The 1.6-Å crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

1997 • 14,729 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Solvent content of protein crystals

1968 • 7,954 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein

2002 • 3,280 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

ESPript: analysis of multiple sequence alignments in PostScript.

1999 • 2,820 citations

XtalView/Xfit—A Versatile Program for Manipulating Atomic Coordinates and Electron Density

1999 • 2,108 citations

The α/β hydrolase fold

1992 • 2,024 citations

Serine Proteases: Structure and Mechanism of Catalysis

1977 • 1,238 citations

Posttranslational Quality Control: Folding, Refolding, and Degrading Proteins

1999 • 1,064 citations

A Temperature-Dependent Switch from Chaperone to Protease in a Widely Conserved Heat Shock Protein

1999 • 747 citations

Genome-wide expression profiling in Escherichia coli K-12

1999 • 584 citations

Protein quality control: triage by chaperones and proteases.

1997 • 543 citations

Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine

2002 • 403 citations

Three-dimensional structure of a transglutaminase: human blood coagulation factor XIII.

1994 • 343 citations

Review: Mechanisms of Disaggregation and Refolding of Stable Protein Aggregates by Molecular Chaperones

2001 • 237 citations

The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families

1996 • 228 citations

Maximum-likelihood density modification using pattern recognition of structural motifs

2001 • 135 citations

Structure of carboxypeptidase B at 2.8 Å resolution

1976 • 121 citations

Crystal structure of an intracellular protease fromPyrococcus horikoshiiat 2-Å resolution

2000 • 106 citations

Hsp31, the Escherichia coli yedU Gene Product, Is a Molecular Chaperone Whose Activity Is Inhibited by ATP at High Temperatures

2002 • 77 citations

Function of the Escherichia coli nucleoid protein, H-NS molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant

1993 • 70 citations

Purification and Characterization of Two Functional Forms of Intracellular Protease PfpI from the Hyperthermophilic Archaeon Pyrococcus furiosus

1997 • 44 citations

A computer system to perform structure comparison using TOPS representations of protein structure

2001 • 40 citations

Crystallization and preliminary X-ray crystallographic analysis of ayedUgene product fromEscherichia coli

2002 • 2 citations