Back to search

Protein binding versus protein folding: the role of hydrophilic bridges in protein associations 1 1Edited by B. Honig

Data up to Jan 2025

Published1997
Citations228
References92

Total Citations Per Year

Abstract

References (92)

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Regression Diagnostics -- Identifying Influential Data and Sources of Collinearity

1981 • 6,625 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

Dominant forces in protein folding

1990 • 3,682 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Classical Electrostatics in Biology and Chemistry

1995 • 2,801 citations

AREAS, VOLUMES, PACKING, AND PROTEIN STRUCTURE

1977 • 2,631 citations

Analytical molecular surface calculation

1983 • 2,454 citations

Applied Linear Statistical Models.

1975 • 2,369 citations

Solvation energy in protein folding and binding

1986 • 1,853 citations

A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants

1993 • 1,456 citations

Electrostatic Interactions in Macromolecules: Theory and Applications

1990 • 1,324 citations

Shape complementarity at protein–protein interfaces

1994 • 1,217 citations

Calculating the electrostatic potential of molecules in solution: Method and error assessment

1988 • 1,096 citations

Calculations of electrostatic interactions in biological systems and in solutions

1984 • 992 citations

Calculation of the electric potential in the active site cleft due to α-helix dipoles

1982 • 931 citations

Energy of an Ion crossing a Low Dielectric Membrane: Solutions to Four Relevant Electrostatic Problems

1969 • 832 citations

Calculation of the total electrostatic energy of a macromolecular system: Solvation energies, binding energies, and conformational analysis

1988 • 829 citations

The structure of protein-protein recognition sites.

1990 • 825 citations

Focusing of electric fields in the active site of Cu‐Zn superoxide dismutase: Effects of ionic strength and amino‐acid modification

1986 • 759 citations

Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids

1993 • 737 citations

Do salt bridges stabilize proteins? A continuum electrostatic analysis

1994 • 629 citations

The molecular surface package

1993 • 590 citations

Electrostatic recognition between superoxide and copper, zinc superoxide dismutase

1983 • 540 citations

Macroscopic models of aqueous solutions: biological and chemical applications

1993 • 520 citations

Electrostatic Energy and Macromolecular Function

1991 • 463 citations

The dielectric constant of a folded protein

1986 • 452 citations

Calculation of electrostatic potentials in an enzyme active site

1987 • 449 citations

Studies of protein‐protein interfaces: A statistical analysis of the hydrophobic effect

1997 • 422 citations

Faster superoxide dismutase mutants designed by enhancing electrostatic guidance

1992 • 387 citations

A role for surface hydrophobicity in protein‐protein recognition

1994 • 377 citations

Reshaping Human Antibodies: Grafting an Antilysozyme Activity

1988 • 348 citations

On the calculation of electrostatic interactions in proteins

1985 • 331 citations

Calculation of the free energy of association for protein complexes

1992 • 326 citations

Are buried salt bridges important for protein stability and conformational specificity?

1995 • 323 citations

Electrostatic Effects in Proteins

1985 • 310 citations

Free Energy Balance in Protein Folding

1995 • 274 citations

Binding of small basic peptides to membranes containing acidic lipids: theoretical models and experimental results

1996 • 273 citations

Calculations of electrostatic energies in proteins

1985 • 270 citations

Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme

1991 • 265 citations

Metal Ion-Dependent Modulation of the Dynamics of a Designed Protein

1993 • 252 citations

Conformational stability of dimeric proteins: Quantitative studies by equilibrium denaturation

1994 • 248 citations

Dielectric relaxation spectra of water adsorbed on lysozyme

1972 • 221 citations

Secondary structure of the α-amylase polypeptide inhibitor Tendamistat from Streptomyces tendae determined in solution by 1H nuclear magnetic resonance

1985 • 200 citations

Hydrophobic docking: A proposed enhancement to molecular recognition techniques

1994 • 191 citations

Accelerated molecular dynamics simulation with the parallel fast multipole algorithm

1992 • 189 citations

A geometry-based suite of moleculardocking processes

1995 • 184 citations

Multivariate Analysis

1983 • 180 citations

Entropy in biological binding processes: Estimation of translational entropy loss

1994 • 179 citations

Stability of "salt bridges" in membrane proteins.

