Antithrombin III Prevents and Rapidly Reverses Leukocyte Recruitment in Ischemia/Reperfusion

Adhesion receptors of the immune system

1990 • 6,585 citations

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Superoxide radicals in feline intestinal ischemia

1981 • 1,213 citations

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

1983 • 1,168 citations

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

1990 • 997 citations

Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis

1990 • 989 citations

Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo.

1991 • 977 citations

Selectins.

1993 • 869 citations

Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury

1988 • 794 citations

Endothelial cell interactions with granulocytes: tethering and signaling molecules

1992 • 773 citations

Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo

1990 • 739 citations

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

1987 • 704 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils.

1991 • 605 citations

Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.

1991 • 600 citations

GMP-140 mediates adhesion of stimulated platelets to neutrophils

1990 • 515 citations

C5a-induced expression of P-selectin in endothelial cells.

1994 • 470 citations

In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

1993 • 452 citations

Leukocyte adherence to venular endothelium during ischemia-reperfusion

1989 • 381 citations

Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro.

1985 • 380 citations

Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons.

1992 • 368 citations

Leukocyte-endothelium adhesion: Microhemodynamics in mesentery of the cat

1987 • 347 citations

Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion.

1992 • 296 citations

Antibody to CD-18 exerts endothelial and cardiac protective effects in myocardial ischemia and reperfusion.

1991 • 296 citations

Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells.

1987 • 281 citations

Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion.

1995 • 256 citations

Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin

1987 • 254 citations

Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium.

1993 • 238 citations

Role of platelet-activating factor in ischemia/reperfusion-induced leukocyte adherence

1990 • 226 citations

Leukocyte depletion attenuates vascular injury in postischemic skeletal muscle

1988 • 221 citations

Superoxide mediates reperfusion-induced leukocyte-endothelial cell interactions

1989 • 215 citations

Leukotrienes as mediators in ischemia-reperfusion injury in a microcirculation model in the hamster.

1991 • 212 citations

Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling

1993 • 205 citations

NO donors prevent integrin-induced leukocyte adhesion but not P-selectin-dependent rolling in postischemic venules

1994 • 171 citations

Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells.

1990 • 163 citations

Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear.

1993 • 149 citations

The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes

1994 • 145 citations

Chemoattractant‐induced firm adhesion of leukocytes to vascular endothelium in vivo is critically dependent on initial leukocyte rolling

1992 • 130 citations

Thrombin receptor-activating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells.

1994 • 106 citations

Role of leukotriene B4 in granulocyte infiltration into the postischemic feline intestine

1990 • 106 citations

Adenosine inhibits ischemia-reperfusion-induced leukocyte adherence and extravasation

1989 • 99 citations

The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation.

1993 • 95 citations

Modified platelet responses to thrombin. Evidence for two types of receptors or coupling mechanisms.

1986 • 94 citations

Low-dose chymotrypsin treatment inhibits neutrophil migration into sites of inflammation in vivo: Effects on Mac-1 and MEL-14 adhesion protein expression and function

1991 • 93 citations

Inhibition of tyrosine phosphorylation prevents thrombin-induced mitogenesis, but not intracellular free calcium release, in vascular smooth muscle cells.

1992 • 89 citations

Desmopressin induces endothelial P-selectin expression and leukocyte rolling in postcapillary venules

1995 • 87 citations

Leukocyte-Endothelial Cell Adhesive Interactions: Role of Xanthine Oxidase-Derived Oxidants

1991 • 85 citations

Neutrophil elastase and oxygen radicals: synergism in lung injury after hindlimb ischemia

1991 • 76 citations

Thrombin Receptor Structure and Function

1993 • 73 citations

Thrombin Stimulates Neutrophil Adherence by an Endothelial Cell‐Dependent Mechanism: Characterization of the Response and Relationship to Platelet‐Activating Factor Synthesis^a

1986 • 70 citations

Response of blood leukocytes to thrombin receptor peptides

1993 • 47 citations

Effects of Leukotriene A₄ on Neutrophil Activation^a

1994 • 6 citations