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Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

Data up to Jan 2025

Published1990
Citations541
References27

Total Citations Per Year

Abstract

References (27)

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1986 • 1,058 citations

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1987 • 719 citations

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1988 • 634 citations

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

1989 • 570 citations

Reversal of Chloroquine Resistance in Plasmodium falciparum by Verapamil

1987 • 558 citations

Efflux of Chloroquine from Plasmodium falciparum : Mechanism of Chloroquine Resistance

1987 • 523 citations

Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.

1988 • 507 citations

Amplification of a Gene Related to Mammalian mdr Genes in Drug-Resistant Plasmodium falciparum

1989 • 439 citations

Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria.

1990 • 417 citations

Complete in vitro maturation of Plasmodium falciparum gametocytes

1981 • 311 citations

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance.

1990 • 304 citations

Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine.

1984 • 301 citations

Antimalarials increase vesicle pH in Plasmodium falciparum.

1985 • 252 citations

Cloning of Naturally Occurring Mixed Infections of Malaria Parasites

1981 • 221 citations

A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum

1987 • 211 citations

Susceptibility of human malaria parasites to chloroquine is pH dependent.

1985 • 181 citations

A chromosomal rearrangement in a P. falciparum histidine-rich protein gene is associated with the knobless phenotype

1986 • 175 citations

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1982 • 163 citations

Plasmodium falciparum: Induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro

1988 • 140 citations

Analysis of sequences from the extremely A + T-rich genome of Plasmodium falciparum

1987 • 136 citations

Gametocyte-Forming and Non-Gametocyte-Forming Clones of Plasmodium Falciparum

1984 • 132 citations

Acid-Vesicle Function, Intracellular Pathogens, and the Action of Chloroquine againstPlasmodium falciparum

1987 • 103 citations

Isolation of the Gene for a Glycophorin-Binding Protein Implicated in Erythrocyte Invasion by a Malaria Parasite

1985 • 89 citations

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1979 • 68 citations

Histidine-rich domain of the knob protein of the human malaria parasite Plasmodium falciparum.

1986 • 40 citations

Export-import family expands

1989 • 29 citations

Protein joins transport family

1989 • 28 citations

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Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross (1990) – Nature | Metascience Observatory Explorer