Lymphokines and the brain

Towards a network theory of the immune system.

1974 • 3,379 citations

Interleukin-1

1984 • 1,625 citations

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Sleep-promoting effects of endogenous pyrogen (interleukin-1)

1984 • 450 citations

The Immune Response Evokes Changes in Brain Noradrenergic Neurons

1983 • 442 citations

Epidermal cell (keratinocyte)-derived thymocyte-activating factor (ETAF).

1981 • 420 citations

Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects.

1984 • 367 citations

Short Papers

1977 • 360 citations

Changes in Blood Hormone Levels during the Immune Response

1975 • 342 citations

Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages.

1980 • 260 citations

Interleukin 1 is more than an interleukin

1982 • 257 citations

Molecular basis of fever in humans

1982 • 252 citations

The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen

1981 • 224 citations

Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation

1981 • 217 citations

What do the immune system and the brain know about each other?

1983 • 191 citations

Lymphokine-containing supernatants from con A-stimulated cells increase corticosterone blood levels.

1981 • 189 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen.

1979 • 182 citations

Synthesis by a clonal line of rat glial cells of a protein unique to the nervous system

1970 • 178 citations

Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis

1974 • 158 citations

Specific adoptive therapy of established leukemia with syngeneic lymphocytes sequentially immunized in vivo and in vitro and nonspecifically expanded by culture with Interleukin 2.

1981 • 130 citations

Prostaglandin E levels in third ventricular cerebrospinal fluid of rabbits during fever and changes in body temperature

1980 • 128 citations

Expression of HLA‐DR and common acute lymphoblastic leukemia antigens on glioma cells

1982 • 127 citations

Hydroxyl radical scavengers inhibit human natural killer cell activity

1984 • 126 citations

Nerve growth factor: stimulation of polymorphonuclear leukocyte chemotaxis in vitro.

1983 • 123 citations

Lymphoid cells produce an immunoregulatory glucocorticoid increasing factor (GIF) acting through the pituitary gland.

1985 • 107 citations

In vitro stimulation of glia cells by a lymphocyteproduced factor

1980 • 79 citations

Thymic reticulum in mice III. Phagocytic cells of the thymic reticulum in culture secrete both prostaglandin E₂ and interleukin 1 which regulate thymocyte proliferation

1983 • 77 citations

Biological and biochemical characterization of an interleukin 1‐like factor from rat C₆ glioma cells

1983 • 75 citations

Glia cell stimulating factor (GSF): A new lymphokine

1982 • 63 citations

Generation of cytotoxic lymphocytes to syngeneic tumors by using co-stimulator (Interleukin 2): in vivo activity.

1980 • 51 citations

Lymphoid Cell-Glioma Cell Interaction Enhances Cell Coat Production by Human Gliomas: Novel Suppressor Mechanism

1983 • 46 citations

Glia cell stimulating factor (GSF): A new lymphokine

1982 • 41 citations

In Vitro Studies on the Cell-Mediated Immune Response to Human Brain Tumors. I. Requirement for Third-Party Stimulator Lymphocytes in the Induction of Cell-Mediated Cytotoxic Responses to Allogeneic Cultured Gliomas<xref ref-type="fn" rid="FN2">2</xref>

1982 • 35 citations

Conditioned media from activated lymphocytes maintain sympathetic neurons in culture

1982 • 27 citations

Bayliss‐Starling Memorial Lecture (1982). Induction of sleep by muramyl peptides.

1983 • 24 citations

CBA/N X BALB/cJ F1 male and female mice can be primed to express quantitatively equivalent secondary anti-phosphocholine responses.

1981 • 22 citations

Glia cell response to bacterial lipopolysaccharide

1981 • 13 citations

Glial cell growth-promoting factor in astrocytoma (C6) cell extracts

1981 • 11 citations