The enigma of oligoclonal immunoglobulin G in cerebrospinal fluid from multiple sclerosis patients

Unconventional Viruses and the Origin and Disappearance of Kuru

1977 • 897 citations

AN ELECTROPHORETIC STUDY OF THE PROTEIN COMPONENTS IN CEREBROSPINAL FLUID AND THEIR RELATIONSHIP TO THE SERUM PROTEINS 1

1942 • 457 citations

Immunoglobulins in Multiple Sclerosis and Infections of the Nervous System

1971 • 296 citations

Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymus-independent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency.

1980 • 258 citations

On cerebrospinal fluid immunoglobulin-G (IgG) quotients in multiple sclerosis and other diseases

1970 • 246 citations

Oligoclonal Measles Virus‐Specific IgG Antibodies Isolated from Cerebrospinal Fluids, Brain Extracts, and Sera from Patients with Subacute Sclerosing Panencephalitis and Multiple Sclerosis

1976 • 195 citations

FUSION OF CULTURED MULTIPLE-SCLEROSIS BRAIN CELLS WITH INDICATOR CELLS: PRESENCE OF NUCLEOCAPSIDS AND VIRIONS AND ISOLATION OF PARAINFLUENZA-TYPE VIRUS

1972 • 195 citations

A STUDY OF THE CRYSTALLINE ALBUMIN, GAMMA GLOBULIN AND TOTAL PROTEIN IN THE CEREBROSPINAL FLUID OF ONE HUNDRED CASES OF MULTIPLE SCLEROSIS AND IN OTHER DISEASES

1950 • 184 citations

IMMUNOGLOBULIN-CONTAINING CELLS IN MULTIPLE-SCLEROSIS PLAQUES

1977 • 176 citations

Immunological Diseases.

1979 • 168 citations

Untersuchungen mit J131-markiertem ?-Globulin zur Frage der Abstammung der Liquoreiweissk�rper

1958 • 154 citations

Isoelectric focusing of IgG eluted from multiple sclerosis and subacute sclerosing panencephalitis brains

1980 • 145 citations

Multiple Sclerosis Research

2013 • 144 citations

Immunoglobulin Abnormalities in Multiple Sclerosis

1973 • 144 citations

CIRCULATING IMMUNE COMPLEXES IN MULTIPLE SCLEROSIS AND OTHER NEUROLOGICAL DISEASES

1976 • 141 citations

Multiple sclerosis in twins

1980 • 114 citations

Multiple sclerosis: Diagnostic usefulness of cerebrospinal fluid

1977 • 114 citations

Binding of normal human IgG to myelin sheaths, glia and neurons.

1975 • 107 citations

Immunoglobulin abnormalities in multiple sclerosis

1976 • 107 citations

Agarose electrophoresis of cerebrospinal fluid in multiple sclerosis

1977 • 103 citations

Brain fibroblast growth factor: nonidentity with myelin basic protein fragments.

1980 • 102 citations

Clinical Neuroimmunology

1980 • 98 citations

IMMUNOGLOBULIN SYNTHESIS WITHIN THE CENTRAL NERVOUS SYSTEM IN DISSEMINATED SCLEROSIS

1967 • 97 citations

Oligoclonal IgG and free light chains in multiple sclerosis demonstrated by thin‐layer polyacrylamide gel isoelectric focusing and immunofixation

1980 • 95 citations

Immunoglobulin class and light chain type of oligoclonal bands in CSF in multiple sclerosis determined by agarose gel electrophoresis and immunofixation

1979 • 92 citations

Comparison between agarose gel electrophoresis and isoelectric focusing of CSF for demonstration of oligoclonal immunoglobulin bands in neurological disorders

2009 • 92 citations

IgG1 Subclass Restriction of Oligoclonal IgG from Cerebrospinal Fluids and Brain Extracts in Patients with Multiple Sclerosis and Subacute Encephalitides

1976 • 91 citations

A COMPARISON BETWEEN AGAR GEL ELECTROPHORESIS and CSF SERUM QUOTIENTS of IgG and ALBUMIN IN NEUROLOGICAL DISEASES

1976 • 82 citations

Multiple Sclerosis: Brain Immunoglobulin-G and Albumin

1967 • 76 citations

Demonstration of Electrophoretically Restricted Virus‐Specific Antibodies in Serum and Cerebrospinal Fluid by Imprint Electroimmunofixation

1978 • 70 citations

Immunoglobulins in the cerebrospinal fluid: changes during acute viral encephalitis in mice.

1981 • 70 citations

LABORATORY DIAGNOSIS OF MULTIPLE SCLEROSIS: IMMUNOLOGICAL AND BIOCHEMICAL ASPECTS

1977 • 70 citations

The specificity of T-cell helper factor in man

1977 • 67 citations

Lymphocyte Subpopulations in the Cerebrospinal Fluid and Peripheral Blood in Patients with Multiple Sclerosis

1975 • 64 citations

Spinal Fluid Differences in Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1978 • 63 citations

MICRO‐ELECTROPHORESIS IN AGAR GEL OF PROTEINS OF THE CEREBROSPINAL FLUID AND CENTRAL NERVOUS SYSTEM

1959 • 55 citations

Fluorescent Protein Tracing in Multiple Sclerosis Brain Tissue

1969 • 48 citations

STUDIES ON ACUTE DISSEMINATED ENCEPHALOMYELITIS PRODUCED EXPERIMENTALLY IN RHESUS MONKEYS

1951 • 47 citations

Disproportionate elevation of the immunoglobulin G1 concentration in cerebrospinal fluids of patients with multiple sclerosis

1979 • 40 citations

IgG1 Subclass Restriction of Oligoclonal Measles Virus‐Specific IgG Antibodies in Patients with Subacute Sclerosing Panencephalitis and in a Patient with Multiple Sclerosis

1977 • 39 citations

Relationship between measles virus-specific antibody activities and oligoclonal IgG in the central nervous system of patients with subacute sclerosing panencephalitis and multiple sclerosis

1975 • 34 citations

Clinical Aspects of Neuroimmunology

1980 • 31 citations

Antigen-Binding Lymphocytes in Normal Man and Guinea Pig to Human Encephalitogenic Protein

1973 • 31 citations

Clinical Aspects of Neuroimmunology

1979 • 29 citations

Cerebrospinal fluid and serum oligoclonal IgG bands in rabbits with experimental allergic encephalomyelitis

1981 • 24 citations

Cerebrospinal fluid immune complexes in multiple sclerosis

1979 • 22 citations

Endogenous myelin basic protein-serum factors (MBP-SFs) in Lewis rats

1981 • 21 citations

The fourth international congress of immunology

1979 • 21 citations

Acute experimental allergic encephalomyelitis

1979 • 20 citations

ISOLATION AND CHARACTERIZATION OF THE INFLAMMATORY INFILTRATE IN THE CENTRAL NERVOUS SYSTEM OF THE GUINEA‐PIG WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1980 • 17 citations

An assay for human lymphocyte mitogenic factor: B-lymphocyte stimulation by a T-lymphocyte product

1978 • 14 citations

The elution of IgG from subacute sclerosing panencephalitis and multiple sclerosis brains.

1980 • 12 citations

QUANTITATION AND IN VITRO ANALYSIS OF THE INFLAMMATORY CELLS IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN THE GUINEA‐PIG

1981 • 9 citations