NMR Structure of the First PHD Finger of Autoimmune Regulator Protein (AIRE1)

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1998 • 15,791 citations

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

MOLMOL: A program for display and analysis of macromolecular structures

1996 • 7,169 citations

AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

2002 • 4,069 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

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1999 • 2,966 citations

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

2002 • 2,371 citations

Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation

1994 • 2,051 citations

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

1999 • 1,683 citations

Modeller: Generation and Refinement of Homology-Based Protein Structure Models

2003 • 1,660 citations

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

1995 • 1,618 citations

Positional cloning of the APECED gene

1997 • 1,385 citations

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1997 • 1,155 citations

Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53

2000 • 1,026 citations

Using NMRView to Visualize and Analyze the NMR Spectra of Macromolecules

2004 • 1,010 citations

The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

Structural classification of zinc fingers: SURVEY AND SUMMARY

2003 • 852 citations

Structure of a c-Cbl–UbcH7 Complex

2000 • 824 citations

The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation

2001 • 623 citations

The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

2003 • 467 citations

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

2002 • 463 citations

Three-dimensional structure of ectatomin from Ectatomma tuberculatum ant venom

1995 • 363 citations

Mutations in the AIRE Gene: Effects on Subcellular Location and Transactivation Function of the Autoimmune Polyendocrinopathy-Candidiasis–Ectodermal Dystrophy Protein

2000 • 358 citations

Automated Assignment of Ambiguous Nuclear Overhauser Effects with ARIA

2001 • 346 citations

The PHD Domain of MEKK1 Acts as an E3 Ubiquitin Ligase and Mediates Ubiquitination and Degradation of ERK1/2

2002 • 314 citations

Tautomeric states of the active‐site histidines of phosphorylated and unphosphorylated III^Glc, a signal‐transducing protein from escherichia coli, using two‐dimensional heteronuclear NMR techniques

1993 • 294 citations

A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition

2001 • 281 citations

R-factor, FreeR, and Complete Cross-Validation for Dipolar Coupling Refinement of NMR Structures

1999 • 239 citations

The Autoimmune Regulator Protein Has Transcriptional Transactivating Properties and Interacts with the Common Coactivator CREB-binding Protein

2000 • 239 citations

The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.

2001 • 222 citations

Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains

2001 • 197 citations

Structure of the PHD Zinc Finger from Human Williams-Beuren Syndrome Transcription Factor

2000 • 155 citations

AIRE Functions As an E3 Ubiquitin Ligase

2004 • 145 citations

PHD domains and E3 ubiquitin ligases: viruses make the connection

2002 • 145 citations

Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

2002 • 141 citations

APECED mutations in the autoimmune regulator (AIRE) gene

2001 • 140 citations

Autoimmune regulator: from loss of function to autoimmunity

2003 • 137 citations

Subcellular Localization of the Autoimmune Regulator Protein

2001 • 127 citations

Nucleosome Binding by the Bromodomain and PHD Finger of the Transcriptional Cofactor p300

2004 • 125 citations

Structural Model of the UbcH5B/CNOT4 Complex Revealed by Combining NMR, Mutagenesis, and Docking Approaches

2004 • 121 citations

AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers

1999 • 113 citations

ACF1 improves the effectiveness of nucleosome mobilization by ISWI through PHD–histone contacts

2004 • 111 citations

APECED-causing mutations in AIRE reveal the functional domains of the protein

2004 • 109 citations

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunity

2004 • 103 citations

Solution Structure of the Kaposi's Sarcoma-associated Herpesvirus K3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain

2004 • 96 citations

Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting

2002 • 94 citations

Scores of RINGS but No PHDs in Ubiquitin Signaling

2003 • 87 citations

Subcellular Expression of Autoimmune Regulator Is Organized in a Spatiotemporal Manner

2004 • 71 citations

Engineering a Protein Scaffold from a PHD Finger

2003 • 66 citations

Crystal Structure and Nuclear Magnetic Resonance Analyses of the SAND Domain from Glucocorticoid Modulatory Element Binding Protein-1 Reveals Deoxyribonucleic Acid and Zinc Binding Regions

2003 • 44 citations

In vitro assays to study protein ubiquitination in transcription

2002 • 16 citations