Interleukin 2: the molecule and its function

Epidermal Growth Factor

1979 • 2,964 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

Interleukin-2 augments natural killer cell activity

1981 • 921 citations

T‐Cell Growth Factor

1980 • 917 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

The Biochemistry, Biology, and Role of Interleukin 2 in the Induction of Cytotoxic T Cell and Antibody-Forming B Cell Responses

1982 • 524 citations

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor

1983 • 352 citations

Molecular cloning of human interleukin 2 cDNA and its expression inE. coli

1983 • 307 citations

Interleukin 1 is more than an interleukin

1982 • 257 citations

Clones of Killer and Helper T Cells: Growth Requirements, Specificity and Retention of Function in Long‐Term Culture

1980 • 206 citations

Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen.

1983 • 202 citations

Heterogeneity of human T-cell growth factor(s) due to variable glycosylation

1981 • 193 citations

What do the immune system and the brain know about each other?

1983 • 191 citations

Purification of human interleukin 2 to apparent homogeneity and its molecular heterogeneity.

1982 • 155 citations

Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I.

1983 • 136 citations

Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism.

1983 • 118 citations

Gene for T-Cell Growth Factor: Location on Human Chromosome 4q and Feline Chromosome B1

1984 • 97 citations

A rapid, large scale purification procedure for gibbon interleukin 2.

1983 • 94 citations

Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor

1983 • 90 citations

Quantitative representation of all T cells committed to develop into cytotoxic effector cells and/or interleukin 2 activity‐producing helper cells within murine T lymphocyte subsets

1984 • 69 citations

Cell-cycle control in lymphocyte stimulation

1984 • 65 citations

Posttranslational modification of human T-cell growth factor

1983 • 42 citations

Regulation of interleukin 2 receptor expression on murine cytotoxic T lymphocyte clones.

1984 • 38 citations

Purification of mouse interleukin 2 to apparent homogeneity.

1983 • 28 citations

Interleukin 2 is not sufficient for the continuous growth of cloned NK-like cytotoxic cell lines.

1983 • 26 citations

Biochemical characterization of regulatory factors derived from T cell hybridomas and spleen cells. II. Evidence for glycosylation of T cell growth factor, T cell replacing factor, and granulocyte-macrophage colony-stimulating factor.

1982 • 21 citations

Simple Construction of Human c‐myc Gene Implicated in B‐Cell Neoplasmas and Its Relationship with Avian v‐myc and Human Lymphokines

1983 • 12 citations

Studies on T lymphocyte activation. II. Monoclonal antibody inhibiting the capacity of rat T lymphoblasts to absorb and to respond to IL-2: an anti-IL-2 receptor antibody?

1983 • 9 citations