Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear.

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo.

1991 • 977 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 962 citations

Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury

1988 • 794 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 785 citations

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

1987 • 704 citations

Ischemia-reperfusion injury: role of oxygen-derived free radicals.

1986 • 680 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion.

1988 • 650 citations

Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils.

1991 • 605 citations

Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.

1981 • 587 citations

Recurrent Severe Infections Caused by a Novel Leukocyte Adhesion Deficiency

1992 • 555 citations

A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo

1987 • 525 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1991 • 505 citations

Contributions of ischemia and reperfusion to mucosal lesion formation

1986 • 477 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 473 citations

In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

1993 • 452 citations

Complement Proteins C5b-9 Induce Secretion of High Molecular Weight Multimers of Endothelial von Willebrand Factor and Translocation of Granule Membrane Protein GMP-140 to the Cell Surface

1989 • 442 citations

A monoclonal antibody to the adherence-promoting leukocyte glycoprotein, CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits.

1988 • 434 citations

Membrane Proteins Involved in Phagocyte Adherence to Endothelium

1990 • 407 citations

Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.

1991 • 398 citations

Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140).

1992 • 385 citations

Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.

1992 • 383 citations

Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits

1985 • 369 citations

Improved method for quantification of tissue PMN accumulation measured by myeloperoxidase activity

1990 • 356 citations

Intracellular control of human neutrophil secretion. I. C5a-induced stimulus-specific desensitization and the effects of cytochalasin B.

1978 • 283 citations

GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interaction.

1991 • 247 citations

Endothelial leukocyte adhesion molecule-1 mediates antigen-induced acute airway inflammation and late-phase airway obstruction in monkeys.

1991 • 233 citations

GMP‐140: A receptor for neutrophils and monocytes on activated platelets and endothelium

1991 • 212 citations

Inhibition of leukocyte adherence by anti-CD18 monoclonal antibody attenuates reperfusion injury in the rabbit ear.

1990 • 205 citations

Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock.

1989 • 192 citations

The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.

1991 • 175 citations

STUDIES ON THE PATHOGENESIS OF ACUTE INFLAMMATION

1955 • 165 citations

Role of neutrophils in hemorrhagic shock-induced gastric mucosal injury in the rat

1987 • 161 citations

Inhibition of CD18-dependent neutrophil adherence reduces organ injury after hemorrhagic shock in primates.

1990 • 158 citations

An evaluation of the neutrophil as a mediator of in vivo renal ischemic-reperfusion injury.

1989 • 145 citations

Antibody against leukocyte integrin (CD18) prevents reperfusion-induced lung vascular injury

1990 • 104 citations

Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated platelets

1990 • 102 citations

Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock

1990 • 76 citations

A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo

1987 • 60 citations

Pulmonary edema induced by phagocytosing neutrophils. Protective effect of monoclonal antibody against phagocyte CD18 integrin.

1990 • 53 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 43 citations

Leukocyte-Mediated Endothelial Injury

1992 • 1 citations