1984 • 176 citations

Modern Electrochemistry

1972 • 167 citations

A Continuum Model for Protein–Protein Interactions: Application to the Docking Problem

1995 • 166 citations

Protein‐protein recognition analyzed by docking simulation

1991 • 147 citations

On the environment of ionizable groups in globular proteins

1984 • 145 citations

Role of hydrophobicity in the binding of coenzymes

1978 • 133 citations

CONVERSION OF LIGHT ENERGY TO ELECTROSTATIC ENERGY IN THE PROTON PUMP OF HALOBACTERIUM HALOBIUM

1979 • 126 citations

Molecular Surface Complementarity at Protein-Protein Interfaces: The Critical Role Played by Surface Normals at Well Placed, Sparse, Points in Docking

1995 • 117 citations

A preference-based free-energy parameterization of enzyme-inhibitor binding. Applications to HIV-1-protease inhibitor design

1995 • 117 citations

Dielectric Dispersion of Crystalline Powders of Amino Acids, Peptides, and Proteins1

1965 • 115 citations

Molecular surface representations by sparse critical points

1994 • 110 citations

Directed mutagenesis and barnase-barstar recognition

1993 • 104 citations

Affinity and Specificity of Serine Endopeptidase-Protein Inhibitor Interactions

1993 • 100 citations

Electrostatic fields in antibodies and antibody/antigen complexes

1992 • 99 citations

Why ion pair reversal by protein engineering is unlikely to succeed

1988 • 93 citations

Microscopic theory of the dielectric properties of proteins

1991 • 92 citations

Surface electrostatics, reduction potentials, and the internal dielectric constant of proteins

1991 • 91 citations

What about protein polarity?

1987 • 89 citations

Structure of an Antibody–Lysozyme Complex Unexpected Effect of a Conservative Mutation

1995 • 87 citations

A de novo designed protein shows a thermally induced transition from a native to a molten globule-like state

1992 • 79 citations

[58] Carboxypeptidase inhibitor from potatoes

1981 • 78 citations

Protein Response to External Electric Fields: Relaxation, Hysteresis, and Echo

1996 • 75 citations

Structure of Proteins*

1939 • 75 citations

Interpretation of protein folding and binding with atomic solvation parameters

1989 • 73 citations

Amino acid sequence homology between a serine protease inhibitor from barley and potato inhibitor I

1980 • 59 citations

Basis of biological specificity

1984 • 54 citations

Acetylcholinesterase: Role of the enzyme's charge distribution in steering charged ligands toward the active site

1998 • 51 citations

Parallel Computing in Computational Chemistry

1995 • 46 citations

Molecular dynamics study of the M412 intermediate of bacteriorhodopsin

1995 • 46 citations

SPSS 6.1 base system user's guide

1990 • 36 citations

Protein surface area defined

1993 • 36 citations

Molecular Dynamics Simulation on the Connection Machine

1991 • 36 citations

A study of Four-helix Bundles: Investigating Protein FoldingviaSimilar Architectural Motifs in Protein Cores and in Subunit Interfaces

1995 • 32 citations

[60] Eglin: Elastase—Cathepsin G inhibitor from leeches

1981 • 31 citations

Direct Fluorometric Determination of a Dissociation Constant as Low as 10−10 M for the Subtilisin BPN′-Protein Proteinase Inhibitor (Streptomyces Subtilisin Inhibitor) Complex by a Single Photon Counting Technique1

1978 • 30 citations

[42] Correlation between the structure and efficiency of light-induced proton pumps

1986 • 29 citations

Acetylcholinesterase: Role of the enzyme's charge distribution in steering charged ligands toward the active site

1996 • 28 citations

Role of Electrostatics in Antibody-Antigen Association: Anti-Hen Egg Lysozyme/Lysozyme Complex (HyHEL-5/HEL)

1994 • 25 citations

Advanced Algorithms for Molecular Dynamics Simulation

1995 • 17 citations

Hydrophobic Accessible Surface Areas Are Proportional to Binding Energies of Serine Protease-Protein Inhibitor Complexes

1995 • 12 citations

Cited By (0)

Loading...
Protein binding versus protein folding: the role of hydrophilic bridges in protein… (1997) – Journal of Molecular Biology | Metascience Observatory Explorer