The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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DNA sequencing with chain-terminating inhibitors

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

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1983 • 26,063 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

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ABC Transporters: From Microorganisms to Man

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1981 • 3,715 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

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Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

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Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

1993 • 1,175 citations

A conserved tripeptide sorts proteins to peroxisomes.

1989 • 1,113 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

BIOCHEMISTRY OF PEROXISOMES

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Spliced early mRNAs of simian virus 40

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A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria

1986 • 753 citations

[40] Immunofluorescence methods for yeast

1991 • 705 citations

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1984 • 668 citations

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1989 • 604 citations

Phosphatidylcholine translocase: A physiological role for the mdr2 gene

1994 • 600 citations

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

1989 • 443 citations

A molecular model of MHC class-I-restricted antigen processing

1992 • 438 citations

Protein Import into Peroxisomes and Biogenesis of the Organelle

1993 • 411 citations

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

1992 • 407 citations

Isolation of the yeast calmodulin gene: Calmodulin is an essential protein

1986 • 400 citations

[39] Unified approach to alignment and phylogenies

1990 • 398 citations

The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily.

1990 • 395 citations

The functions and consensus motifs of nine types of peptide segments that form different types of nucleotide‐binding sites

1994 • 388 citations

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1990 • 376 citations

Porins and specific channels of bacterial outer membranes

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Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae.

1989 • 326 citations

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1992 • 322 citations

Proliferation of microbodies in Saccharomyces cerevisiae

1987 • 302 citations

Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome

1992 • 228 citations

Yeast promoters: Positive and negative elements

1984 • 227 citations

Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy.

1988 • 219 citations

Functional Complementation of Yeast ste6 by a Mammalian Multidrug Resistance mdr Gene

1992 • 218 citations

PAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane protein essential for peroxisome biogenesis.

1991 • 218 citations

An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast.

1995 • 200 citations

Acyl-CoA oxidase contains two targeting sequences each of which can mediate protein import into peroxisomes.

1988 • 196 citations

Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product.

1992 • 195 citations

Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae.

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Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast.

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1990 • 136 citations

PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene.

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Traffic ATPases: A Superfamily of Transport Proteins Operating from Escherichia coli to Humans

1992 • 129 citations

Isolation of peroxisome assembly mutants from Saccharomyces cerevisiae with different morphologies using a novel positive selection procedure.

1992 • 123 citations

Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria.

1984 • 102 citations

Structure and transcriptional control of the Saccharomyces cerevisiae POX1 gene encoding acylcoenzyme A oxidase

1990 • 102 citations

Peroxisomal biogenesis: multiple pathways of protein import.

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Induction of the yeast α-specific STE3 gene by the peptide pheromone a-factor

1984 • 97 citations

An efficient positive selection procedure for the isolation of peroxisomal import and peroxisome assembly mutants of Saccharomyces cerevisiae.

1993 • 92 citations

Secretion of Peptides and Proteins Lacking Hydrophobic Signal Sequences: The Role of Adenosine Triphosphate-Driven Membrane Translocators*

1992 • 92 citations

Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae.

1992 • 83 citations

A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus.

1994 • 78 citations

The peroxisomal targeting signal of 3‐oxoacyl‐coA thiolase from Saccharomyces cerevisiae

1994 • 70 citations

<scp>XII</scp><scp>XVI</scp>. Yeast sequencing reports. Mapping and sequencing of two yeast genes belonging to the ATP‐binding cassette superfamily

1994 • 69 citations

Peroxisomes in Saccharomyces cerevisiae: immunofluorescence analysis and import of catalase A into isolated peroxisomes.

1991 • 69 citations

Novel peroxisome clustering mutants and peroxisome biogenesis mutants of Saccharomyces cerevisiae.

1993 • 58 citations

Biophysical studies of signal peptides: Implications for signal sequence functions and the involvement of lipid in protein export

1990 • 54 citations

Genetic and Biochemical Characterization of a Phosphatidylinositol-Specific Phospholipase C in Saccharomyces cerevisiae

1993 • 49 citations

A new glucose‐repressible gene identified from the analysis of chromatin structure in deletion mutants of yeast SUC2 locus

1991 • 46 citations

<scp>XI</scp>. Yeast sequencing reports. The yeast YKL741 gene situated on the left arm of chromosome XI codes for a homologue of the human ALD protein

1994 • 41 citations

Genetic approaches to studying peroxisome biogenesis

1993 • 38 citations

Peroxisomal disorders

1991 • 33 citations

Dedicated Transporters for Peptide Export and Intercompartmental Traffic in the Yeast Saccharomyces cerevisiae

1992 • 22 citations

Peroxisomes in Saccharomyces cerevisiae: Immunofluorescence Analysis and Import of Catalase A into Isolated Peroxisomes

1991 • 20 citations

Peroxisome biogenesis in yeast

1992 • 17 citations