AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics

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AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

2007 • 4,123 citations

The CCPN data model for NMR spectroscopy: Development of a software pipeline

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TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

2009 • 2,447 citations

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

2002 • 2,371 citations

Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation

1994 • 2,051 citations

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

1999 • 1,683 citations

Parts per Million Mass Accuracy on an Orbitrap Mass Spectrometer via Lock Mass Injection into a C-trap

2005 • 1,508 citations

Positional cloning of the APECED gene

1997 • 1,385 citations

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1997 • 1,155 citations

Searching protein structure databases with DaliLite v.3

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Using NMRView to Visualize and Analyze the NMR Spectra of Macromolecules

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The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

2006 • 561 citations

Aire

2009 • 533 citations

ARIA2: Automated NOE assignment and data integration in NMR structure calculation

2006 • 519 citations

The PHD finger: a versatile epigenome reader

2011 • 433 citations

PHD Domain-Mediated E3 Ligase Activity Directs Intramolecular Sumoylation of an Adjacent Bromodomain Required for Gene Silencing

2007 • 390 citations

Aire's Partners in the Molecular Control of Immunological Tolerance

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Tautomeric states of the active‐site histidines of phosphorylated and unphosphorylated III^Glc, a signal‐transducing protein from escherichia coli, using two‐dimensional heteronuclear NMR techniques

1993 • 294 citations

The Autoimmune Regulator Protein Has Transcriptional Transactivating Properties and Interacts with the Common Coactivator CREB-binding Protein

2000 • 239 citations

The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression

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Autoimmune Polyendocrine Syndrome Type 1 in Norway: Phenotypic Variation, Autoantibodies, and Novel Mutations in the Autoimmune Regulator Gene

2006 • 212 citations

Handpicking epigenetic marks with PHD fingers

2011 • 208 citations

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

2010 • 201 citations

Identifying Dynamic Interactors of Protein Complexes by Quantitative Mass Spectrometry

2007 • 191 citations

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex

2008 • 170 citations

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity

2008 • 167 citations

APECED-causing mutations in AIRE reveal the functional domains of the protein

2004 • 109 citations

A Novel Proteomics Approach for the Discovery of Chromatin-associated Protein Networks

2008 • 108 citations

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

2008 • 96 citations

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: known and novel aspects of the syndrome

2011 • 95 citations

NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1)

2005 • 89 citations

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

2009 • 86 citations

Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator

2009 • 78 citations

DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity

2007 • 71 citations

Subcellular Expression of Autoimmune Regulator Is Organized in a Spatiotemporal Manner

2004 • 71 citations

Quantitative Proteomics Reveals Regulation of Dynamic Components within TATA-binding Protein (TBP) Transcription Complexes

2007 • 69 citations

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3

2010 • 60 citations

Evolutionarily conserved and divergent regions of the Autoimmune Regulator (Aire) gene: a comparative analysis

2008 • 58 citations

Autoantibodies against Aromatic l-Amino Acid Decarboxylase Identifies a Subgroup of Patients with Addison’s Disease1

2000 • 57 citations

Unmodified Histone H3K4 and DNA-Dependent Protein Kinase Recruit Autoimmune Regulator to Target Genes

2012 • 38 citations

Role of PHD fingers and COOH-terminal 30 amino acids in AIRE transactivation activity

2007 • 36 citations

Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription

2011 • 32 citations

Autoantibodies against Aromatic L-Amino Acid Decarboxylase Identifies a Subgroup of Patients with Addison's Disease

2000 • 29 citations

PHD finger of autoimmune regulator: An epigenetic link between the histone modifications and tissue-specific antigen expression in thymus

2008 • 18 citations