Two-component and phosphorelay signal transduction

PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light

1999 • 1,622 citations

Structure of CheA, a Signal-Transducing Histidine Kinase

1999 • 471 citations

The cytoplasmic helical linker domain of receptor histidine kinase and methyl-accepting proteins is common to many prokaryotic signalling proteins

1999 • 395 citations

The Histidine Protein Kinase Superfamily

1999 • 376 citations

A genetic analysis of the function of LuxO, a two‐component response regulator involved in quorum sensing in Vibrio harveyi

1999 • 362 citations

Two-Component Signal Transduction in Bacillus subtilis : How One Organism Sees Its World

1999 • 358 citations

Structure of a biological oxygen sensor: A new mechanism for heme-driven signal transduction

1998 • 356 citations

Emergence of vancomycin tolerance in Streptococcus pneumoniae

1999 • 351 citations

Three-dimensional structure of CheY, the response regulator of bacterial chemotaxis

1989 • 350 citations

A Response Regulator That Represses Transcription of Several Virulence Operons in the Group A Streptococcus

1999 • 273 citations

Histidine kinases: diversity of domain organization

1999 • 260 citations

Compilation and Characterization of Arabiopsis thaliana Response Regulators Implicated in His-Asp Phosphorelay Signal Transduction

1999 • 257 citations

NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ

1998 • 256 citations

A Two-Component Signal Transduction System Essential for Growth of Bacillus subtilis : Implications for Anti-Infective Therapy

1998 • 250 citations

Role in Cell Permeability of an Essential Two-Component System inStaphylococcus aureus

1999 • 244 citations

Cell Cycle–Dependent Polar Localization of an Essential Bacterial Histidine Kinase that Controls DNA Replication and Cell Division

1999 • 241 citations

Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ.

1999 • 234 citations

The Cpx Envelope Stress Response Is Controlled by Amplification and Feedback Inhibition

1999 • 233 citations

Domain dislocation: a change of core structure in periplasmic binding proteins in their evolutionary history

1999 • 217 citations

Differential Localization of Two Histidine Kinases Controlling Bacterial Cell Differentiation

1999 • 197 citations

Millisecond-timescale motions contribute to the function of the bacterial response regulator protein Spo0F

1999 • 191 citations

Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae

1999 • 191 citations

Involvement of the Cpx signal transduction pathway ofE. coliin biofilm formation

1999 • 188 citations

The ethylene-response pathway: signal perception to gene regulation

1999 • 175 citations

How Intracellular Bacteria Survive: Surface Modifications That Promote Resistance to Host Innate Immune Responses

1999 • 174 citations

Roles of Three Histidine Kinase Genes in Hyphal Development and Virulence of the Pathogenic Fungus Candida albicans

1999 • 164 citations

Identification and Disruption of lisRK , a Genetic Locus Encoding a Two-Component Signal Transduction System Involved in Stress Tolerance and Virulence in Listeria monocytogenes

1999 • 161 citations

Histidine-Containing Phosphotransfer (HPt) Signal Transducers Implicated in His-to-Asp Phosphorelay in Arabidopsis

1998 • 160 citations

Two-Component Transcriptional Regulation of N -Acyl-Homoserine Lactone Production in Pseudomonas aureofaciens

1999 • 158 citations

Phosphorylated aspartate in the structure of a response regulator protein 1 1Edited by A. R. Fersht

1999 • 145 citations

Feedback control of a master bacterial cell-cycle regulator

1999 • 144 citations

MicroReview: Functional similarities among two‐component sensors and methyl‐accepting chemotaxis proteins suggest a role for linker region amphipathic helices in transmembrane signal transduction

1999 • 139 citations

A Novel Campylobacter jejuni Two-Component Regulatory System Important for Temperature-Dependent Growth and Colonization

1999 • 133 citations

A novel bacterial tyrosine kinase essential for cell division and differentiation

1999 • 133 citations

Differential Expression of Genes for Response Regulators in Response to Cytokinins and Nitrate in Arabidopsis thaliana

1999 • 126 citations

The CtrA Response Regulator Mediates Temporal Control of Gene Expression during the Caulobacter Cell Cycle

1999 • 124 citations

Formation of a Novel Four-Helix Bundle and Molecular Recognition Sites by Dimerization of a Response Regulator Phosphotransferase

1998 • 108 citations

Molecular mechanisms of cytokinin action

1999 • 103 citations

Phosphorelay signal transduction: the emerging family of plant response regulators

1999 • 102 citations

Molecular Characterization of the PmrA Regulon

1999 • 100 citations

Structural Analysis of Bacterial Chemotaxis Proteins: Components of a Dynamic Signaling System

1998 • 97 citations

The periplasmic domain of the histidine autokinase CitA functions as a highly specific citrate receptor

1999 • 97 citations

Crystal structure and induction mechanism of AmiC-AmiR: a ligand-regulated transcription antitermination complex

1999 • 91 citations

Conservation of structure and function among histidine-containing phosphotransfer (HPt) domains as revealed by the crystal structure of YPD1 1 1Edited by I. A. Wilson

1999 • 88 citations

The RdeA-RegA System, a Eukaryotic Phospho-relay Controlling cAMP Breakdown

1999 • 82 citations

Flocculation of hyphae is associated with a deletion in the putative CaHK1 two-component histidine kinase gene from Candida albicans

1999 • 79 citations

Modulation of Expression of the ToxR Regulon in Vibrio cholerae by a Member of the Two-Component Family of Response Regulators

1998 • 78 citations

Histidine kinases and two-component signal transduction systems

1999 • 77 citations

Avirulence of Candida albicans CaHK1 Mutants in a Murine Model of Hematogenously Disseminated Candidiasis

1999 • 74 citations

Sporulation timing in Myxococcus xanthus is controlled by the espAB locus

1999 • 63 citations

Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae

1999 • 52 citations

Signal transduction: Gyrating protein kinases

1999 • 35 citations

ARR6, a response regulator from Arabidopsis, is differentially regulated by plant nutritional status

1999 • 22 citations

Biochemical and Genetic Evidence for Participation of DevR in a Phosphorelay Signal Transduction Pathway Essential for Heterocyst Maturation in Nostoc punctiforme ATCC 29133

1999 • 22 citations

High energy exchange: proteins that make or break phosphoramidate bonds

1999 • 17 citations