Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine.

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Lysosomotropic agents

1974 • 1,887 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Determination of DeltapH in Chloroplasts. 2. Fluorescent Amines as a Probe for the Determination of DeltapH in Chloroplasts

1972 • 649 citations

Binding of Diffusible Molecules by Macromolecules: Rapid Measurement by Rate of Dialysis

1969 • 517 citations

Lysosomes, pH and the Anti-malarial Action of Chloroquine

1972 • 501 citations

Lysosomes revisited

1983 • 427 citations

Concentration from Continuous Culture of Erythrocytes Infected with Trophozoites and Schizonts of Plasmodium Falciparum *

1978 • 288 citations

The permeability properties of the lysosomal membrane

1977 • 198 citations

Effects of Chloroquine on the Feeding Mechanism of the Intraerythrocytic Human Malarial ParasitePlasmodium falciparum1

1984 • 126 citations

Chloroquine: Physiological Basis of Drug Resistance in Plasmodium berghei

1966 • 116 citations

Plasmodium falciparum: Physiological interactions with the human sickle cell

1979 • 109 citations

ANTIMALARIAL DRUG RESISTANCE: AN INCREASING PROBLEM

1982 • 98 citations

High-resolution autoradiography of malarial parasites treated with 3 H-chloroquine.

1972 • 93 citations

Alterations in membrane permeability of malaria-infected human erythrocytes are related to the growth stage of the parasite

1982 • 84 citations

Peptidases from Plasmodium falciparum cultured in vitro

1982 • 78 citations

High-Affinity Accumulation of Chloroquine by Mouse Erythrocytes Infected with Plasmodium berghei

1974 • 69 citations

Membrane potential of Plasmodium-infected erythrocytes.

1982 • 64 citations

Involvement of spectrin and ATP in infection of resealed erythrocyte ghosts by the human malarial parasite, Plasmodium falciparum.

1982 • 52 citations

Mode of Action of Antimalarial Drugs

1983 • 43 citations

Localization of Acid Phosphatase Activity in Plasmodium berghei and P. gallinaceum: An Electron Microscopic Observation

1971 • 30 citations

Chloroquine inhibits the degradation of endocytic vesicles in human malaria parasites

1983 • 26 citations

Properties of a synthetic plasma membrane marker: Fluorescent-Mercury-Dextran

1973 • 15 citations

Isolation of chloroquine-resistant Chinese hamster V79 cell variants that are also resistant to ammonium chloride.

1983 • 6 citations

Malaria studiesin vitro

1975 • 3 citations