Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's disease

A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease

1997 • 3,152 citations

Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.

1976 • 3,140 citations

Development of a Crohn's Disease Activity Index

1976 • 3,024 citations

Treatment of Crohn's Disease with 6-Mercaptopurine

1980 • 1,055 citations

Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human Monocytes

1995 • 698 citations

Vascular Complications of Inflammatory Bowel Disease

1986 • 649 citations

Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group

1997 • 493 citations

Interleukin-11: Review of Molecular, Cell Biology, and Clinical Use

1997 • 386 citations

Immunosuppressive and Anti-inflammatory Properties of Interleukin 10

1995 • 385 citations

A randomized placebo-controlled trial of recombinant human interleukin-11 in cancer patients with severe thrombocytopenia due to chemotherapy

1996 • 299 citations

Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production.

1996 • 290 citations

A phase I trial of recombinant human interleukin-11 (neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy

1996 • 216 citations

IL-11 regulates macrophage effector function through the inhibition of nuclear factor-kappaB.

1997 • 198 citations

Interleukin-11 prevents apoptosis and accelerates recovery of small intestinal mucosa in mice treated with combined chemotherapy and radiation.

1996 • 186 citations

Recombinant human interleukin-11 stimulates megakaryocytopoiesis and increases peripheral platelets in normal and splenectomized mice

1993 • 162 citations

A bone marrow stromal-derived growth factor, interleukin-11, stimulates recovery of small intestinal mucosal cells after cytoablative therapy

1994 • 161 citations

Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin.

1997 • 152 citations

IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology.

1994 • 127 citations

Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats

1996 • 118 citations

Protection of the Small Intestinal Clonogenic Stem Cells from Radiation‐Induced Damage by Pretreatment with Interleukin 11 also Increases Murine Survival Time

1996 • 94 citations

Recombinant human interleukin-11 stimulates multilineage hematopoietic recovery in mice after a myelosuppressive regimen of sublethal irradiation and carboplatin

1994 • 93 citations

Recombinant human interleukin-11 stimulates multilineage hematopoietic recovery in mice after a myelosuppressive regimen of sublethal irradiation and carboplatin

1994 • 75 citations

Alteration in the frequency, severity and duration of chemotherapy-induced mucositis in hamsters by interleukin-11

1995 • 69 citations

MITIGATING EFFECTS OF INTERLEUKIN 11 ON CONSECUTIVE COURSES OF 5-FLUOROURACIL-INDUCED ULCERATIVE MUCOSITIS IN HAMSTERS

1997 • 67 citations

Administration of interleukin‐10 abolishes innate resistance to Listeria monocytogenes

1996 • 63 citations

Interleukin-11 induces intestinal epithelial cell growth arrest through effects on retinoblastoma protein phosphorylation.

1996 • 54 citations

The biology of interleukin 11

1996 • 46 citations

Effects of IL‐11 on the growth of intestinal epithelial cells in vitro

1995 • 46 citations

Advances in the Assessment of Disease Activity in Inflammatory Bowel Disease

1989 • 34 citations

Recombinant Human Interleukin‐11 Has Anti‐inflammatory Actions Yet Does Not Exacerbate SystemicListeriaInfection

2000 • 17 citations

Hemostatic tests in the prediction of atherothrombotic disease

1997 • 15 citations

Recombinant human interleukin-11 (rhlL-11) decreases inflammatory bowel disease in HLA-B27 transgenic rats

1995 • 6 citations

Dose response and schedule studies of recombinant human interleukin-11 in acetic acid-induced colonic injury in rats

1995 • 5 citations

Deleted Work

1955 • 0 citations