Increased interleukin-1 production by peripheral blood mononuclear cells in patients with multiple sclerosis

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS

1965 • 1,402 citations

There is more than one interleukin 1

1986 • 1,226 citations

Loss of Suppressor T Cells in Active Multiple Sclerosis

1980 • 446 citations

Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes.

1987 • 426 citations

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.

1987 • 418 citations

Two distinct factors are required for induction of T-cell growth

1980 • 416 citations

Criteria for the clinical diagnosis of multiple sclerosis

1976 • 376 citations

Interleukin 2: the molecule and its function

1984 • 367 citations

Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain.

1986 • 316 citations

Multiple sclerosis: Capping of surface immunoglobulin G on macrophages engaged in myelin breakdown

1981 • 259 citations

On cerebrospinal fluid immunoglobulin-G (IgG) quotients in multiple sclerosis and other diseases

1970 • 246 citations

Hypothesis: A role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis

1988 • 199 citations

Detection of in Vivo Stimulated Cerebrospinal-Fluid Lymphocytes by Flow Cytometry in Patients with Multiple Sclerosis

1980 • 111 citations

In vitro study of mediators of inflammation in multiple sclerosis

1989 • 91 citations

Demyelinating diseases. Basic and clinical electrophysiology.

1981 • 63 citations

Interleukin‐2 levels in serum and cerebrospinal fluid of multiple sclerosis patients

1988 • 60 citations

Anti-endothelial cell antibodies and circulating immune complexes in the sera of patients with multiple sclerosis

1987 • 56 citations

Is prostaglandin E2 involved in the pathogenesis of fever? Effects of interleukin-1 on the release of prostaglandins.

1986 • 56 citations

Elevated Levels of Soluble Interleukin-2 Receptors in Multiple Sclerosis

1988 • 56 citations

Activated T lymphocytes in patients with multiple sclerosis

1983 • 51 citations

Lymphokines and the brain

1984 • 31 citations

Interleukin-1 and interleukin-2 production by peripheral blood mononuclear cells in multiple sclerosis patients

1988 • 28 citations

The enigma of oligoclonal immunoglobulin G in cerebrospinal fluid from multiple sclerosis patients

1981 • 26 citations

Multiple sclerosis: effect of myelin basic protein on interleukin 1, interleukin 2 production and interleukin 2 receptor expression in vitro.

1988 • 23 citations

Autoantibodies to each protein fraction extracted from cerebral endothelial cell membrane in the sera of patients with multiple sclerosis

1989 • 20 citations