeptide Growth Factor Secretion in Human Breast Carcinoma

1987 • 576 citations

Growth Inhibition of Human Tumor Cells in Athymic Mice by Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies

1984 • 443 citations

Expression of Transforming Growth Factor α and its Messenger Ribonucleic Acid in Human Breast Cancer: Its Regulation by Estrogen and its Possible Functional Significance

1988 • 440 citations

Monoclonal antibodies to receptors for insulin and somatomedin-C.

1983 • 423 citations

Expression and characterization of a functional human insulin-like growth factor I receptor.

1988 • 313 citations

Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells.

1986 • 310 citations

Estrogen-Induced Factors of Breast Cancer Cells Partially Replace Estrogen to Promote Tumor Growth

1986 • 273 citations

Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts.

1986 • 269 citations

Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture.

1984 • 256 citations

Transforming growth factor beta: potential autocrine growth inhibitor of estrogen receptor-negative human breast cancer cells.

1988 • 247 citations

Hormone responsive human breast cancer in long-term tissue culture: effect of insulin.

1976 • 222 citations

Receptors for epidermal growth factor and insulin-like growth factor I and their relation to steroid receptors in human breast cancer.

1988 • 208 citations

The Type II Insulin-Like Growth Factor (IGF) Receptor Has Low Affinity for IGF-I Analogs: Pleiotypic Actions of IGFs on Myoblasts Are Apparently Mediated by the Type I Receptor*

1987 • 204 citations

Multihormonal Regulation of Insulin-Like Growth Factor-I-Related Protein in MCF-7 Human Breast Cancer Cells

1988 • 161 citations

Evidence from Monoclonal Antibody Studies that Insulin Stimulates Deoxyribonucleic Acid Synthesis through the Type I Somatomedin Receptor*

1985 • 160 citations

An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture

1987 • 155 citations

Receptor binding and growth-promoting activity of insulin-like growth factors in human breast cancer cells (T-47D) in culture.

1984 • 139 citations

Insulin-like Growth Factors in Pygmies

1987 • 112 citations

The Type II Insulin-Like Growth Factor Receptor Does Not Mediate Deoxyribonucleic Acid Synthesis in Human Fibroblasts*

1987 • 108 citations

The type I insulin-like growth factor receptor mediates the rapid effects of multiplication-stimulating activity on membrane transport systems in rat soleus muscle.

1984 • 104 citations

Interaction of the Monoclonal AntibodiesαlR-1 andαIR-3 with Insulin and Somatomedin-C Receptors

1986 • 78 citations

Expression and characterization of a functional human insulin like growth factor-I receptor. J Biol Chem 263:11486-11492

1988 • 57 citations

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1986 • 45 citations

Perturbation by insulin of human breast cancer cell cycle kinetics.

1984 • 44 citations

Partial characterization of somatomedin C-like immunoreactivity secreted by breast cancer cells in vitro

1987 • 41 citations

The Human Erythrocyte Insulin-Like Growth Factor I Receptor:Characterization and Demonstration of Ligand-Stimulated Autophosphorylation

1986 • 34 citations